Glucose and physostigmine effects on morphine- and amphetamine-induced increases in locomotor activity in mice

Recent findings indicate that glucose antagonizes several behavioral effects of cholinergic antagonists and augments those of cholinergic agonists. For example, scopolamine elicits increased locomotor activity, an action which is attenuated by glucose and by combined treatment with glucose and physostigmine at doses which are individually without effect. Opiate and catecholamine agonists, such as morphine and amphetamine, also elicit hyperactivity. The present study examined interactions of glucose and physostigmine with morphine- and amphetamine-induced hyperactivity. Mice received saline, morphine (10 mg/kg), or amphetamine (1 mg/kg) 50 min prior to testing, followed by saline, physostigmine (0.01, 0.05, 0.1, or 0.2 mg/kg), or glucose (10, 50, 100, or 500 mg/kg) administered 20 min prior to activity testing in an open field. Physostigmine significantly attenuated both morphine- and amphetamine-induced increases in activity, but higher doses were required to attenuate the effects of amphetamine. Like physostigmine, glucose significantly attenuated morphine-induced activity levels, but unlike physostigmine, glucose did not attenuate amphetamine-induced activity. Thus, the behavioral effects of morphine were more susceptible to modification by physostigmine and glucose than were the effects of amphetamine. The attenuation of morphine-induced hyperactivity demonstrates a similarity between glucose and cholinergic agonists, and also indicates that glucose may inhibit, directly or indirectly, opiate functions. More generally, these findings add to the evidence that circulating glucose levels selectively influence a growing list of behavioral and neurobiological functions.     

What is the pronunciation for -ough and the spelling for /u/? A database for computing feedforward and feedback consistency in English

Recent studies suggest that performance attendant on visual word perception is affected not only by feedforward inconsistency (i.e., multiple ways to pronounce a spelling) but also by feedback inconsistency (i.e., multiple ways to spell a pronunciation). In the present study, we provide a statistical analysis of these types of inconsistency for all monosyllabic English words. This database can be used as a tool for controlling, selecting, and constructing stimulus materials for psycholinguistic and neuropsychological research. Such large-scale statistical analyses are necessary devices for developing metrics of inconsistency, for generating hypotheses for psycholinguistic experiments, and for building models of word perception, speech perception, and spelling.     

Perceived fairness of biodata as a function of the purpose of the request for information and gender of the applicant

Using a 2×2 experimental design and data from 86 business students, the present study examined the main and interactive effects of the purpose of the request (personnel selection vs. career tracking), and applicant gender (male vs. female) on the perceived fairness of biodata. Results revealed a significant main effect for purpose and a purpose x gender interaction. Implications for the collection of biodata in the personnel selection process are discussed.     

BERNARD MELAND ON THE NEW FORMATIVE IMAGERY OF OUR TIME

Abstract. One of the key influences on radical empiricist theology, the thought of Bernard Meland is a challenge to overemphasis on precision and rigor of proof. This article (1) provides an introduction to Meland, (2) summarizes his view of the significance of post-Newtonian physics and of Darwin for religion, (3) discusses his relationship to Henry Nelson Wieman, and (4) assesses his contribution to current discussion in science and theology.     

The listening heart and the chi square: clinical and empirical perceptions in the family therapy of anorexia nervosa

Clinical and empirical methods are commonly considered to be complementary activities. However, many people in the fields of mental health and social welfare espouse a strong adherence to experimental, scientific methods for the evolution of theory and practice and consider only that which has been experimentally tested as‘really true”. Others would propose the clinical method as the main source of useful knowledge and are suspicious of enumeration and quantification as sources of useful information. Formal, empirical methodology is well and extensively described whilst there is less systematic exposition of the clinical method. Family therapy evolved in a context in which activity was visible and the emerging discipline was propelled by a theoretical framework with strongly scientific origins that was critical of the exclusive clinical method of pre-existing psychotherapies. This paper describes some of the clinically based contributions to the family therapy of anorexia nervosa and compares this information with that which comes out of the Maudsley trials of psychotherapies in anorexia nervosa.     

Traditional vs. nontraditional women and men's perceptions of the personalities and physiques of ideal women and men

Traditional and nontraditional women and men's perceptions of ideal people, in terms of both traits and physiques, were assessed using 80 male and 80 female Caucasian undergraduates as study participants. The data indicated that traditional women and men perceived the ideal male as mesomorphic and as having more instrumental than expressive traits. Nontraditional women and men also favored a mesomorphic physique for the ideal male, but they differed from traditionals in that they saw this mesomorphic male as being androgynous in regard to traits. Concerning the ideal female, traditional and nontraditional women and men preferred an androgynous physique, but they differed in their perceptions of the ideal personality for a woman. Traditional women and men perceived their ideal women as having more expressive than instrumental traits, whereas nontraditional women and men saw their ideal women as being androgynous in regard to traits. The results are discussed within the framework of Bem's gender schema and enculturated lens theories.     

Direct comparisons between residential and community students on school performance measures in a public school setting

The purpose of the current study was to evaluate the school performance of residential youth who attended a public school setting. Direct comparisons were made between the residential youth and students in the community on a number of school measures. Results from a multivariate analysis of covariance indicated that the residential students had significantly lower grades, participated in significantly fewer extracurricular activities, and exhibited more problematic behaviors such as tardies and absences. These findings were consistent with previous research which found that many residential youth have a number of behavioral, social, and academic difficulties that interfere with school functioning. A number of recommendations were made regarding educational placement for residential youth.     

Brain dynamics,psychophysiological uncertainty and behavioral learning

The present paper takes a first step toward the integration of recent findings on brain dynamics and learning into established fields of psychophysiological science. Leading-edge studies of brain dynamics have shown that the brain manifests an inherent variability and that, when new stimuli (i.e., “problems”) are presented to the organism, brain chaos increases.     

A Social Dilemma Analysis of Commuting Preferences: The Roles of Social Value Orientation and Trust1

The current research advances a social dilemma analysis of commuting, examining the roles of preexisting personality differences in social value orientation (i.e., prosocial vs. proself orientation) and trust (i.e., a general belief in the honesty and cooperative intentions of others) in determining preferences for collectively desirable commuting options: preferences for commuting by public transportation (Study 1) and carpooling (Study 2). Consistent with predictions, both studies revealed that, relative to p of prosocials, preferences of proselfs were more strongly associated with beliefs about the relative efficiency of cars (i.e., an outcome affecting personal well-being). Also, greater preferences for collectively desirable actions were observed among prosocials with high trust—relative to prosocials with low trust and proselfs with high or low trust—providing support for the claim that 2 conditions (i.e., prosocial goals and trust in others) must be met to obtain collectively desirable commuting preferences.