Possible antecedents and developmental implications of shame in young girls

The objectives of this study were to assess the effects of parenting style and child emotionality on the development of proneness to shame in young girls, and the mediating effect of shame on the development of adjustment problems. Eighty‐eight girls were assessed twice, at 3 and 5 years of age, along with their mothers and fathers. Shame was assessed by observations (reactions to failure and criticism); parenting style and child emotions (fearfulness, sadness, anger) were measured using parent reports; and adjustment problems were assessed by parent and teacher reports. Girls were more likely to show shame at age 5 when both their mothers and fathers had been relatively authoritarian at age 3; their emotional dispositions did not have any direct longitudinal effects on shame. Authoritarian parenting predicted subsequent internalizing problems as assessed by teachers, but there was no evidence for a mediational effect of shame. Copyright © 2003 John Wiley & Sons, Ltd.     

Hyperactivity and Learning Deficits in Transgenic Mice Bearing a Human Mutant Thyroid Hormone β1 Receptor Gene

Resistance to thyroid hormone (RTH) is a human syndrome mapped to the thyroid receptor β (TRβ) gene on chromosome 3, representing a mutation of the ligandbinding domain of the TRβ gene. The syndrome is characterized by reduced tissue responsiveness to thyroid hormone and elevated serum levels of thyroid hormones. A common behavioral phenotype associated with RTH is attention deficit hyperactivity disorder (ADHD). To test the hypothesis that RTH produces attention deficits and/or hyperactivity, transgenic mice expressing a mutant TRβ gene were generated. The present experiment tested RTH transgenic mice from the PV kindred on behavioral tasks relevant to the primary features of ADHD: hyperactivity, sustained attention (vigilance), learning, and impulsivity. Male transgenic mice showed elevated locomotor activity in an open field compared to male wild-type littermate controls. Both male and female transgenic mice exhibited impaired learning of an autoshaping task, compared to wild-type controls. On a vigilance task in an operant chamber, there were no differences between transgenics and controls on the proportion of hits, response latency, or duration of stimulus tolerated. On an operant go/no-go task measuring sustained attention and impulsivity, there were no differences between controls and transgenics. These results indicate that transgenic mice bearing a mutant human TRβ gene demonstrate several behavioral characteristics of ADHD and may serve a valuable heuristic role in elucidating possible candidate genes in converging pathways for other causes of ADHD.     

On microprocessor-based computers

Economical microprocessor-based computers have been recently developed by Motorola and Control Logic, Inc. Apparently, in response to the price competition, DEC has introduced the PDP-8/A, incorporating the memory characteristics of the microprocessor-based computers. Relative to older minicomputers, the microprocessor-based systems and the PDP-8/A “miniprocessor” require more time to execute an experimentally useful task. However, their real-time operating characteristics would appear to be sufficient for on-line use in behavioral control and data acquisition. The PDP-8/A’s compatibility with older models of the PDP-8 series enables it to use previously developed software, but, for purposes of software development, the microprocessor systems offer a more powerful architecture and instruction set.     

Generalization and discrimination as a function of the SD — SΔ intensity difference

Three groups of four rats were trained on an auditory-intensity discrimination for 21 days. The S^D-S^Δ intensity difference for Group I was 10 db; for Group II, 20 db; and for Group III, 30 db. Following the initial discrimination training, the animals were tested for generalization of the bar-press response to seven novel S^Δ's which were presented intermingled with the original S^D and S^Δ values. Conclusions: (1.) The amount of simple discrimination training required to obtain fairly stable differences in S^D and S^Δ responding is an inverse function of the magnitude of the stimulus difference between S^D and S^Δ. (2.) Generalization gradients obtained immediately following simple discrimination training exhibit a maximum displaced from S^D in a direction also away from S^Δ. (3.) Gradients obtained following continued exposure to the multivalued S^Δ situation show a fairly stable maximum at the S^D value. (4.) Although the gradients tend to fall off systematically on either side of the continuum as distance from S^D is increased, they decrease most rapidly on the S^Δ limb of the gradient.