A case of developmental exposure to inorganic mercury

This case report describes behavioral and neuropsychological function in a young man who experienced chronic exposure to elemental mercury at home from age 4 through 9 years. Data are presented on school history, behavior, and performance on standardized tests during the developmental period, and from a full neuropsychological evaluation at age 19 years, several years after environmental exposure had ended. These data specify the course of a decline in function as development proceeds. The patient's progress appeared normal in the preschool period but pronounced academic difficulties and persistent emotional irritability emerged during the elementary school years. At age 19 years, neuropsychological testing revealed diminished executive function, difficulties with language, problems with visuospatial orientation, deficiencies in tine motor control, and manual tremor. Tension, irritability, and depressive affect were evident as well as marked problems with academic performance. These findings suggest widespread cerebral dysfunction, both cortical and subcortical, and are consistent with the diffuse pattern of brain damage seen in children with exposure to heavy metals.     

Expectancy bias mediates the link between social anxiety and memory bias for social evaluation

Social anxiety (SA) involves a multitude of cognitive symptoms related to fear of evaluation, including expectancy and memory biases. We examined whether memory biases are influenced by expectancy biases for social feedback in SA. We hypothesised that, faced with a socially evaluative event, people with higher SA would show a negative expectancy bias for future feedback. Furthermore, we predicted that memory bias for feedback in SA would be mediated by expectancy bias. Ninety-four undergraduate students (55 women, mean age = 19.76 years) underwent a two-visit task that measured expectations about (Visit 1) and memory of (Visit 2) feedback from unknown peers. Results showed that higher levels of SA were associated with negative expectancy bias. An indirect relationship was found between SA and memory bias that was mediated by expectancy bias. The results suggest that expectancy biases are in the causal path from SA to negative memory biases for social evaluation.     

Sex Selection Technology: A Prediction of Its Use and Effect

We surveyed 281 undergraduates to assess their sexual preference for a firstborn child and their willingness to use sex selection technology. Results indicated overall preference for a boy among these respondents whether or not they indicated a willingness to use reproductive technology. Black women reported a greater willingness to use technology than did White women (p < .05), and older respondents (p < .10) also reported a greater intention to use the technology. Catholics were less willing to use technology than all other religious sects (p < .05). Of the 51 respondents who indicated their willingness to use technology, 73% preferred sons (p < .01). This finding held across sex, race, religion, age, and income levels. Support for the women's movement was unrelated to either preference or projected use of sex selection technology.     

Since when or how often? Dissociating the roles of age of acquisition (AoA) and lexical frequency in early visual word processing

The aim of the study was to investigate the effect of both word age of acquisition (AoA) and frequency of occurrence on the timing and topographical distribution of ERP components. The processing of early- versus late-acquired words was compared with that of high-frequency versus low-frequency words. Participants were asked to perform an orthographic task while EEG was recorded from 128 sites. RTs showed an effect of both word AoA and lexical frequency. ERPs revealed a neuro-functional dissociation between AoA and frequency effects in early word processing. AoA modulated the amplitude of left occipito-temporal selection-negativity, suggesting an effect of AoA on early orthographic and lexical access and revealing the crucial role of AoA in determining how words are neurally represented in the ventral pathway. Lexical frequency modulated the amplitude of left anterior negativity, providing evidence for the involvement of the left inferior frontal cortex in the processing of low-frequency words.     

September 11th,an attack at the limits of thought

The paper deals with imagination and its failures from a psychoanalytic perspective. We offer a definition of imagination failures and suggest how they can be interpreted as an opportunity to learn from experience. In order to show that the topic has a concrete and not only speculative significance we consider the public report on September 11 as a case study. The report was published by the National Commission on Terrorist Attacks Upon the United States after a long investigation of the facts and circumstances relating to the September 11 attacks. The document has been the object of strong criticisms, as we argue in the paper. Both the document and some of the critiques that it received focus, however, on significant aspects of the debate about imagination, such us the fragility of imaginative thought, its dependence on unconscious desires and its plurality of outcomes: a plethora of imaginaries can in fact be developed at any time, from the same set of information about reality. We comment on these aspects and reinterpret them from a Bionian perspective. The concepts of ‘unthinkability’, ‘imagination failure’ and ‘depressive position’ are used to inform the necessity of dealing with an evolving and conflictual geopolitical scenario. Particular attention is paid to the proposal of ‘routinizing, even bureaucratizing, the exercise of imagination’ within the institutions that deal with National Defense. This possibility is discussed in depth in order to suggest how it may be concretely implemented. In conclusion, a strong case is made for the usefulness of psychoanalytic reflection in the arena of relationships among countries, with particular emphasis on the new terrorist challenges.     

Effect of Transcranial Direct Current Stimulation Combined With Virtual Reality Training on Balance in Children With Cerebral Palsy: A Randomized,Controlled, Double-Blind,Clinical Trial

The authors' aim was to investigate the effects of continuous transcranial direct current stimulation (tDCS) combined with virtual reality training on static and functional balance in children with cerebral palsy (CP). Twenty children with CP (6 girls and 14 boys; M age = 7 years 6 months ± 2 years) were randomly allocated to two groups. The experimental group received active tDCS and the control group received sham stimulation during the 10 sessions of virtual reality mobility training protocols. The children were evaluated on 3 occasions (preintervention, postintervention, and 1-month follow-up). Static balance was evaluated using a force plate under 4 conditions: feet on force plate with (a) eyes open and (b) with eyes closed, and feet on foam mat with (c) eyes open and (d) with eyes closed. Functional balance was evaluated using the Pediatric Balance Scale and the Timed Up and Go Test. The analyses demonstrated statistically significant postintervention and follow-up effects favoring the experimental group over the control group with regard to the Pediatric Balance Scale, Timed Up and Go Test, and area of oscillation of the center of pressure when standing on the force plate with eyes open. The present findings suggest that tDCS can potentiate the effects of virtual reality training on static and functional balance among children with CP.