From pregnancy to motherhood: The structure of representative and narrative change

The aim of this work was to identify ways of objectifying the course of mothers' represen tations of their babies and themselves as mothers during pregnancy and the postpartum period. A sample of 51 women attending a Family Guidance Clinic for psychoprophylaxis courses was studied using semistruc tured interviews that were administered in the 7th month of pregnancy and on the 5th day and in the 4th month postpartum. This paper describes a method for classifiying themes identified in the mothers' representations of the baby and of the self-as-mother as wish-organized, defense-organized, fear-organized, or disorganized. This classification derives from the presumed clinical function of the narrative themes in the mothers' representational world. Themes about the baby and about the self-as-mother were primarily fear-organized at the 7th month of pregnancy. On the 5th day postpartum, there was no prevailing thematic organization. At 4 months postpartum, representations of the baby were primarily fear-organized and almost never disorganized. We speculate that themes about the baby and the self-as-mother that are disorganized may have negative prognostic significance.     

Regulation and Mechanism of L-Type Calcium Channel Activation via V1a Vasopressin Receptor Activation in Cultured Cortical Neurons

We have sought to elucidate the biochemical mechanisms that underlie the memory enhancing properties of the neural peptide vasopressin. Toward that goal we have investigated vasopressin induction of calcium signaling cascades, long held to be involved in long-term memory function, in neurons derived from the cerebral cortex, a brain region associated with long-term memory. Our previous studies demonstrated that in cultured cortical neurons, V1a vasopressin receptor (V1aR) activation resulted in a sustained rise in intracellular calcium concentration that was dependent on calcium influx (Son & Brinton, 1998). To investigate the mechanism of V1aR-induced calcium influx, we investigated V1aR activation of the calcium channel subtype(s) in cortical neurons cultured from Sprague-Dawley rat embryonic day 18 fetuses. The results of these analyses demonstrated that the L-type calcium channel blocker nifedipine blocked 250 nM V1 vasopressin receptor agonist (V1 agonist)-induced calcium influx. Intracellular calcium imaging analyses using fura-2AM demonstrated that blockade of L-type calcium channels prevented the 250 nM V1 agonist-induced rise in intracellular calcium concentration. These results indicate that the influx of extracellular calcium via L-type calcium channels is an essential step in the initiation of the V1 agonist-induced rise in intracellular calcium concentration. To determine the mechanism of V1aR activation of L-type calcium channels, regulatory components of the phosphatidylinositol signaling pathway were investigated. The results of these analyses demonstrated that V1 agonist-induced calcium influx was blocked by both a phospholipase C inhibitor (U-73122) and a protein kinase C inhibitor (bisindolylmaleimide I). Further analysis of V1aR activation of protein kinase C (PKC) demonstrated that V1 agonist induced PKC activity within 1 min of exposure in cultured cortical neurons. These data indicate that in cultured cortical neurons, V1aR activation regulates the influx of extracellular calcium via L-type calcium channel activation through a protein kinase-C-dependent mechanism. The results of these studies provide biochemical mechanisms by which vasopressin could enhance memory function. Those mechanisms include a complex cascade that is initiated by activation of the phosphatidylinositol pathway, activation of protein kinase C, followed by phosphorylation of L-type calcium channels to initiate the influx of extracellular calcium to activate a cascade of calcium-dependent release of intracellular calcium.     

Breakdowns in flexible use of information: Intelligence-related differences in transfer following equivalent learning performance

Groups of retarded and nonretarded children were investigated as they learned three rules underlying problems adapted from the Raven Progressive Matrices Test: rotation, imposition, and subtration. The interest was in evaluating group differences in the ease with which the original set of rules was learned and the flexibility with which these rules were transferred to modified contexts. In the case of either learning or transfer, the metric of performance was the amount of aid, specifically the number of computer-generated graduated hints, needed for each subject to solve the problems. The groups were matched on their entering competence to deal with the rules under scrutiny, and also on mental age. No group differences were obtained as the subjects learned the original set of rules. However, on subsequent occasions when required to make flexible use of those rules, clear group differences emerged; and those differences increased as the similarity of the training and test contexts decreased. The results were seen as consistent with theories that emphasize transfer flexibility as one potential source of individual and comparative differences in intelligence.     

The internal structure of English transitive sentences

A major question in psychology is whether the same mechanisms are required for language learning and processing as for other cognitive tasks. A substantial body of literature has shown that natural categories are organized around a prototype, with other category members resembling the prototype to a greater or lesser amount based on the degree of shared properties. In order to investigate whether the prototype notion could be extended to linguistic phenomena, adult students (N=148) rated 512 sentences on a 7-point scale as to their goodness of fit to the categoryEnglish transitive sentence. Sentences differed in the animacy fo their actors and patients, the noun pairs used as actor/patient exemplars, and the hypothesized prototypicality of their verbs. Each of the identified factors showed the spread in ranking across different exemplars that is typical of other natural categories, but the factors interacted with each in complex ways to determine the overall ranking of the sentence. Not all sentences were equally representative of the categoryEnglish transitive sentence. In general, sentences with animate actors, high-prototypicality verbs, and animate patients were the most prototypical, followed closely by sentences with animate actors high-prototypicality verbs, and inanimate patients. Results were consistent with the suggestion that language and other types of cognitive tasks require the same basic processes and structures.     

