Spatial navigation deficits in amnestic mild cognitive impairment with neuropsychiatric comorbidity

Aims: To find out whether neuropsychiatric comorbidity (comMCI) influences spatial navigation performance in amnestic mild cognitive impairment (aMCI).

Methods: We recruited aMCI patients with (n = 21) and without (n = 21) neuropsychiatric comorbidity or alcohol abuse, matched for global cognitive impairment and cognitively healthy elderly participants (HE, n = 22). They completed the Mini-Mental State Examination and a virtual Hidden Goal Task in egocentric, allocentric, and delayed recall subtests.

Results: In allocentric navigation, aMCI and comMCI performed significantly worse than HE and similarly to each other. Although aMCI performed significantly worse at egocentric navigation than HE, they performed significantly better than patients with comMCI.

Conclusions: Despite the growing burden of dementia and the prevalence of neuropsychiatric symptoms in the elderly population, comMCI remains under-studied. Since trials often assess “pure” aMCI, we may underestimate patients’ navigation and other deficits. This finding emphasizes the importance of taking account of the cognitive effects of psychiatric disorders in aMCI.     

Factors Influencing the Maternal Life Balance of Flemish Mothers,a Cross-Sectional Study

Applied Research in Quality of Life - This cross-sectional study examined the levels of maternal life balance and its influencing factors. The sample was composed of 731 Flemish mothers who...     

Olfactory stimuli and intermale aggression in androgen-treated castrated sheep

The ability of olfactory stimuli to elicit aggression in male sheep was assessed in testosterone-treated castrates. Ablation of the olfactory bulbs (Exp. 1) did not reduce the capacity of sheep to participate in aggressive behaviour after testosterone treatment. Topical application of urine from castrates treated with propionated testosterone, 5α-dihydrotestosterone, 17β-oestradiol, or an oil vehicle to the fleeces of untreated castrates (Exp. 2) did not result in different levels of aggressive responsiveness in testosterone-treated castrates.     

Remembering computer command names: Effects of subject generation versus experimenter imposition

Two experiments analyzed the effectiveness of goal statements in aiding recall of self-generated as opposed to experimenter-imposed command names. Subjects were presented with a series of before-after pairs representing the computer states before and after a command was executed. In Experiment 1, during study, one group of subjects generated a command name in response to each pair; a second group generated a goal statement describing the goal to be accomplished in addition to generating a command name. During recall, half of each group was required to recall the name, whereas the other half was required to describe the goal before attempting to recall the name. In Experiment 2, during study, command names (and goals for those subjects in the goal condition) were imposed by the experimenter rather than generated by the subject. Subjects who generated goals and names recalled more command names than did those who generated only names or who received imposed goals and/or names. Generation of an appropriate goal at study improved encoding by helping subjects to select more appropriate command names; generation of an appropriate goal at test improved retrieval for appropriate names only, presumably by activating a relevant subset of names. Even in the relatively simple task of naming and remembering command names, having an appropriate model of the domain through the use of specific goal statements substantially improved performance.     

Listening and understanding

The activities involved in mediating reinforcement for a speaker's behavior constitute only one phase of a listener's reaction to verbal stimulation. Other phases include listening and understanding what a speaker has said. It is argued that the relative subtlety of these activities is reason for their careful scrutiny, not their complete neglect. Listening is conceptualized as a functional relation obtaining between the responding of an organism and the stimulating of an object. A current instance of listening is regarded as a point in the evolution of similar instances, whereby one's history of perceptual activity may be regarded as existing in one's current interbehavior. Understanding reactions are similarly analyzed; however, they are considerably more complex than listening reactions due to the preponderance of implicit responding involved in reactions of this type. Implicit responding occurs by way of substitute stimulation, and an analysis of the serviceability of verbal stimuli in this regard is made. Understanding is conceptualized as seeing, hearing, or otherwise reacting to actual things in the presence of their "names" alone. The value of an inferential analysis of listening and understanding is also discussed, with the conclusion that unless some attempt is made to elaborate on the nature and operation of these activities, the more apparent reinforcement mediational activities of a listener are merely asserted without an explanation for their occurrence.     

Aggression Toward Gay Men as Gender Role Enforcement: Effects of Male Role Norms, Sexual Prejudice, and Masculine Gender Role Stress

ABSTRACT This study examined sexual prejudice and masculine gender role stress as mediators of the relations between male gender norms and anger and aggression toward gay men. Participants were 150 self-identified heterosexual men who completed measures of adherence to male gender role norms, sexual prejudice, masculine gender role stress, and state anger. Participants then viewed a video depicting intimate relationship behavior between 2 gay men, reported state anger a second time, and competed in a laboratory aggression task against either a heterosexual or a gay male. Results indicated that adherence to the antifemininity norm exerted an indirect effect, primarily through sexual prejudice, on increases in anger. Adherence to the status and antifemininity norms exerted indirect effects, also through sexual prejudice, on physical aggression toward the gay, but not the heterosexual, male. Findings provide the first multivariate evidence for determinants of aggression toward gay men motivated by gender role enforcement.     

Media Coverage of Direct-to-Consumer Genetic Testing

Media coverage of Direct-to-Consumer (DTC) genetic testing shapes public perception of such testing. The purpose of this study was to determine and assess the themes presented by U.S. news media regarding DTC genetic testing. We performed a Lexis-Nexis search with the keywords “Direct-to-Consumer” and “genetic test” for news stories published from 2006–2009. The sample was coded on themes of genetic determinism, privacy, discrimination, validity, regulation, the Genetic Information Nondiscrimination Act (GINA), utility, and cost. Ninety-two news stories were included. Stories displayed moderate genetic determinism and were neutral about validity and utility. Stories indicated that insurance and employers were the most likely sources of discrimination, yet identified the physicians and DTC companies as groups most likely to violate privacy. Stories claimed lack of regulation would harm consumers, but most post-GINA stories did not discuss the law. The costs of tests were frequently included. The results of this study show a broad range of views toward DTC genetic testing and its potential impacts. The genetics community should be aware that the public has been exposed to multiple views of DTC genetic testing when discussing these tests.