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Ashley N. Tomlinson Debra Skinner Denise L. Perry Sarah R. Scollon Myra I. Roche Barbara A. Bernhardt 《Journal of genetic counseling》2016,25(1):62-72
As the use of genomic technology has expanded in research and clinical settings, issues surrounding informed consent for genome and exome sequencing have surfaced. Despite the importance of informed consent, little is known about the specific challenges that professionals encounter when consenting patients or research participants for genomic sequencing. We interviewed 29 genetic counselors and research coordinators with considerable experience obtaining informed consent for genomic sequencing to understand their experiences and perspectives. As part of this interview, 24 interviewees discussed an informed consent case they found particularly memorable or challenging. We analyzed these case examples to determine the primary issue or challenge represented by each case. Challenges fell into two domains: participant understanding, and facilitating decisions about testing or research participation. Challenges related to participant understanding included varying levels of general and genomic literacy, difficulty managing participant expectations, and contextual factors that impeded participant understanding. Challenges related to facilitating decision-making included complicated family dynamics such as disagreement or coercion, situations in which it was unclear whether sequencing research would be a good use of participant time or resources, and situations in which the professional experienced disagreement or discomfort with participant decisions. The issues highlighted in these case examples are instructive in preparing genetics professionals to obtain informed consent for genomic sequencing. 相似文献
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Dylan Colbert Ian Tyndall Bryan Roche Sarah Cassidy 《Journal of Behavioral Education》2018,27(4):509-531
A burgeoning research stream supports the efficacy of a novel behavior-analytic intervention, known as SMART training, in raising general intelligence by training a set of crucial cognitive skills, referred to as relational skills. A sample of Irish secondary school students (n?=?26) was divided into two IQ matched groups, with the experimental group receiving 12 weeks of SMART training delivered in bi-weekly 45-min sessions. WASI IQ assessments were administered at baseline and follow-up to all participants by blind testers. For each of the three WASI IQ indices and the four IQ subtests, significant follow-up rises were found for the experimental group only. Analyses of variance indicated a significant effect of training on Verbal IQ, Matrix Reasoning and Vocabulary scores. Results lend further support for the efficacy of the SMART training program in enhancing intellectual skills. 相似文献
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Laura M. Morett Jennifer M. Roche Scott H. Fraundorf James C. McPartland 《Cognitive Science》2020,44(10):e12912
We investigated how two cues to contrast—beat gesture and contrastive pitch accenting—affect comprehenders' cognitive load during processing of spoken referring expressions. In two visual-world experiments, we orthogonally manipulated the presence of these cues and their felicity, or fit, with the local (sentence-level) referential context in critical referring expressions while comprehenders' task-evoked pupillary responses (TEPRs) were examined. In Experiment 1, beat gesture and contrastive accenting always matched the referential context of filler referring expressions and were therefore relatively felicitous on the global (experiment) level, whereas in Experiment 2, beat gesture and contrastive accenting never fit the referential context of filler referring expressions and were therefore infelicitous on the global level. The results revealed that both beat gesture and contrastive accenting increased comprehenders' cognitive load. For beat gesture, this increase in cognitive load was driven by both local and global infelicity. For contrastive accenting, this increase in cognitive load was unaffected when cues were globally felicitous but exacerbated when cues were globally infelicitous. Together, these results suggest that comprehenders' cognitive resources are taxed by processing infelicitous use of beat gesture and contrastive accenting to convey contrast on both the local and global levels. 相似文献
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Clarisse Roche 《Sport, Ethics and Philosophy》2020,14(3):320-338
ABSTRACT For the past few decades a concern with heritage in the countries of the Arab Gulf has led to the reclamation of the purebred Arabian horse as one of the iconic animals of the Bedouin identity and to developing a thriving horse breeding industry in the region. While stud farms and equestrian sport events are intended to reinforce the Arabian identity of the breed, a closer look at its history demonstrate in fact the complexity of its identity. The complexity of cultural transfers with respect to horse breeding between the East and the West from the Early Modern period on, highlights the connected history of both the Arabian horses and the Thoroughbreds, and the ongoing cultural re-appropriation of both breeds as ‘native’ to the Arabian Peninsula. 相似文献