Reducing attention‐maintained behavior through the use of positive punishment,differential reinforcement of low rates,and response marking

A differential reinforcement of low (DRL) rates procedure was implemented as a changing criterion design with positive punishment and response marking to reduce attention‐maintained behavior of screaming, profanity, and disruptive behaviors of three adolescent males. One participant was diagnosed with static encephalopathy and attention deficit hyperactivity disorder (ADHD) and severe mental retardation, the other two were diagnosed with Down syndrome, one with moderate mental retardation, and the other with severe mental retardation. Through response marking, a verbal warning was delivered immediately following the initial occurrence of a target behavior. A special token (positive punishment) was immediately delivered with a verbal cue and placed on a behavior board following the next occurrence of that behavior. Appropriate requests (hand‐raising) for attention was acknowledged and reinforced with verbal praise. The DRL procedure, combined with positive punishment and response marking, was successful in decreasing the frequency of targeted behaviors amongst all participants. Copyright © 2009 John Wiley & Sons, Ltd.     

Acute systemic fibroblast growth factor-2 enhances long-term memory in developing rats

Recent findings have provided much insight into the mechanisms underlying long-term memory formation, and it is now known that long-term memory depends on the activation of a molecular cascade that culminates with structural changes in the brain. However, little is known about the signals that give rise to or regulate these structural changes. In this article we propose that fibroblast growth factor-2 (FGF2), a mitogen for several cell types, may be one of the molecular signals critically involved in the structural changes underlying long-term memory. If FGF2 is part of the signalling cascade involved in long-term memory, then increasing the activation of FGF2 should facilitate memory. In Experiments 1 and 2, we demonstrated that systemic injection of FGF2 (20 ng/g of body weight) facilitated memory for contextual fear in 16, 19, and 22 day old male Sprague Dawley rats. Experiment 3 demonstrated that the observed facilitation of memory was not due to FGF2 increasing rats’ sensitivity to footshock. These results implicate FGF2 as a possible molecular signal in long-term memory, and further, illustrate a novel means of enhancing memory.     

Skill theory v2.0: dispositions,emulation, and spatial perception

An attempt is made to defend a general approach to the spatial content of perception, an approach according to which perception is imbued with spatial content in virtue of certain kinds of connections between perceiving organism’s sensory input and its behavioral output. The most important aspect of the defense involves clearly distinguishing two kinds of perceptuo-behavioral skills—the formation of dispositions, and a capacity for emulation. The former, the formation of dispositions, is argued to by the central pivot of spatial content. I provide a neural information processing interpretation of what these dispositions amount to, and describe how dispositions, so understood, are an obvious implementation of Gareth Evans’ proposal on the topic. Furthermore, I describe what sorts of contribution are made by emulation mechanisms, and I also describe exactly how the emulation framework differs from similar but distinct notions with which it is often unhelpfully confused, such as sensorimotor contingencies and forward models.     

Graded motor responses in the time course of categorizing atypical exemplars

The time course of categorization was investigated in four experiments, which revealed graded competitive effects in a categorization task. Participants clicked one of two categories (e.g., mammal or fish) in response to atypical or typical exemplars (e.g., whale or cat) in the form of words (Experiments 1 and 2) or pictures (Experiments 3 and 4). Streaming x, y coordinates of mouse movement trajectories were recorded. Normalized mean trajectories revealed a graded competitive process: Atypical exemplars produced trajectories with greater curvature toward the competing category than did typical exemplars. The experiments contribute to recent examination of the time course of categorization and carry implications for theories of representation in cognitive science.     

Does self-efficacy moderate intensity of pain?

75 subjects were randomly assigned to five self-efficacy conditions (High-High, High-Low, Low-High, Low-Low, and Control) in a 5 x 3 (condition x trial) design. Pressure was applied three times to an exposed finger. After baseline, subjects received false biofeedback (i.e., independent of ratings of pain) that their ability to regulate intensity of pain was either good (High-High and High-Low) or poor (Low-High and Low-Low), or there was no biofeedback (Control). After a second trial, subjects were told that their biofeedback indicated either good (High-High and Low-High) or poor (High-Low and Low-Low) regulatory ability, or they were not given biofeedback (Control). They then received a final trial. Before each trial, subjects recorded self-efficacy expectations for regulating intensity of pain. Mixed multivariate analyses of variance on ratings of intensity and self-efficacy expectations did not yield hypothesized interactions for condition x trial.     

