Handwriting process and product characteristics of children diagnosed with developmental coordination disorder

Deficits in handwriting performance limit the school participation of children with developmental coordination disorder (DCD). The aim of this study was to compare the handwriting process and product characteristics of children with DCD to those of typically developing (TD) children in order to determine the best means of differentiation between the groups. Participants were 40 children, from 7 to 10 years old. The experimental group consisted of 20 children who met the criteria of DCD, and the control group consisted of 20 age- and gender-matched controls. The children were asked to perform three graded writing tasks on an electronic tablet, which was part of a computerized handwriting evaluation system (ComPET), in order to obtain measures of their handwriting process. The children's handwriting product was then evaluated by the Hebrew Handwriting Evaluation (HHE). Results showed significant differences between the groups for the handwriting process measures (on-paper and in-air time, mean pressure) and for the handwriting product characteristics (global legibility, number of letters erased or overwritten, spatial arrangement, and number of letters written in the first minute). The discriminant analysis yielded a high significant discrimination (80-90%), with the 'number of letters erased or overwritten' variable as the most differentiating variable (-.67). We concluded that an evaluation of both handwriting process and product characteristics among children with DCD provides a more comprehensive picture of their deficits. Using this method may enable practitioners to focus on children's main deficits and to tailor intervention methods so as to prevent academic underachievement and its consequences on their emotional well-being.     

Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent

Very little is known about the biological and molecular mechanisms that determine the effect of previous experience on implicit learning tasks. In the present study, we first defined weak and strong taste inputs according to measurements in the behavioral paradigm known as latent inhibition of conditioned taste aversion. We then demonstrated that a strong novel taste input facilitated acquisition of the memory of subsequent weak taste input in inverse correlation with the time interval between the inputs. However, not only was a strong taste input unable to rescue an immediately subsequent strong taste input when the gustatory cortex was under the influence of the protein-synthesis inhibitor, anisomycin, but the effect of the interaction was to reduce the variation among individual taste memories. Taken together, these results demonstrate that taste memory facilitation, induced by previously experiencing a different unimodal taste input, depended on time, novelty, and directionality. Moreover, the results imply that learning is enhanced on the level of acquisition but not of molecular consolidation.     

Community-delivered infant–parent psychotherapy improves maternal sensitive caregiving: Evaluation of the Michigan model of infant mental health home visiting

The current study evaluated the effectiveness of a home-based psychotherapeutic Infant Mental Health Home Visiting (IMH-HV) intervention for enhancing parenting sensitivity; a secondary aim was to evaluate whether the use of video feedback was associated with greater treatment response. Participants were N = 78 mothers and their children (age at entry ranged from prebirth to 24-month old (M = 9.8, SD = 8.4), who were initiating IMH-HV services with community mental health-based therapists (N = 51). Dyads were assessed during extended home visits via standardized interviews and observational and questionnaire methods within the first month of treatment (baseline), and again 6 and 12 months thereafter. Following each of these extended home visits, study evaluators completed a standard Q-sort to capture observations of maternal sensitivity during the visit. Therapists completed fidelity checklists used to derive the total number of IMH-HV sessions received (i.e., dosage) and frequency with which therapists provided video feedback. Results indicated a dose–response relationship between number of sessions and maternal sensitivity, and that video review with parents independently contributed to improved maternal sensitivity. Discussion focuses on the effectiveness of this community-based psychotherapeutic home visiting model for enhancing parenting, as well as the value of video feedback as a specific therapeutic strategy.     

Hearing Silent Shapes: Identifying the Shape of a Sound-Obstructing Surface

Two experiments test whether the shape of objects that obstruct sound can be perceived by human listeners. Three foam-core shapes of equal area—disk, square, and triangle—were positioned in front a set of loudspeakers, which emanated broadband noise. On each trial, blindfolded listeners were asked to identify which shape obstructed the noise. Both experiments revealed that under most conditions, listeners could identify the shapes at better-than-chance levels. Experiment 2 also showed that the addition of a second intensity level of broadband noise randomized across trials actually improved performance. This finding suggests that listeners were likely basing their judgments on an acoustic dimension that was invariant—and was perhaps made more salient—over multiple intensities. These results add to the growing literature showing that human listeners are sensitive to sound-structuring surfaces that themselves do not produce sound.     

Duplex perception: a comparison of monosyllables and slamming doors

Duplex perception has been interpreted as revealing distinct systems for general auditory perception and speech perception. The systems yield distinct experiences of the same acoustic signal, the one conforming to the acoustic structure itself and the other to its source in vocal-tract activity. However, this interpretation has not been tested by examining whether duplex perception can be obtained for nonspeech sounds that are not plausibly perceived by a specialized system. In five experiments, we replicate some of the phenomena associated with duplex perception of speech using the sound of a slamming door. Similarities between subjects' responses to syllables and door sounds are striking enough to suggest that some conclusions in the speech literature should be tempered that (a) duplex perception is special to sounds for which there are perceptual modules and (b) duplex perception occurs because distinct systems have rendered different percepts of the same acoustic signal.     

Increasing achievement motivation and work productivity in a chronic psychiatric population

The major goal of this study was to determine if social reinforcement for behavior in a simulated work activity would increase achievement motivation, work interest, and simulated work activity production. Forty-five chronic psychiatric patients were randomly assigned to one of three groups: work sample with praise, work sample without praise, and a no-treatment control group. A 3 (between) × 2 (within) analysis of variance was run for each dependent measure, that is, achievement imagery, work interests, and simulated work production. The main effect for the interaction between trials and treatment was significant on each dependent measure. Follow-up Duncan Multiple Range Tests indicated that the praise group showed a significant improvement on each dependent measure, pre to post, as well as significantly greater improvement than the no-treatment control group and/or the work sample without praise group. These results are discussed in terms of the procedure used as a method for increasing motivation and in terms of possible generalization of results to other treatment situations.     

