The phonological-similarity effect differentiates between two working memory tasks

Working memory is a set of interactive cognitive processes that maintain information on–line and available for analysis. Part of the system is specialized for maintaining verbal information, a core component of which is thought to be a phonological store. On the basis of the study of patients with acquired brain lesions, this store has been localized to the supramarginal and angular gyri of the speech–dominant hemisphere, and some functional neuroimaging studies support this localization. However, other imaging studies localize the phonological store in a more dorsal region of the parietal lobe. To reconcile these findings, we examined the phonological–similarity effect in two different tasks. A phonological–similarity effect was observed only in the task that involved sequential presentation and explicit verbal rehearsal. We conclude that at least one possible source of the differences in brain activation between different working memory tasks may be differences in phonological processing.     

High cost helping scenario: The role of empathy,prosocial reasoning and moral disengagement on helping behavior

This study aimed to investigate the process that leads people to offer or omit help in response to an explicit request for assistance, taking into account both emotional and cognitive factors. Specifically, a hypothetical scenario methodology was used in a sample of 174 Italian youths (50% males) to examine whether and how factors such as empathy, prosocial moral reasoning and moral disengagement influence the propensity to help when providing assistance is not in the individual’s personal interest. While a few previous studies have included moral disengagement as an antecedent of prosocial decision making, we highlight the significance of this factor in the avoidance of moral responsibility towards others in need. The results highlight two ways in which differences in emotional tendencies and moral-cognitive processes may operate in prosocial decision making in high personal cost situations. First, high empathy levels could promote an altruistic response which in turn fosters mature prosocial moral reasoning. Second, personal distress may enhance moral disengagement mechanisms that may facilitate self-centred behaviors.     

Cerebellum and processing of negative facial emotions: Cerebellar transcranial DC stimulation specifically enhances the emotional recognition of facial anger and sadness

Some evidence suggests that the cerebellum participates in the complex network processing emotional facial expression. To evaluate the role of the cerebellum in recognising facial expressions we delivered transcranial direct current stimulation (tDCS) over the cerebellum and prefrontal cortex. A facial emotion recognition task was administered to 21 healthy subjects before and after cerebellar tDCS; we also tested subjects with a visual attention task and a visual analogue scale (VAS) for mood. Anodal and cathodal cerebellar tDCS both significantly enhanced sensory processing in response to negative facial expressions (anodal tDCS, p=.0021; cathodal tDCS, p=.018), but left positive emotion and neutral facial expressions unchanged (p>.05). tDCS over the right prefrontal cortex left facial expressions of both negative and positive emotion unchanged. These findings suggest that the cerebellum is specifically involved in processing facial expressions of negative emotion.     

Horizontal Plane Head Stabilization During Locomotor Tasks

Frequency characteristics of head stabilization were examined during locomotor tasks in healthy young adults (N = 8) who performed normal walking and 3 walking tasks designed to produce perturbations primarily in the horizontal plane. In the 3 walking tasks, the arms moved in phase with leg movement, with abnormally large amplitude, and at twice the frequency of leg movement. Head-in-space angular velocity was examined at the predominant frequencies of trunk motion. Head movements in space occurred at low frequencies (< 4.0 Hz) in all conditions and at higher frequencies (> 4.0 Hz) when the arms moved at twice the frequency of the legs. Head stabilization strategies were determined from head-on-trunk with respect to trunk frequency profiles derived from angular velocity data. During natural walking at low frequencies (< 3.0 Hz), head-on-trunk movement was less than trunk movement. At frequencies 3.0 Hz or greater, equal and opposite compensatory movement ensured head stability. When arm swing was altered, compensatory movement guaranteed head stability at all frequencies. Head stabilization was successful for frequencies up to 10.0 Hz during locomotor tasks Maintaining head stability at high frequencies during voluntary tasks suggests that participants used feedforward mechanisms to coordinate head and trunk movements. Maintenance of head stability during dynamic tasks allows optimal conditions for vestibulo-ocular reflex function.     

Selective review,optimism and HIV risk perception

Abstract

Research suggests that review of risk factors increases optimism about health. The present experimental study explored the effects of reviewing risk increasing and risk decreasing factors on HIV risk perception (own risk, others' risk, optimism), self efficacy and behavioural intentions. 164 heterosexual subjects completed a questionnaire concerning their beliefs about HTV and their sexual behaviour. Subjects were allocated to either the risk increasing condition (eg. since being sexually active how often have you asked your partners HIV status?), the risk decreasing condition (eg. since being sexually active how often have you tried to select your sexual partners carefully?), or a control group. The results suggest that review of risk decreasing factors increased optimism and that this change in optimism was related to an increase in perceived others' risk. The results are discussed in terms of theories of selective focus and egocentricism in risk perception and the implications for health promotion.     

