The crane's foot: The rise of the pedigree in human genetics

The standard pedigree used by geneticists is intimately connected to the history of genetics. Pedigrees drawn today are based on standards established in the early decades of the twentieth century. Those standards were established by geneticists who pursued an active interest in eugenics. The slightly different standards followed in America vs. England to some extent followed the stronger support of Mendelism by the Americans, as well as the individual preferences of the leading human geneticists in those countries.     

Nonsuicidal physically self-damaging acts in adolescents

To determine the frequency and correlates of nonsuicidal physically self-damaging acts in 12–14 year olds, a two stage epidemiologic survey with a self-administered questionnaire (N=3283) followed by a psychiatric interview of a subsample of the adolescents and their parents (N=444) was used. Prevalence estimates of interview validated nonsuicidal physically self-damaging acts were 2.46% in males and 2.79% in females. Significant relationships were found between nonsuicidal physically self-damaging acts and suicidal ideation, major depression and undesirable life events. Data suggest that physically self-damaging acts occur at substantial rates during early adolescence. The strong correlation between nonsuicidal self-destructive acts and both suicidal ideation and major depression clarifies prior conflicting reports in the literature and suggests that a history of self-damaging acts should be taken into consideration when evaluating for possible depression and suicide risk.     

Drawing the boundary between subject and object: Comments on the mind-brain problem

Physics says that it cannot deal with the mind-brain problem, because it does not deal in subjectivities, and mind is subjective. However, biologists (among others) still claim to seek a material basis for subjective mental processes, which would thereby render them objective. Something is clearly wrong here. I claim that what is wrong is the adoption of too narrow a view of what constitutes ‘objectivity’, especially in identifying it with what a ‘machine’ can do. I approach the problem in the light of two cognate circumstances: (a) the ‘measurement problem’ in quantum physics, and (b) the objectivity of standard mathematics, even though most of it is beyond the reach of ‘machines’. I argue that the only resolution to such problems is in the recognition that closed loops of causation are ‘objective’; i.e. legitimate objects of scientific scrutiny. These are explicitly forbidden in any machine or mechanism. A material system which contains such loops is called ‘complex’. Such complex systems thus must possess nonsimulable models; i.e. models which contain impredicativities or ‘self-references’ which cannot be removed, or faithfully mapped into a single coherent syntactic time-frame. I consider a few of the consequences of the above, in the context of thus redrawing the boundary between subject and object.     

The semantics ofR4

The LogicR4 is obtained by adding the axiom (A vB(AvB) to the modal relevant logicNR. We produce a model theory for this logic and show completeness. We also show that there is a natural embedding of a Kripke model forS4 in eachR4 model structure.We are indebted to several people for discussions relating to the topic of this paper, in particular, Kit Fine, John Slaney, J. M. Dunn, Jacques Riche, M. A. McRobbie, and Jill LeBlanc. We would also like to thank the Automated Reasoning Project for material assistance. Mares would like to thank The Social Sciences and Humanities Research Council of Canada for fellowships 456-89-0128 and 457-90-0081, which supported him while writing this paper.     

Genetic and Environmental Effects on Openness to Experience, Agreeableness, and Conscientiousness: An Adoption/Twin Study

ABSTRACT Previous research has indicated that extraversion and neuroticism are substantially affected both by genotype and environment. This study assesses genetic and environmental influences on the other three components of the five-factor model of personality: Openness to Experience, Agreeableness, and Conscientiousness. An abbreviated version of the NEO Personality Inventory (NEO-PI) was administered to 82 pairs of identical twins and 171 pairs of fraternal twins reared apart and 132 pairs of identical twins and 167 pairs of fraternal twins reared together. Estimates of genetic and environmental effects for Openness and Conscientiousness were similar to those found in other studies of personality: Genetic influence was substantial and there was little evidence of shared rearing environment. Results for Agreeableness were different: Genetic influence accounted for only 12% of the variance and shared rearing environment accounted for 21% of the variance. Few significant gender or age differences for genetic and environmental parameters were found in model-fitting analyses.     

Interviewers’ Moods and Evaluations of Job Applicants: The Role of Applicant Qualifications1

Participants were induced to experience positive affect, negative affect, or no shift in current affect. Then they conducted a simulated job interview with an applicant (actually an assistant) who appeared to be highly qualified, ambiguously qualified, or unqualified for the job in question. It was predicted that interviewers’ moods would exert the strongest influence on ratings of the applicant when this person's qualifications were ambiguous. Results offered partial support for this hypothesis. When the applicant's qualifications were ambiguous, participants induced to experience positive affect rated this person higher on several dimensions than participants induced to experience negative affect. When the applicant appeared to be highly qualified for the job, in contrast, interviewers’ moods had no significant effect on their ratings of this person. Contrary to expectations, however, interviewers’ moods significantly influenced ratings of the applicant when this person appeared to be unqualified for the job in question. In this condition, participants induced to experience positive affect actually rated the applicant lower than those induced to experience negative affect. Several mechanisms that may have contributed to these results (e. g., tendencies toward mood maintenance, adoption of a positive-test strategy) are examined. In addition, practical implications of these findings for conducting job interviews and for the use of various impression-management techniques by applicants are discussed.