Developmental regression in autism spectrum disorders

The occurrence of developmental regression in autism is one of the more puzzling features of this disorder. Although several studies have documented the validity of parental reports of regression using home videos, accumulating data suggest that most children who demonstrate regression also demonstrated previous, subtle, developmental differences. Counter to clinical intuition, the earlier development of social, language, and attachment behaviors followed by regression does not seem to support later recovery of skills or better developmental outcomes compared to children who never had speech or typical social responsivity. In fact, this regressive group may have somewhat greater developmental impairment than the nonregressive group, though the two groups do not appear to present different behavioral phenotypes. Although autism is not the only condition in which regression occurs, it appears to be the most frequent condition. Other disorders that demonstrate an early regression with no known etiology include total blindness from birth and childhood disintegrative disorder, both of which demonstrate behavioral relations to autism. In addition, two biological conditions with known etiologies also involve regression with some behaviors resembling autism behavioral phenotype: Rett syndrome (a genetic disorder; see Glaze, this issue) and Landau-Kleffner syndrome (see McVicar and Shinnar, this issue), which involves a seizure disorder.     

Contraction bias in memorial quantifying judgment: does it come from a stable compressed memory representation or a dynamic adaptation process?

A common response bias in psychophysical judgments is regression toward the mean (overestimation of small and underestimation of large values, or the response contraction bias). The same bias is observed in magnitude estimation from memorized quantities. Participants estimated alphabetic interval distances between 2 letters for different levels of interletter distances. The underestimated and overestimated values and the point of least error changed, depending on the level of alphabetic distances judged; furthermore, their estimation showed a progressively increasing tendency toward the mean, rendering the estimation progressively less accurate as the estimation task was repeated. We conclude that the regression toward the mean in memorial quantifying judgment derives from a cognitive adaptation process rather than from a permanent, compressed memory representation of the stimuli. Two opposing views on the adaptive meaning of this judgment bias are discussed.     

The anatomy of suicidology: a psychological science perspective on the status of suicide research. 2002 Shneidman Award Address

Suicidologists have made tremendous strides in advancing the knowledge of correlates of completed suicide and nonfatal suicidal behavior since the early 1960s. In order to move beyond the simple identification of risk factors, however, scientific suicidology needs to give greater attention to the critical role of theory in guiding inquiry and advancing the understanding of suicidal behaviors. In this article I argue the importance of theoretical grounding from the perspective of psychological science, provide examples of this perspective from my work, and discuss their implications for future research in the field.     

Mental Health and Incarcerated Youth. I: Prevalence and Nature of Psychopathology

The incarceration of mentally ill youth is a serious problem not receiving the same attention as in adults. In this study, we examine the prevalence of psychopathology and level of behavioral symptomatology in incarcerated youth versus youth receiving community mental health services or hospitalization. We randomly recruited youth from middle South Carolina served by a local CMHC (n = 60), youth served by the state adolescent inpatient program (n = 50), and youth in the S.C. Dept. of Juvenile Justice facilities from the same region (n = 75). We used the DISC-PC 2.3 to evaluate DSM-III-R diagnoses and the CBCL and YSR to evaluate behavioral symptomatology. On the DISC, incarcerated youth had significantly higher mean number of diagnoses and symptoms than CMHC youth, but lower numbers than hospitalized youth. Level of caseness (at least one diagnosis) was 86% in hospital youth, 72% in incarcerated youth, and 60% in CMHC youth. The groups differed in CBCL mean total T, internalizing T, and externalizing T scores as well as mean YSR internalizing T scores. Our results indicate the comparability in level of psychopathology in incarcerated and community-treated populations of youth, and the need to develop diversionary programs to prevent the entry of such youth into the juvenile justice system.     

Book reviews

Campbell, B. A., Hayne, H., & Richardson, R. (Eds.) (1992). Attention and information processing in infants and adults. Perspectives from human and animal research. Hove: Lawrence Erlbaum Associates. Pp. viii + 360. ISBN 0-8058-0782-9. £54.95 (Hbk).

