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141.
Philosophical Studies - This paper focuses on value as ascribed to what can be desired, enjoyed, cherished, admired, loved, and so on: value that putatively serves as ground for evaluating such... 相似文献
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Recent studies point to a major role for alpha2-containing GABA-A receptors in modulating anxiety. However, the possible implication of GABA-A receptors containing the alpha3 subunit on anxiety is less known. The aim of this study was to examine the effects of SB-205384 (0.5-4 mg/kg, i.p.), an alpha3 subunit positive modulator of GABA-A receptor, on anxiety tested in the elevated plus-maze in male mice, using classical and ethological parameters. Mice treated with SB-205384 showed an increase in the frequency of entries and the time spent in open arms, as well as a reduction in the time spent in closed arms, as compared with the control group. A notable increase of "head-dipping" unprotected and a reduction of "stretched-attend posture" protected was also evident. These findings indicate that SB-205384 exhibits an anxiolytic-like profile in the elevated plus-maze test, suggesting that GABA-A receptors which contain the alpha3 subunit might be involved in regulation of anxiety. 相似文献
148.
The aim of the present work is to evaluate the efficacy of a program entitled "Prevention of child sexual abuse" the first structured program in Spain designed to prevent such risks. With this purpose, we carried out a study of 382 minors with ages ranging between 8 and 12 years. The result s show that the program has a very positive impact, increasing the awareness of the minors about this type of risk and improving their skills for coping with a possible event of sexual abuse. The efficacy of the program is also apparent, at the level of secondary prevention, in that it increased the likelihood that the children would reveal such events. Finally, exploration of the possible adverse effects of the program showed that the negative effects observed by parents and educators are negligible. 相似文献
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Hartsuiker RJ Antón-Méndez I Roelstraete B Costa A 《Journal of experimental psychology. Learning, memory, and cognition》2006,32(4):949-953
Lexical bias is the tendency for phonological errors to form existing words at a rate above chance. This effect has been observed in experiments and corpus analyses in Germanic languages, but S. del Viso, J. M. Igoa, and J. E. García-Albea (1991) found no effect in a Spanish corpus study. Because lexical bias plays an important role in the debate on interactivity in language production, the authors reconsidered its absence in Spanish. A corpus analysis, which considered relatively many errors and which used a method of estimating chance rate that is relatively independent of total error number, and a speech-error elicitation experiment provided converging evidence for lexical bias in Spanish. The authors conclude that the processing mechanisms underlying this effect hold cross-linguistically. 相似文献
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Antonio Caselles Joan C. Micó Salvador Amigó 《The British journal of mathematical and statistical psychology》2010,63(2):449-480
The existence of a close relation between personality and drug consumption is recognized, but the corresponding causal connection is not well known. Neither is it well known whether personality exercises an influence predominantly at the beginning and development of addiction, nor whether drug consumption produces changes in personality. This paper presents a dynamic mathematical model of personality and addiction based on the unique personality trait theory (UPTT) and the general modelling methodology. This model attempts to integrate personality, the acute effect of drugs, and addiction. The UPTT states the existence of a unique trait of personality called extraversion, understood as a dimension that ranges from impulsive behaviour and sensation‐seeking (extravert pole) to fearful and anxious behaviour (introvert pole). As a consequence of drug consumption, the model provides the main patterns of extraversion dynamics through a system of five coupled differential equations. It combines genetic extraversion, as a steady state, and dynamic extraversion in a unique variable measured on the hedonic scale. The dynamics of this variable describes the effects of stimulant drugs on a short‐term time scale (typical of the acute effect); while its mean time value describes the effects of stimulant drugs on a long‐term time scale (typical of the addiction effect). This understanding may help to develop programmes of prevention and intervention in drug misuse. 相似文献