Minding the Genes: a Multidisciplinary Approach towards Genetic Assessment of Cardiovascular Disease

Genetic assessment for inherited cardiovascular disease (CVD) is increasingly available, due in part to rapid innovations in genetic sequencing technologies. While genetic testing is aimed at reducing uncertainty, it also produces awareness of potential medical conditions and can leave patients feeling uncertain about their risk, especially if there are ambiguous results. This uncertainty can produce psychological distress for patients and their families undergoing the assessment process. Additionally, patients may experience psychological distress related to living with inherited CVD. In order to more effectively manage the psychosocial challenges related to genetic assessment for CVD, a multidisciplinary model expanded to include psychologists and other allied health professionals is outlined. A case study is provided to illustrate how psychological distress can manifest in a patient living with inherited CVD, as well as proposed psychological management of this patient. Finally, a guide for genetic counselors is provided to aid in identifying and managing common psychological reactions to genetic assessment for CVD.     

Grit in adolescence is protective of late-life cognition: non-cognitive factors and cognitive reserve

Various psychological assets have been shown to protect against late-life cognitive impairment by promoting cognitive reserve. While factors such as educational attainment and IQ are well-established contributors to cognitive reserve, noncognitive factors, such as grit, have not been studied in this regard. We examined the contribution of adolescent grit, indexed by high school class rank controlling for IQ, to late-life cognition and its decline among approximately 4000 participants in the Wisconsin Longitudinal Study, a random sample of high school graduates followed from 1957 to 2011. Adolescent grit significantly predicted both immediate and delayed memory at ages 64 and 71, over and above the contribution of IQ. While the relative contributions of IQ and grit to immediate memory were comparable, grit was a stronger predictor of delayed memory. Cognitive reserve has noncognitive, as well as cognitive, components.     

Scientist-practitioner family therapists, postmodern medical practitioners and expert parents: second-order change in the Eating Disorders Program at The Children's Hospital at Westmead

The Maudsley model of family-based treatment for anorexia integrates a variety of schools of family therapy, and has been developed and supported by a number of randomized controlled trials. In this paper we will describe the systemic organizational changes that have occurred as a result of the inclusion of this model in the Eating Disorders Program at The Children's Hospital at Westmead over an eighteen-month period, including a process of mutual influence between medical practitioners and family therapists. These changes have contributed towards a dramatic improvement in clinical outcomes including a significant drop in readmission rates to hospital.     

Conscience,conscientious objections,and medicine

Theoretical Medicine and Bioethics - To inform the ongoing discussion of whether claims of conscientious objection allow medical professionals to refuse to perform tasks that would otherwise be...     

Personality,the Theory of Planned Behavior,and Exercise: A Unique Role for Extroversion's Activity Facet1

The primary purpose of this study was to determine if the theory of planned behavior (TPB) mediated the relationship between selected personality traits (i.e., extroversion, neuroticism, and conscientiousness) and exercise behavior using structural equation modeling. Based on previous research, it was hypothesized that extroversion (E) would have a significant direct effect on exercise behavior while controlling for the TPB. A secondary purpose was to explore whether the facets of these personality domains had significant effects on TPB constructs or exercise behavior while controlling for the general personality domains. Female undergraduate students (N= 301) completed measures of the TPB, the Five‐Factor model of personality, and a 1‐month exercise behavior follow‐up. Model 1 resulted in a direct effect of E on exercise behavior. Model 2 suggested a significantly better fit when direct effects of E's activity facet were freed for estimation. Moreover, freeing these effects rendered the effects of general E nonsignificant. It was concluded that the direct effect of E on exercise behavior found in previous research might be explained entirely by the activity facet of E.     

The influence of divided attention on holistic face perception.

There is evidence that upright, but not inverted, faces are encoded holistically. The holistic coding of faces was examined in four experiments by manipulating the attention allocated to target faces. In Experiment 1, participants in a divided attention condition were asked to match two upright flanker faces while encoding a centrally presented upright target face. Although holistic coding was evident in the full attention conditions, dividing attention disrupted holistic coding of target faces. In Experiment 2, we found that while matching upright flanker faces disrupted holistic coding, matching inverted flanker faces did not. Experiment 3 demonstrated that the differential effects of flanker orientation were not due to participants taking longer to match upright, than inverted, flanker faces. In Experiment 4, we found that matching fractured faces had an intermediate effect to that of matching upright and inverted flankers, on the holistic coding of the target faces. The findings emphasize the differences in processing of upright, fractured and inverted faces and suggest that there are limitations in the number of faces that can be holistically coded in a brief time.     

Are average and symmetric faces attractive to infants? Discrimination and looking preferences

Young infants prefer to look at faces that adults find attractive, suggesting a biological basis for some face preferences. However, the basis for infant preferences is not known. Adults find average and symmetric faces attractive. We examined whether 5-8-month-old infants discriminate between different levels of averageness and symmetry in faces, and whether they prefer to look at faces with higher levels of these traits. Each infant saw 24 pairs of female faces. Each pair consisted of two versions of the same face differing either in averageness (12 pairs) or symmetry (12 pairs). Data from the mothers confirmed that adults preferred the more average and more symmetric versions in each pair. The infants were sensitive to differences in both averageness and symmetry, but showed no looking preference for the more average or more symmetric versions. On the contrary, longest looks were significantly longer for the less average versions, and both longest looks and first looks were marginally longer for the less symmetric versions. Mean looking times were also longer for the less average and less symmetric versions, but those differences were not significant. We suggest that the infant looking behaviour may reflect a novelty preference rather than an aesthetic preference.