Characterizing cognition in ADHD: beyond executive dysfunction

The hypothesis that Attention-Deficit/Hyperactivity Disorder (ADHD) reflects a primary inhibitory executive function deficit has spurred a substantial literature. However, empirical findings and methodological issues challenge the etiologic primacy of inhibitory and executive deficits in ADHD. Based on accumulating evidence of increased intra-individual variability in ADHD, we reconsider executive dysfunction in light of distinctions between 'hot' and 'cool' executive function measures. We propose an integrative model that incorporates new neuroanatomical findings and emphasizes the interactions between parallel processing pathways as potential loci for dysfunction. Such a reconceptualization provides a means to transcend the limits of current models of executive dysfunction in ADHD and suggests a plan for future research on cognition grounded in neurophysiological and developmental considerations.     

Maternal depression, adult attachment, and children's emotional distress

INTRODUCTION: Our goal was to evaluate the impact of depressed mothers' marital intimacy and attachment security in romantic relationships on children's internalizing and externalizing symptoms. METHOD: Forty-six clinically depressed mothers rated attachment security, marital intimacy, and symptoms shown by their children aged 8 to 12. RESULTS: Maternal avoidance of closeness predicted increases in children's internalizing symptoms over a 6-month period. DISCUSSION: Avoidance of closeness in depressed mothers may be implicated in the development of internalizing symptoms in their children, possibly because individuals who are avoidant of closeness are poor caregivers.     

Chapters of Our Lives: Life Narratives of Midlife and Older Australian Women

A narrative approach was used to explore whether women perceive their later years as a time of loss, stability, or gain, and the explanations they give for their perceptions. Life review interviews were held with 20 married or previously married mothers aged 60–65 living in lower-income suburbs of Sydney, Australia. Participants were asked to consider their life story as a book, to divide the book into chapters, and to entitle each chapter. Two types of gain narrative accounted for 70% of the stories: one (breakouts) described gains that resulted from the womans own actions, and the other (stress relief) described gains from role changes and the passage of time. A further 20% described continuing contentment with their lives, and 10% of the accounts described later life in terms of losses. The findings suggest that one reason for the later life satisfaction regularly found by surveys of older adults may be the disappearance or diminishment of previous life stressors. As part of a planned cohort comparison, similar interviews were held with women aged 50–55 and 40–45. An additional category of ongoing stress was required to accommodate their narratives.     

The perceived vulnerability to disease scale: Cross-cultural measurement invariance and associations with fear of COVID-19 across 16 countries

Using cross-sectional data from N = 4274 young adults across 16 countries during the COVID-19 pandemic, we examined the cross-cultural measurement invariance of the perceived vulnerability to disease (PVD) scale and tested the hypothesis that the association between PVD and fear of COVID-19 is stronger under high disease threat [that is, absence of COVID-19 vaccination, living in a country with lower Human Development Index (HDI) or higher COVID-19 mortality]. Results supported a bi-factor Exploratory Structural Equation Modeling model where items loaded on a global PVD factor, and on the sub-factors of Perceived Infectability and Germ Aversion. However, cross-national invariance could only be obtained on the configural level with a reduced version of the PVD scale (PVD-r), suggesting that the concept of PVD may vary across nations. Moreover, higher PVD-r was consistently associated with greater fear of COVID-19 across all levels of disease threat, but this association was especially pronounced among individuals with a COVID-19 vaccine, and in contexts where COVID-19 mortality was high. The present research brought clarity into the dimensionality of the PVD measure, discussed its suitability and limitations for cross-cultural research, and highlighted the pandemic-related conditions under which higher PVD is most likely to go along with psychologically maladaptive outcomes, such as fear of COVID-19.     

Validation of selected MMPI-2 basic and content scales

To investigate whether some of the MMPI-2 basic and/or content scales measure the factor structure represented by the Big-Five, 288 undergraduates (178 women and 110 men), between the ages of 18 and 34 years, were administered MMPI-2 and MARS (Michill Adjective Rating Scale) which measures four factors that are conceptually similar to the first four of the Big-Five. It was hypothesized that (a) three MMPI-2 scales (basicDepression or D, contentAnxiety or ANX, and contentDepression or DEP) would be correlated with MARSUnhappiness; (b) two MMPI-2 scales (basicSocial Introversion or Si and contentSocial Discomfort or SOD) would be correlated with MARSExtraversion; (c) two MMPI-2 scales (contentAnger or ANG and contentType A Behavior or TPA) would be correlated with MARSAssertiveness; and (d) two MMPI-2 scales (contentWork Interference or WRK and supplementaryDominance or DOM) would be correlated with MARSProductive Persistence. Results corroborated the hypothesized relationships between the components of the aforementioned four dyads.     

TEACHING SELF-ADMINSTRATION OF NASOGASTRIC TUBE INSERTION TO AN ADOLESCENT WITH CROHN DISEASE

We examined the effectiveness of simulation training to teach an adolescent male with Crohn disease to self-administer nasogastric tube insertion. Nasogastric tube insertion was taught using simulation training, after which self-insertion skills were assessed. Results across skill components indicated that this subject was able to self-administer insertion of the nasogastric tube.     

Deficient inhibitory control in attention deficit hyperactivity disorder

The purpose of this study was to examine two executive control processes — response inhibition and re-engagement of responses after inhibition in children with attention deficit hyperactivity disorder (ADHD). Thirty-three children with ADHD and 22 normal control children of similar age (7 to 11 years) and mean IQ (107) were tested with the change paradigm. ADHD subgroups were defined by the context in which the ADHD symptoms predominated (in the home only; at school only; and in both, i.e., pervasive ADHD). Children with marked oppositional defiant or conduct disorder were excluded. Children with ADHD exhibited deficits in inhibitory control and in response re-engagement. Deficits were greatest in pervasive ADHD and, to a lesser extent, in those with ADHD limited to the school context. ADHD limited to the home context showed the least deficit. These results replicate an earlier study that found deficient inhibitory control in pervasive ADHD and demonstrate that the deficit in ADHD involves a second aspect of executive control.We are grateful to Anne Rhodes and Isobelle Williams for their assistance in the conduct of this research. This research was supported by grants from Health and Welfare Canada and the Medical Research Council of Canada. This paper was prepared with the assistance of Medical Publications, The Hospital for Sick Children, Toronto, Ontario.     

Antecedent reinforcement contingencies in the stimulus control of an auditory discrimination

In order to assess possible confounding of discriminative stimulus effects with those produced by the reinforcing stimulus, three groups of four rats each were trained for 45 hr on a variable-interval 1-min reinforcement program. Two groups were run on a multiple variable-interval extinction schedule in which the reinforcement stimulus (S^D) and the nonreinforcement stimulus (S^Δ) were two intensities of a 4-kHz (cps) tone separated by 40 or 10 db. The third group was run on a mixed schedule with a single intensity constantly present. The mixed-schedule animals showed no discrimination of the reinforcement program. Under the multiple schedule, the highest S^Δ rates were obtained after S^D intervals, regardless of the reinforcement availability in the S^D interval. These local rate variations in S^Δ were small in proportion to those produced by the S^D versus S^Δ intensities.