Understanding the Progression from Early Alcohol Use Experimentation to Alcohol Use Disorder: Testing Vulnerability by Experience Interactions Using a Two-Part Latent Growth Curve Model

Most adolescents experiment with alcohol, but a smaller percentage advance to heavy alcohol use (AU) and AU disorder (AUD). Understanding for whom and how early risk leads to AUD is of interest to prevention, treatment, and etiology of AUD. Informed by developmental and behavioral neuroscience theory, the current study tested whether temperament (effortful control, surgency, and negative affect), peer AU (multi-reporter), and AU with parents’ permission interacted to distinguish youth who experiment with alcohol from those who escalate to AUD. Community adolescents (N?=?765, 53% female) were assessed annually for seven years (M_age?=?11.8, range: 10–13 at Year 1; M_age?=?18.7; range?=?17–20 at year 7). Temperament by early experience interactions were expected to predict amount of AU. Amount of AU was expected to mediate the relationship between the interactions and AUD symptoms (assessed at Years 3 and 7, M_age?=?13.8 and 18.7) above and beyond a range of confounds (e.g., problem behavior and parental AU and AUD). Supporting hypotheses, effortful control and surgency interacted with AU with parents’ permission and peer AU, respectively, to predict higher amount of AU (R²?=?0.47) and AUD symptoms (R²?=?0.03). Results support developmental and behavioral neuroscience theory. High surgency and low effortful control in conjunction with peer AU and AU with parents’ permission were associated with large effects on AU and moderate mediated effects through AU to AUD. AU with parents’ permission was risky at low and high effortful control and protective when peers used alcohol.

     

Reading as a source of knowledge

Synthese - This paper argues that reading is a source of knowledge. Epistemologists have virtually ignored reading as a source of knowledge. This paper argues, first, that reading is not to be...     

Yes,they can! Efficient physical effort mobilization according to task difficulty in schizophrenia

The current literature has largely highlighted a deficit of effort-based decision-making for reward in schizophrenia. However, not all studies have dissociated effort from reward, while other studies emphasize that difficulty is the main determinant of effort rather than reward. In this study, 33 individuals with schizophrenia and 32 healthy controls were recruited to perform a decision-making isometric force task. According to motivational intensity theory, task difficulty (i.e., required force) but not reward was manipulated from easy to impossible. Accuracy between force exerted and force required, and choice to perform a task or not were our effort measures. Clinical variables including depression, defeatist beliefs, and apathy were assessed. Our results demonstrated that the schizophrenia group chose to perform easy, moderate, and difficult tasks and exerted the necessary effort to succeed similarly to the non-clinical group. No association between effort and clinical variables was found. Our findings provide new understandings related to effort mechanisms in schizophrenia.

     

Nonsuicidal Self-injury,Suicide Planning,and Suicide Attempts Among High-risk Adolescents Prior to Psychiatric Hospitalization

Research on Child and Adolescent Psychopathology - The purpose of this study was to understand the trajectories of nonsuicidal self-injury (NSSI) and suicide plans (SP) in the 90 days...