Dynamically oriented group therapy with alcoholics: Making it work despite the prevailing bias

A bias exists in the psychiatric community against dynamically oriented group therapy with alcoholics. The basis for this bias lies primarily in negative experiences of practitioners who have attempted to use traditional therapy with alcoholic patients who continued to drink. At Appleton Outpatient Clinic, we have found that dynamically oriented group therapy is a highly suitable treatment modality for alcoholic patients when negative biases of treators can be addressed and when initial preparatory work is done with patients. This preparatory work includes: (a) building a working alliance around abstinence and providing adequate supports to make this possible; (b) explicit contracting that establishes clear treatment goals and consequences should the goals not be met; (c) preparatory short-termgroup experiences.This paper was presented at the 1988 annual meeting of the American Group Psychotherapy Association.     

Stages of manual exploration in haptic object identification

In a yes/no identification task using touch alone, subjects indicated whether an object belonged to a named category. Previously, we found that subjects explored in two stages—first grasping and lifting the object, then executing further exploratory procedures (Lederman & Klatzky, 1990b). We proposed that Stage 1 (grasp/lift) was sufficient to extract coarse information about multiple object properties, whereas Stage 2 was directed toward precise information about particularly diagnostic properties. the current study, subjects were initially constrained to grasping and lifting, after which they could explore further. Accuracy was above chance after Stage 1, confirming our assumption that the grasp/lift combination was broadly useful. Stage 2 increased accuracy and confidence. It primarily elicited exploratory procedures associated with object geometry, but exploration was also influenced by diagnostic object properties.     

Assessing auditory distance perception using perceptually directed action

Three experiments investigated auditory distance perception under natural listening conditions in a large open field. Targets varied in egocentric distance from 3 to 16 m. By presenting visual targets at these same locations on other trials, we were able to compare visual and auditory distance perception under similar circumstances. In some experimental conditions, observers made verbal reports of target distance. In others, observers viewed or listened to the target and then, without further perceptual information about the target, attempted to face the target, walk directly to it, or walk along a two-segment indirect path to it. The primary results were these. First, the verbal and walking responses were largely concordant, with the walking responses exhibiting less between-observer variability. Second, different motoric responses provided consistent estimates of the perceived target locations and, therefore, of the initially perceived distances. Third, under circumstances for which visual targets were perceived more or less correctly in distance using the more precise walking response, auditory targets were generally perceived with considerable systematic error. In particular, the perceived locations of the auditory targets varied only about half as much in distance as did the physical targets; in addition, there was a tendency to underestimate target distance, except for the closest targets.     

Health Risk Behaviors and Their Relationships to Health Care Utilization Among Veterans Receiving Primary Medical Care

This paper reports the findings of a behavioral health risk screening form and examines the interrelationships among behavioral risk factors and health care utilization. Participants were 1,000 veterans who completed a brief self-report questionnaire assessing affective distress and behavioral health risk factors while they waited to see their primary care provider. Participants reported a mean level of affective distress in the mild range on a scale of 0 to 20 (M = 6.4, SD = 4.95), and 22.4% reported moderate or high levels of affective distress. Fifty percent of the sample denied alcohol use; 5% of the men and none of the women reported a pattern of use that met established criteria for at-risk drinking. Twenty-six percent of the sample reported current tobacco use, 45% acknowledged concerns about diet and/or weight, and 54% reported concern about pain. These factors were largely significantly intercorrelated and several were related to indices of health care utilization. It was concluded that veterans receiving health care in primary care settings report significant levels of affective distress and other health risk behaviors and that the presence of these factors is associated with increased use of the health care system. These data encourage increased efforts to identify these factors and to develop behavior change interventions.     

Labeling effects on memory for nonsense pictures

It has been shown that labeling nonsense pictures improves memory for them, but how the label takes effect is uncertain. In this study subjects viewed nonsense pictures with or without labels; in the former case, the labels were either meaningful or nonmeaningful with respect to the pictures. Then the subjects took part in a free recall test, followed by recall in the presence of cues. Only the meaningful labels facilitated free recall of the pictures, but both types of labels facilitated cued recall. The results suggest that a meaningful label affects picture encoding by providing a conceptual interpretation for the picture; a nonmeaningful label, in contrast, appears to provide only an ad hoc associative cue.