The paraventricular nucleus of the hypothalamus (PVN) has been implicated in several aspects of cardiovascular control. Stimulation of the PVN evokes changes in blood pressure and heart rate. Additionally, this brain area is connected to several limbic structures implicated in behavioral control, as well as to forebrain and brainstem structures involved in cardiovascular control. This evidence indicates that the PVN may modulate cardiovascular correlates of behavioral responses to stressful stimuli. Acute restraint is an unavoidable stressor that evokes marked and sustained cardiovascular changes, which are characterized by elevated mean arterial pressure (MAP) and an intense heart rate (HR) increase. We report on the effect of inhibition of PVN synapses on MAP and HR responses evoked by acute restraint in rats. Bilateral microinjection of the nonspecific synaptic blocker cobalt (CoCl(2), 1 mM/100 nl) into the PVN did not change the HR response or the initial peak of the MAP response to restraint stress, but reduced the area under the curve of the MAP response. Moreover, bilateral microinjection of cobalt in areas surrounding the PVN did not change the cardiovascular response to restraint. These results indicate that synapses in the PVN are involved in the neural pathway that controls blood pressure changes evoked by restraint. 相似文献
This study aimed to examine the psychometric properties of the Youth Psychopathic Traits Inventory - Short version (YPI-S) among a mixed-gender sample of 782 Portuguese youth (M = 15.87 years; SD = 1.72) collected in a school context. Exploratory and confirmatory factor analysis offered support for the expected 3-factor structure. Partial cross-gender measurement invariance and cross-sample measurement invariance of the YPI-S using a forensic sample of institutionalized males was established. The Portuguese version of the YPI-S showed adequate psychometric properties in terms of internal consistency, mean inter-item correlation, corrected item-total correlation, convergent validity, and discriminant validity. In support for criterion-related validity, the YPI-S also showed statistically significant associations with self-reported conduct disorder symptoms, alcohol abuse, and drug use. In terms of known-groups validity, males from the school sample scored lower than males from the forensic sample and higher than females from the school sample. The YPI-S seems to be a valuable brief and psychometrically reliable and valid self-report measure, which can be used to assess psychopathic traits in diverse samples of youth. 相似文献
Count data are commonly assumed to have a Poisson distribution, especially when there is no diagnostic procedure for checking this assumption. However, count data rarely fit the restrictive assumptions of the Poisson distribution. The violation of much of such assumptions commonly results in overdispersion, which invalidates the Poisson distribution. Undetected overdispersion may entail important misleading inferences, so its detection is essential. In this study, different overdispersion diagnostic tests are evaluated through two simulation studies. In Exp. 1, the nominal error rate is compared under different sample sizes and lamda conditions. Analysis shows a remarkable performance of the chi2 df test. In Exp. 2 and 3, statistical power is compared under different sample sizes, lamda, and overdispersion conditions. Chi2 and LR tests provide the highest statistical power. 相似文献
The aim of this study was to test whether honeybees develop reward expectations. In our experiment, bees first learned to associate colors with a sugar reward in a setting closely resembling a natural foraging situation. We then evaluated whether and how the sequence of the animals’ experiences with different reward magnitudes changed their later behavior in the absence of reinforcement and within an otherwise similar context. We found that the bees that had experienced increasing reward magnitudes during training assigned more time to flower inspection 24 and 48 h after training. Our design and behavioral measurements allowed us to uncouple the signal learning and the nutritional aspects of foraging from the effects of subjective reward values. We thus found that the animals behaved differently neither because they had more strongly associated the related predicting signals nor because they were fed more or faster. Our results document for the first time that honeybees develop long-term expectations of reward; these expectations can guide their foraging behavior after a relatively long pause and in the absence of reinforcement, and further experiments will aim toward an elucidation of the neural mechanisms involved in this form of learning. 相似文献
AbstractTo evaluate whether frequent interactive tablet-use at preschool age is associated with improved fine motor skills and to describe tablet-use in young children. Cross-sectional study with 78 children, aged 24–42?months: group 1 with previous frequent tablet-use exposure (n?=?26), group 2 without previous tablet-use exposure (n?=?52). Fine motor skills were evaluated with the Bayley-III. Socioeconomic data and home environment quality were similar in both groups. Fine motor skills of group 1 were better than those of group 2 (p?=?0.013). Most participating children carried out passive and active tablet activities, usually accompanied by parents, not exceeding time recommendations for young age. We observed a difference in fine motor skills in young children slightly favoring those with tablet-use experience. 相似文献
Previous research has shown that children with autism spectrum disorder (ASD) can categorize visual stimuli without direct training when they can also tact these stimuli using a common name and behave as listeners in relation to this name. However, children usually learn to assign objects specific names prior to learning the category to which they belong. The current study replicated previous research and evaluated whether multiple-tact training would establish visual categorization (measured by a picture sorting test) and listener behavior. We used a nonconcurrent multiple baseline design across 2 children with autism spectrum disorder. After multiple-tact training, we assessed whether participants would visually categorize stimuli based on their common category name. Both participants categorized and engaged in the corresponding listener behavior. 相似文献
Although psychopathy has historically been associated with a lack of emotion, recent research has suggested that psychopathy may represent a tendency to externalize the experience of unpleasant emotions, including shame, which could be seen as an adaptive strategy within an evolutionary framework. However, more empirical research is needed to build on this argument. This study tested a novel evolutionary-based model involving pathways associating the impact of harsh rearing experiences (warmth and safeness experiences and traumatic shameful experiences) with psychopathic traits as well as the indirect effects of external shame and shame coping strategies in this association. This study also tested the invariance of this model across gender. A youth community sample (N = 703; 58.9% girls) completed self-report questionnaires on the impact of harsh rearing experiences, external shame, shame coping strategies, and psychopathic traits. The results suggested that the impact of harsh rearing experiences was directly and indirectly (through external shame and shame coping strategies) associated with psychopathic traits. The model partially explained the endorsement of psychopathic traits in boys and girls, although gender differences were found in some of the pathways. These findings offer support for conceptualizing psychopathic traits as an adaptive strategy to cope with the impact of harsh rearing experiences, opening new perspectives for prevention and treatment.