Behavioral characterization of a transection of dorsal CA3 subcortical efferents: comparison with scopolamine and physostigmine infusions into dorsal CA3

Cholinergic projections from the medial septum and diagonal band of Broca into the hippocampus have long been implicated in learning and memory. Projections from CA3 to neurons in the medial septum and the diagonal band of Broca have been anatomically characterized. The present experiments were designed to evaluate interactions between the dorsal CA3 subcortical efferents and the cholinergic efferents from the medial septum and diagonal band of Broca for spatial and nonspatial (visual object) novelty detection in the rat. In Experiment 1, physostigmine and scopolamine (both 0.4 microL at 30 microM) were infused into dorsal CA3 and animals were tested on a spatial and nonspatial (visual object) novelty detection paradigm. Scopolamine infusions into dorsal CA3 caused deficits for both spatial and nonspatial (visual object) novelty detection. Physostigmine infusions into dorsal CA3 enhanced both spatial and nonspatial (visual object) novelty detection. These data support models proposing that acetylcholine may control the dynamics for encoding, consolidation, and retrieval in the hippocampus. In Experiment 2, a selective transection of dorsal CA3 efferents in the fimbria resulted in deficits for spatial and nonspatial (visual object) novelty detection. These deficits were similar to the deficits caused by scopolamine infusions into dorsal CA3. These data demonstrate that dorsal CA3 and the medial septum/diagonal band of Broca interact, and that dorsal CA3 influences cholinergic inputs into the hippocampus to facilitate encoding.     

Malingering on the Personality Assessment Inventory: identification of specific feigned disorders

Profile validity is a primary consideration in the clinical assessment of psychopathology. Several indicators of negative impression management have been developed for the Personality Assessment Inventory (PAI; Morey, 1991) that can both indicate its presence and help differentiate effortful negative distortion from distortion arising from cognitive sets associated with psychopathology. In this study, we tested a method designed to delineate the specific Clinical scales relevant for interpretation of deliberately feigned disorders. We used associations between the Negative Impression Management (NIM) scale and Clinical scales in the normative standardization sample to derive NIM predicted scale scores in a regression framework. We contrasted these predicted scores with observed scores on Clinical scales to yield NIM predicted discrepancies hypothesized to identify those Clinical scales most salient for the interpretation of negative distortion. We found this method to be effective in identifying particular distortion on the relevant scales for individuals attempting to feign 3 specific diagnoses (major depressive disorder, generalized anxiety disorder, and schizophrenia).     

Comparing measures of cognitive bias relating to eating behaviour

Consumption of and/or abstinence from substances with a high reward value (e.g. heroin, marijuana, alcohol, nicotine, certain foods) are associated with cognitive biases for information related to the substance. Such cognitive biases are important since they may contribute to difficulties in controlling intake of the substance. We examine cognitive biases for stimuli related to food. For the first time, we concurrently employ and compare five conceptually distinct measures of cognitive bias (dot probe, emotional Stroop, recognition, EAST, explicit attitudes). Contrary to expectations from current theory, the relation between the cognitive measures was weak and evident only in certain subsets of the population sample, as defined by gender and emotional‐, restrained‐ and external‐eating characteristics of our participants. We discuss some methodological implications of our findings. Copyright © 2008 John Wiley & Sons, Ltd.     

Chicks prefer to peck at insect-like elongated stimuli moving in a direction orthogonal to their longer axis

Spontaneous preferences towards possible prey have been little investigated using targets in motion. Preferences of domestic chicks (Gallus gallus) to peck at video-images of stimuli representing live insects moving along their longer body axis (i.e. “forwards”) or along the shorter body axis (i.e. “sideways”) were investigated. Chicks presented with both types of stimulus displayed a significant preference for pecking at stimuli moving sideways. This preference was already present on day 1 post-hatching, and it strengthened on day 6 for those chicks that had experienced pecking at live insects. Head angles used to fixate the stimuli prior to pecking were also analysed and were consistent (i.e. 30°–35° and 60°–65°) with those reported for fixation of non-edible targets (larger stimuli at a distance). In a first control experiment the same video-presented stimuli were used but the insect’s legs were removed to reduce flickering. In a second control experiment, paper-printed images of the whole insect were used. In both cases, the sideways direction of movement was clearly preferred. Overall, our data show that chicks have a spontaneous preference to peck at video-images resembling live insects moving along their shorter body axis. Sideways movement may constitute a crucial signal attracting chicks’ attention and enhancing predatory responses possibly because of stronger stimulation of motion detectors.     

Affective synchrony: individual differences in mixed emotions

Most models of affect suggest either inverse or null associations between positivity and negativity. Recent work has highlighted situations that sometimes lead to mixed positive-negative affect. Focusing on the counterpart to these situational factors, the authors explore the individual-difference tendency toward mixed emotions, which they term affective synchrony. In five studies, the authors show that some individuals demonstrate affective synchrony (overlapping experience of positive and negative moods), others a-synchrony (positive and negative mood that fluctuate independently), and still others de-synchrony (positive and negative moods that function as bipolar opposites). These tendencies are stable over time within persons, vary broadly across individuals, and are associated with individual differences in cognitive representation of self and of emotions.     

"It Could Be Us!": Cognitive and Social Psychological Factors in UK National Lottery Play

This study examines the cognitive and social psychological factors underlying UK National Lottery play. A total of 384 respondents were asked about their own lottery playing behaviours, their knowledge of lottery odds and their beliefs about the role of skill, chance, luck and optimism in lottery play. Using hypothetical scenarios, respondents were also asked to rate the likelihood of winning the lottery jackpot (matching all six numbers) with number combinations reflecting different levels of apparent randomness, previous matches, near misses and prize size manipulations. Frequency of lottery play was found to be positively correlated with age, income, Instants scratchcard play, gambling on horse/greyhound racing, the football pools, and bingo as well as with beliefs about skill, luck and optimism. Frequency of lottery play was negatively correlated with general education and estimate of relative win likelihoods based on the perceived randomness of number combinations. Planned contrasts revealed that compared to individual (non‐syndicate) players, syndicate lottery players played more regularly and gambled more on the football pools. Results are discussed in the light of current cognitive theories surrounding the misperception of probability and their relation to lottery play and in the need for future models to recognise the social factors inherent in syndicate‐based lottery participation.     

Improving Decision Making by Means of Dissent1

Antidotes to problems associated with uniformity of viewpoints have generally involved dissent in one form or another (Katzenstein, 1996), one being “devil's advocate.” Research on authentic dissent has documented additional advantages in that it stimulates divergent and original thought (Nemeth, 1995). In this study, authentic disscnt was compared with devil's advocate and with no dissent. Findings indicate that authentic dissent was superior in (a) stimulating a greater proportion of original thoughts, (b) considering the opposite position, and (c) direct attitude change. Devil's advocate was found to stimulate cognitive boistcring of the initial position, thus raising concerns about the unintended consequences of techniques such as devil's advocate and the subtle task facing attempts to foster original thought and yet maintain cohesion.