Use of a virtual reality car-driving stressor in cardiovascular reactivity research

Eighteen subjects (11 males, 7 females) completed a virtual reality car-driving stressor on two occasions several weeks apart. Immediately before and throughout task performance, blood pressure, cardiac output, and total peripheral resistance were assessed. Reactivity scores were calculated for each parameter for each subject as the arithmetic difference between task level and baseline level. The task elicited considerable hemodynamic activation on each occasion of testing, as well as high levels of self-reported task realism, engagement, excitement, and nervousness. Correlation analyses of both absolute and reactivity scores revealed evidence of test-retest reliability. Males were found to exhibit greater absolute levels of and greater increases in systolic blood pressure. The development of tasks suitable for inclusion in a battery of behavioral stressors, responses to which may help identify those at risk for later disease, is of considerable interest in cardiovascular behavioral medicine. The present findings suggest that the virtual reality car-driving task may be useful in this context.     

A meta-analysis of bibliotherapy studies

Used meta-analysis to examine the efficacy of bibliotherapy. Bibliotherapy treatments were compared to control groups and therapist-administered treatments. The mean estimated effect size (d) of the 70 samples analyzed was +0.565. There was no significant differences between the effects of bibliotherapy and therapist-administered treatments, as well as no significant erosion of effect sizes at follow-up. Bibliotherapy did appear more effective for certain problem types (assertion training, anxiety, and sexual dysfunction) than for others (weight loss, impulse control, and studying problems). Overall, the amount of therapist contact during bibliotherapy did not seem to relate to effectiveness, but there was evidence that certain problem types (weight loss and anxiety reduction) responded better with increased therapist contact. Recommendations for future research were given, especially for more research on the commonly purchased books and moderator analyses by personality type and reading ability. This article is based on a doctoral dissertation by Rick W. Marrs under the direction of Steven D. Brown at Loyola University of Chicago. I gratefully acknowledge the assistance of Dr. Brown as well as of my other committee members, Joseph Durlak and Gloria Lewis. I also gratefully acknowledge the assistance in coding done by Laura Marrs and John Gibson and helpful editorial comments made by Wayne Lucht.     

Endogenous Ketamine-Like Compounds and the NDE: If So, So What?

This commentary on Karl Jansen's ketamine model for the near-death experience expands upon and raises additional questions about several issues and hypotheses: self-experimentation as a source of data; ketamine's similarities to and differences from classical hallucinogens; the need for quantification of unusual subjective states; clinical research and toxicological implications of this model; drugs as gateways to religious states; and evolutionary versus religious significance of naturally occurring compounds released in the near-death state. I suggest future research that could help explicate several of these areas.Formerly Associate Professor of Psychiatry at the University of New Mexico School of Medicine     

LISTENING TO NICOTINE:

Abstract— In recent years, theoretical models of drug motivation and drug dependence have downplayed the role of withdrawal symptoms in the maintenance of addiction. During this same period, strong links between drug use and measures of negative affect have been uncovered in empirical research. In this article we examine these trends in the context of research on smoking. Evidence is presented from two recent studies on smoking relapse that highlight the intimate connection between withdrawal symptomatology and negative affect Specifically, these studies reveal that (a) single-occasion measures of withdrawal symptoms or other markers of physical dependence do not contribute incremental validity in preceding relapse relative to measures of negative affect (b) the trajectory of withdrawal symptoms is highly idiosyncratic, (c) exacerbations cannot be tightly coupled with pharmacological events. (d) the temporal dynamics of withdrawal reflect fluctuations in negative affect, and (e) differences in the trajectory of withdrawal symptoms index relapse vulnerability. We conclude that a broadened view of withdrawal recognizing its probable affective bases will enhance its explanatory power and suggest new treatment strategies.