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51.
In this paper are explored the ethical implications of the answers to three questions: Whether or not a diseased state is discrete; the criteria by which that question is answered; and how the diseased state is to be identified. Examples are given showing that some states appear to be clearly discrete, and others equally clearly not discrete. The nature of the pertinent evidence will be affected accordingly. It is shown that a slavish and inappropriate concern with categories leads to anomalous ethics. Finally, it is suggested that many of these problems may be avoided by centering the ethics of medicine on optimizing the welfare of the patient rather than by thinking in terms of categorical disease.  相似文献   
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We investigated the effects of background anger, provocation, and methylphenidate on emotional, physiological, and behavioral responding in children with attentiondeficit hyperactivity disorder (ADHD) with and without concurrent aggression. Our study revealed that ADHD boys showed more emotional and physiological distress when exposed to an interaction in which an administrator chastised each boy's favorite counselor, compared to a friendly interaction between the two adults. The background anger manipulation did not affect the aggressive behavior of the boys against an opponent in an aggressive game. High-aggressive (HA) ADHD boys were more likely to respond to provocation with aggression than low-aggressive (LA) ADHD boys, but only LA boys showed increased physiological reactivity with increasing provocation. Methylphenidate resulted in increased heart rates under all conditions and did not interact with any of the other findings.This project was conducted while the first author had the support of National Institute of Alcohol Abuse and Alcoholism grant AA 06267.The authors wish to thank the staff members of the 1987 Summer Day Treatment Program who assisted in conducting this project. The authors also express their appreciation to Karen Guthrie for coordinating the medication assessment and to Hart Blanton for computer programming.  相似文献   
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Recruiting help from mentors and other potential helpers is a promising strategy for helping disadvantaged and minority youths meet their personal and educational goals. Three African-American high school seniors participated in a project designed to evaluate the effectiveness of training procedures that would allow them to ask for help in attaining educational and other personal goals. A behavioral training procedure that included instructional materials, role-play practice, praise, and feedback was used. Targeted skills included goal setting and 30 responses involved in the process of meeting with a potential helper. Role-play situations were used to evaluate participants' help-recruiting skills before and after training. Participants increased their help-recruiting skills from an average of 38% during baseline, to an average of 75% after training. Self-reported measures of goal attainment suggested that the students benefited from the training. Implications for mentoring programs designed to increase minority students' opportunities to reach educational goals were discussed.  相似文献   
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A within-subject comparison was made of the effects of methylphenidate (Ritalin) and response cost in reducing the off-task behavior of two boys, 7 and 8 years of age, who had been diagnosed as having an attentional deficit disorder with hyperactivity. Several dosages of Ritalin (5 to 20 mg/day) were evaluated with the results indicating varying effects of the drug for both children. Response cost (with free-time as the reinforcer) was superior to Ritalin in raising levels of on-task behavior and in improving academic performance.  相似文献   
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The ‘skewness’ of a distribution, a poorly-defined term, is conventionally deemed to be invariant under linear transformations. A comparison is made of three criteria of it: the sign of odd central moments; the several relationships of the mean, the median and the mode; and asymmetry proper which is the set of ratios of the probability densities of all pairs of points equidistant above and below some arbitrary point, usually the principal mode. Some useful general relationships are discussed. The skeness of convolutions is briefly discussed. A class of distributions is identified for which the skewness of the minimum ofk competing processes is independent ofk. It has importance in the parametric study of survivorship.  相似文献   
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