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Rino Rumiati Roberto Nicoletti Remo Job 《The Quarterly Journal of Experimental Psychology Section A: Human Experimental Psychology》1989,41(1):167-181
The experiments reported in this paper were designed to test how global and local information are processed by the memory system. When subjects are required to match a given letter with either a previously presented large capital letter or the small capital letters comprising it, (1) responses to the global level (i.e. the big letter) are faster than responses to the local level (i.e. the small letters), and (2) responses to the latter level only are affected by the consistency between the large and the small letters (Experiment 2), a pattern similar to that obtained in perception (Experiment 1). Such results obtain when subjects are required to attend to only one level with a short ISI between the first and second stimulus, but not when a longer ISI is used (Experiment 5) or when subjects are required to attend to both levels at the same time (Experiments 3 and 4). The results are discussed in the light of a model that postulates a temporal precedence of the global information over the local one at the perceptual level. 相似文献
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Two mutations preventing PDZ-protein interactions of GluR1 have opposite effects on synaptic plasticity 下载免费PDF全文
Boehm J Ehrlich I Hsieh H Malinow R 《Learning & memory (Cold Spring Harbor, N.Y.)》2006,13(5):562-565
The regulated trafficking of GluR1 contributes significantly to synaptic plasticity, but studies addressing the function of the GluR1 C-terminal PDZ-ligand domain in this process have produced conflicting results. Here, we resolve this conflict by showing that apparently similar C-terminal mutations of the GluR1 PDZ-ligand domain result in opposite physiological phenotypes during activity- and CamKII-induced synaptic plasticity. 相似文献
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There has been growing interest in exploring human performance for situations in which stimuli and/or responses vary along
both horizontal and vertical dimensions. Earlier studies indicated that there is a prevalence of the horizontal dimension
over the vertical dimension in the spatial codes that are used for response selection. We review evidence about spatial coding
for 2-D stimulus—response sets and accounts that have been proposed for explaining how it takes place. Particular attention
is devoted to the relative salience account, which provides the most comprehensive explanation of 2-D spatial coding. We also
evaluate the influence of speed of spatial code formation, number of reference frames, and learning on subjects’ performance
in 2-D tasks. 相似文献
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Prado-Alcalá RA Díaz del Guante MA Garín-Aguilar ME Díaz-Trujillo A Quirarte GL McGaugh JL 《Neurobiology of learning and memory》2006,86(2):144-149
The hypothesis that memory is stored through a single stage of consolidation that results in a stable and lasting long-term memory has been challenged by the proposition that reactivation of a memory induces reconsolidation of the memory. The reconsolidation hypothesis is supported by evidence that, under some conditions, post-retrieval treatments affecting amygdala and hippocampus functioning impair subsequent retention performance. We now report that repeated retention testing attenuates the performance impairment induced by post-retrieval reversible inactivation of the amygdala and hippocampus of rats induced by tetrodotoxin. These findings challenge the reconsolidation hypothesis and suggest that the post-retrieval retention performance impairment is best explained as due to temporary retrieval failure. 相似文献