Persistent ERK activation maintains learning-induced long-lasting modulation of synaptic connectivity

Pyramidal neurons in the piriform cortex from olfactory-discrimination (OD) trained rats undergo synaptic modifications that last for days after learning. A particularly intriguing modification is reduced paired-pulse facilitation (PPF) in the synapses interconnecting these cells; a phenomenon thought to reflect enhanced synaptic release. The molecular machinery underlying this prolonged physiological modulation of synaptic connectivity is yet to be described. We have recently shown that extracellular regulated kinase (ERK) pathway and protein kinase C (PKC) are also required for learning-induced enhancement of intrinsic neuronal excitability. Here we examine whether these signal-transduction cascades are instrumental for the learning-induced, long-lasting PPF reduction. Days after learning completion, PD98059, a selective inhibitor of MEK, the upstream kinase of ERK, increased PPF in neurons from trained, but not in neurons from na?ve and pseudo-trained rats. Consequently, the differences in PPF between neurons from trained rats and controls were abolished. The level of activated ERK in synaptoneurosomes was significantly higher in piriform cortex samples prepared from trained rats. Notably, ERK activation revealed that PPF reduction lags behind ERK activation by 2 d. Similarly, the PKC blocker, GF-109203X, enhanced PPF in neurons from trained rats only, thus abolishing the differences between groups. Interestingly, the PKC activator, OAG, had no effect, indicating that PKC activation is required, but not sufficient for long-lasting PPF reduction. Our data show that persistent ERK activation has a key role in maintaining learning-induced PPF reduction for days. This time frame of compartmental ERK-dependent synaptic modulation suggests a novel role for ERK in cortical function.     

Postponing trauma: The dangers of telling

Surviving a major historical trauma has consequences that are difficult to live with. Survivors who remain silent are often condemned to a desiccated existence, a dried‐out life, a death in life. Survivors who speak out run an even greater risk. Telling their ghastly tale may trigger somatic consequences, psychotic episodes, or even suicide. As to the psychoanalytic cure, the free association it requires carries its own danger: negative therapeutic reaction in sometimes extreme forms. Avoidance of horror may turn into avoidance of life itself. Awful as it may seem, this avoidance of life may represent a victory over a menacing chaos. Should we as analysts accept the risk of endangering such a victory, no matter how unsatisfactory? The psychoanalytical injunction to speak out may trigger an upsurge of shame and terror. Is subjectivation always possible? This paper is about what happens when denial and splitting strategies are suspended, when ‘crypts’ are opened. Is there an analytic ‘poros’ allowing for a controlled return of affects? Is there a therapeutic solution to the problem of telling a wreckage without being caught in it? The dangers of ‘telling’ will be discussed in regard to new analytic strategies and new interpretive registers. When the ‘silent psychic sharing’ proves insufficient, some analysts go so far as to take part in the shame, share the grief, ‘lend their own psyche’, become a ‘double’ of the analysand, accept the existence of ‘sanctuaries’. To what effect?     

MAPK activation in the hippocampus in vivo is correlated with experimental setting

The mitogen-activated protein kinase (MAPK) pathway is an evolutionarily conserved signaling cascade involved in both synaptic plasticity and memory formation. Following our recent observation of translation regulation in taste learning and memory, we aimed to study MAPK-dependent translation regulation in long-term potentiation (LTP), a cellular model of learning and memory. We first analyzed ERK1/2 activation following high-frequency stimulation in the dentate gyrus (DG) of the hippocampus, in vivo. Surprisingly, our results indicate that the activation of both ERK2 and p38 was strongly affected by the order in which the DG was dissected out, but not by other experimental parameters. Specifically, we found that ERK2 and p38 phosphorylation were higher in the second than in the first dentate gyrus removed (up to 30s apart). Similar results were obtained when we isolated the 'order of removal' factor by looking at MAPK phosphorylation in rats that had not undergone any electrophysiological procedure (i.e., na?ve rats). This effect is so robust, that it probably masks the effect of LTP induction on MAPK activation. We suggest that some of the correlations found between MAPK activation and brain function in vivo may be due to cellular stress. In addition, careful experimental procedures and control are indispensable in the analysis of biochemical correlations of post-translation modifications that subserve both general neuronal function and synaptic plasticity.     

Religious Parties, Religious Political Identity, and the Cold Shoulder of Liberal Democratic Thought

Elements of the relation between religion and politics are standard themes in political theory: toleration and free exercise rights; the parameters of separation of church and state; arguments for and against constraints imposed on religious discourse by philosophic norms of public reason. But religious parties and partisanship are no part of political theory, despite contemporary interest in value pluralism and in liberal democratic theory's capacity to address multicultural, religious, and ethnic group claims. This essay argues that religious parties are missing elements in discussions of identity politics. They play an important role not just in expressing but also in constructing and mobilizing religious political identity. Political activity linked to parties is a principal way of bringing diffuse, politically unorganized groups, whose leaders are self-appointed and not regularly accountable for the way they represent co-religionists in political life, into the democratic mainstream. With political organization and especially partisanship, the fact of pluralism is made concrete for democratic purposes.