Adverse Childhood Experiences and Diabetes in Adulthood: Support for a Collaborative Approach to Primary Care

Prior studies have demonstrated an association between retrospective reports of experiencing trauma in childhood and the current incidence of type 2 diabetes in adulthood. Much less is known about this association among low-income minority patients in primary care settings. We replicated the adverse childhood experiences (ACEs) Centers for disease control and prevention (CDC) study with a low-income minority sample of primary care patients (N = 801) at a community-based healthcare center. We conducted a cross-sectional retrospective quantitative survey study to examine the association between participants’ reports of past childhood trauma and their current health care outcomes. Data were analyzed using binary logistic regression to evaluate the hypothesis that low income minority patients who reported more childhood trauma (abuse, neglect, household dysfunction, cumulative adverse childhood experiences [ACEs]) would more likely be diagnosed with type 2 diabetes. Results suggest that the number of ACEs in our sample were considerably higher than the original CDC ACEs study, as almost 50 % of patients surveyed at our clinic reported 4 or more ACEs, confirming that trauma is central in our urban primary care setting. The results of the cumulative ACEs score was in the expected direction and was significant, suggesting that participants who cumulatively reported experiencing more childhood trauma were more likely to be diagnosed with type 2 diabetes in adulthood. These findings have implications for family therapists, primary care providers, researchers, and policy makers to develop more collaborative approaches to primary care that better target the negative sequelae of ACEs.     

Handedness in a virtual haptic environment: Assessments from kinematic behavior and modeling

This study evaluated hand asymmetries in performance of a dexterous, controlled task under haptic feedback. Participants punctured a virtual membrane with a pushing or pulling movement, using the left or right hand. For pulling movements, the dominant (right) hand exhibited faster average stopping latency and shorter skidding distance. When the kinematic data were fit to a three-phase model previously applied to this task (Klatzky et al., 2013), the right hand exhibited faster force decay attributable to biomechanical factors. Analyses of the aggregated performance measures and model parameters showed that the left and right hands are associated with two different distributions, supporting handedness effects. Furthermore, while the majority of participants expressed right-hand dominance, which was consistent with their self-reported hand preferences, others showed partial or no dominance. This approach could potentially be extended to quantify and differentiate individuals with difficulties in manual behavior due to abnormal motor control (e.g., dyspraxia), progressive deterioration (e.g., Parkinson's syndrome) or improvement (neural regrowth after transplant).     

Attentional control in the attentional blink is modulated by odor

Increasing evidence suggests that `aromas have distinctive effects on the allocation of attention in space: Arousing olfactory fragrances (e.g., peppermint) are supposed to induce a more focused state, and calming olfactory fragrances (e.g., lavender) a broader attentional state. Here, we investigate whether odors have similar effects on the allocation of attention in time. Participants performed the attentional blink (AB) task, known to produce a deficit in reporting the second of two target stimuli presented in close succession in a rapid sequence of distractors, while being exposed to either a peppermint or a lavender aroma. In two experiments using a between-subjects and a within-subjects design, respectively, we show that the two odors have specific effects on attentional control: As compared with the calming lavender aroma, the arousing peppermint condition yielded a larger AB. Our results demonstrate that attentional control is systematically modulated by factors that induce a more or a less distributed state of mind.     

Increasing ethnic minority participation in substance abuse clinical trials: lessons learned in the National Institute on Drug Abuse's Clinical Trials Network

Underrepresentation in clinical trials limits the extent to which ethnic minorities benefit from advances in substance abuse treatment. The objective of this article is to share the knowledge gained within the Clinical Trials Network (CTN) of the National Institute on Drug Abuse and other research on recruiting and retaining ethnic minorities into substance abuse clinical trials. The article includes a discussion of two broad areas for improving inclusion-community involvement and cultural adaptation. CTN case studies are included to illustrate three promising strategies for improving ethnic minority inclusion: respondent-driven sampling, community-based participatory research, and the cultural adaptation of the recruitment and retention procedures. The article concludes with two sections describing a number of methodological concerns in the current research base and our proposed research agenda for improving ethnic minority inclusion that builds on the CTN experience.