McFarland, D. (1993). Animal behaviour: Psychobiology, ethology and evolution (2nd ed.). Harlow: Longrnan Scientific and Technical. Pp. xiv + 585. ISBN 0-582-06721-9. £23.99 (Pbk).

Ward, J. P., & Hopkins, W.D. (Eds.) (1993). Primate laterality: Current behavioral evidence of primate asymmetries. New York/Berlin: Springer-Verlag. Pp. xii + 356. ISBN 0-387-97961-1 13-540-97961-1. £34.50 (Pbk).

Zentall, T. R. (Ed.). (1993). Animal cognition. A tribute to Donafd A. Riley. Hillsdale, NJ: Lawrence Erlbaum Associates, Inc. Pp. xiv + 369. ISBN 0-8058-1 184-2. £22.95 (Pbk); ISBN 0-8058-1 183-4. £53.50 (Hbk).

Roitblatt, H. L., Herman, L. M., & Nachtigall, P.E. (Eds.) (1993). Language and communication. Comparative perspectives. Hillsdale, NJ : Lawrence Erlbaum Associates, Inc. Pp. xvi + 502. ISBN 0-8058-0947-3. £26.95 (Pbk); ISBN 0-8058-0946-5. £59.95 (Hbk).

Bradshaw, J. L, & Rogers, L.J. (1993). The evolution of lateral asymmetries, language, roo1 use, and intellect. San Diego, CA: Academic Press. Pp. xiii + 463. ISBN 0-12-124560-8. £58.00 (Hbk).

Ten Cate, C., Slater, P. J. B., & Kruijt, J. P. (Eds.) (1993). Song learning and imprinting. An inquiry into mechanisms of behavioural development. Amsterdam: Netherlands Zoology Society. Pp. 234. £13.00 (Pbk).     

Imitation from 12 to 24 months in autism and typical development: a longitudinal Rasch analysis

The development of imitation during the second year of life plays an important role in domains of sociocognitive development such as language and social learning. Deficits in imitation ability in persons with autism spectrum disorder (ASD) from toddlerhood into adulthood have also been repeatedly documented, raising the possibility that early disruptions in imitation contribute to the onset of ASD and the deficits in language and social interaction that define the disorder. This study prospectively examined the development of imitation between 12 and 24 months of age in 154 infants at familial risk for ASD and 78 typically developing infants who were all later assessed at 36 months for ASD or other developmental delays. The study established a developmental measure of imitation ability and examined group differences over time, using an analytic Rasch measurement model. Results revealed a unidimensional latent construct of imitation and verified a reliable sequence of imitation skills that was invariant over time for all outcome groups. Results also showed that all groups displayed similar significant linear increases in imitation ability between 12 and 24 months and that these increases were related to individual growth in both expressive language and ratings of social engagement but not in fine motor development. The group of children who developed ASD by age 3 years exhibited delayed imitation development compared with the low-risk typical outcome group across all time-points, but were indistinguishable from other high-risk infants who showed other cognitive delays not related to ASD.     

Frequent false hearing by older adults: the role of age differences in metacognition

In two experiments testing age differences in the subjective experience of listening, which we call meta-audition, young and older adults were first trained to learn pairs of semantic associates. Following training, both groups were tested on identification of words presented in noise, with the critical manipulation being whether the target item was congruent, incongruent, or neutral with respect to prior training. Results of both experiments revealed that older adults compared to young adults were more prone to "false hearing," defined as mistaken high confidence in the accuracy of perception when a spoken word had been misperceived. These results were obtained even when performance was equated across age groups on control items by reducing the noise level for older adults. Such false hearing is shown to reflect older adults' heavier reliance on context. Findings suggest that older adults' greater ability to benefit from semantic context reflects their bias to respond consistently with the context, rather than their greater skill in using context. Procedures employed are unique in measuring the subjective experience of hearing as well as its accuracy. Both theoretical and applied implications of the findings are discussed. Convergence of results with those showing higher false memory, and false seeing are interpreted as showing that older adults are less able to constrain their processing in ways that are optimal for performance of a current task. That lessened constraint may be associated with decline in frontal-lobe functioning.