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341.
Affective events theory suggests that affective events at work arouse emotional reactions that influence employees’ attitudes and behaviour in the workplace. In the present study, we apply this theoretical framework to clarify the interplay of variables that explain well-being and performance. We analysed the mediating role of positive affect and work engagement between daily uplifts and well-being, and between daily uplifts and performance. Results from a sample of 293 employees revealed that daily uplifts were positively associated with well-being and performance. While the effects of daily uplifts on well-being were fully mediated by positive affect and work engagement, the effects of daily uplifts on performance were only partially mediated by positive affect and work engagement. In both cases, the effect of positive affect was bigger than that of work engagement. The relations explored provide new theoretical elements for models that explain which variables influence well-being and performance in organizational contexts. The implications for employee health and organizational success are discussed. 相似文献
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343.
Language development in children at risk for language impairment: cross-population comparisons 总被引:2,自引:0,他引:2
At 3 years of age the spontaneous language of 17 typically developing children was compared to two groups of toddlers who were at risk for language delay for very different reasons. One at-risk group, late talkers, appeared normal in all respects except for their delayed language. These 20 children scored at or below the fifteenth percentile for expressive vocabulary on the MacArthur Communicative Development Inventory (Fenson et al., 1993) when originally identified at 20-27 months of age and within the normal range on the Bayley Scales of Infant Development (Bayley, 1969). The other group, 21 children with unilateral focal brain injury, suffered localized damage to their brain prenatally, perinatally, or within the first 6 months of life. Results indicated that both of the at-risk groups were still significantly lower in vocabulary diversity and grammar at 3 years of age. There was also significantly greater variability in the at-risk groups than in the control groups, and in the children with focal brain injury than in the late talkers in both areas. The importance of language comprehension to development in this period was supported by two findings. First, children with focal brain injury had significantly lower scores than late talkers on the Index of Productive Syntax, a test of emerging grammar, and had been lower in comprehension on a standardized test of language comprehension a year earlier. Second, late talkers with delay in comprehension as well as production had significantly lower scores on IPSyn than those with normal comprehension, suggesting that they are at greater risk for continued delay. Qualitative analyses indicated that the at-risk groups produced the same kinds of errors, but that late talkers produced a substantially greater proportion of errors in obligatory contexts than did children with focal brain injury. 相似文献
344.
Conrad CD MacMillan DD Tsekhanov S Wright RL Baran SE Fuchs RA 《Neurobiology of learning and memory》2004,81(3):185-199
Glucocorticoid receptor activation within the basolateral amygdala (BLA) during fear conditioning may mediate enhancement in rats chronically exposed to stress levels of corticosterone. Male Sprague-Dawley rats received corticosterone (400 microg/ml) in their drinking water (days 1-21), a manipulation that was previously shown to cause hippocampal CA3 dendritic retraction. Subsequently, rats were adapted to the fear conditioning chamber (day 22), then trained (day 23), and tested for conditioned fear to context and tone (day 25). Training consisted of two tone (20s) and footshock (500 ms, 0.25 mA) pairings. In Experiment 1, muscimol (4.4 nmol/0.5 microl/side), a GABAergic agonist, was microinfused to temporarily inactivate the BLA during training. Rats given chronic corticosterone showed enhanced freezing to context, but not tone, compared to vehicle-supplemented rats. Moreover, BLA inactivation impaired contextual and tone conditioning, regardless of corticosterone treatment. In Experiment 2, RU486 (0, 0.3, and 3.0 ng/0.2 microl/side) was infused on training day to antagonize glucocorticoid receptors in the BLA. Corticosterone treatment enhanced fear conditioning to context and tone when analyzed together, but not separately. Moreover, RU486 (3.0 ng/side) selectively exacerbated freezing to context in chronic corticosterone-exposed rats only, but failed to alter tone conditioning. Serum corticosterone levels were negatively correlated with contextual, not tone, conditioning. Altogether, these suggest that chronic corticosterone influences fear conditioning differently than chronic stress as shown previously. Moreover, chronic exposure to corticosteroids alters BLA functioning in a non-linear fashion and that contextual conditioning is influenced more than tone conditioning by chronic corticosterone and BLA glucocorticoid receptor stimulation. 相似文献
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347.
Medvedev A Igosheva N Crumeyrolle-Arias M Glover V 《Stress (Amsterdam, Netherlands)》2005,8(3):175-183
(Indoledione 2,3) isatin is an endogenous indole found both in mammalian brain and peripheral tissues. Isatin concentration in blood can exceed 1 microM and tissue concentrations vary from < 0.1 to 10 microM. Its level in the brain and periphery is increased by stress. Isatin has a wide spectrum of behavioural and metabolic effects. It is anxiogenic at lower doses and sedative at higher doses. Its most potent known in vitro actions are as an antagonist of atrial natriuretic peptide (ANP) function and NO signaling. In this review, we discuss isatin and stress in animal models, the few human studies, and also what it is known to date about the molecular mechanisms of its action. We suggest the possibility that isatin and its analogues may be interesting new pharmacological agents; Isatin antagonists may be anxiolytic, and isatin agonists may activate the HPA axis. 相似文献
348.
An unselected sample of adolescents (n= 504) was given a test measuring their social strategies in affiliative context, and emotional and behavioral problems. Four groups of adolescents were identified according to the certain patterns of the social strategies they deployed: Active optimistic group (n= 107), Defensive functional group (n= 159), Avoiders group (n= 89), and Learned helplessness group (n= 140). The degree of stability of a cluster solution was studied when the method for cluster analysis was changed, showing that the four-cluster solution captures the essential relationships between the variables. The membership of the strategy groups was associated in theoretically meaningful ways to the anxiety/depression, withdrawal, and social problems. 相似文献
349.
Aphasic patients with reading impairments frequently substitute incorrect real words for target words when reading aloud. Many of these word substitutions have substantial orthographic overlap with their targets and are classified as "visual errors" (i.e., sharing 50% of targets' letters in the same relative position). Fifteen chronic aphasic patients read a battery of words and non-words; non-word reading was poor for all patients, and more than 50% of errors on words involved the substitution of a non-target word. An investigation of the factors conditioning these word substitutions, as well as the production of visual errors, identified a number of similarities to patterns previously reported for patients with right neglect dyslexia, which has been said to occur relatively rarely. These included a strong tendency for errors to overlap targets in initial letter positions, maintenance of target length in errors, and the substitution of words higher in imageability than targets. It is proposed that left hemisphere damage frequently leads to disruption of a level of representation for written words in which letter position is ordinally coded, resulting in exacerbation of a normal processing advantage for early letter positions. A computational model is discussed that incorporates this level of representation and successfully simulates relevant normal and patient data. 相似文献
350.
Moretti R Torre P Antonello RM Capus L Gioulis M Marsala SZ Cazzato G Bava A 《Perceptual and motor skills》2002,95(2):477-486
The limits of a drug therapy in severe forms of Parkinson disease have led to refining neurosurgery on the basal ganglia. Deep brain stimulation of the subthalamic nucleus has been recognized as one of the most promising techniques to decrease "off" motor symptoms and motor fluctuations, allowing a reduction of drug therapy and limiting side effects of the drugs. There is still open debate on the possible consequences of chronic subthalamic stimulation in other ways, apart from motor symptoms, of general cognitive performance. We examined and followed two patients with Parkinson disease for 9 mo. after surgery for deep stimulation, studying their cognitive performances. There is a general amelioration of cognitive performances, in particular as far as linguistic capabilities is concerned. We discuss the possible significance of these results, reminding strenuously that only two patients were involved, so the potential for generalization is seriously limited. 相似文献