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71.
These experiments examined the effects of the NMDA-receptor (NMDAr) antagonist MK801 on reacquisition and re-extinction of a conditioned fear that had been previously extinguished before injection of fibroblast growth factor-2 (FGF2) or vehicle. Recent findings have shown that relearning and re-extinction, unlike initial learning and extinction, do not depend on NMDAr activation. Three experiments demonstrated that FGF2 prevents the switch from NMDAr-dependent to NMDAr-independent reacquisition and re-extinction, suggesting that FGF2 may lead to the partial erasure of the original fear memory. These findings add to a growing body of work suggesting that FGF2 may be a novel pharmacological enhancer of exposure therapy for humans with anxiety disorders. 相似文献
72.
We explored perspective-taking behavior in a visuospatial mental rotation task that requires listeners to adopt an egocentric or “other-centric” frame of reference. In the current task, objects could be interpreted relative to the point-of-view of the listener (egocentric) or of a simulated partner (other-centric). Across three studies, we evaluated participants’ willingness to consider and act on partner-specific information, showing that a partner’s perceived ability to contribute to collaborative mutual understanding modulated participants’ perspective-taking behavior, either by increasing other-centric (Study 2) or egocentric (Study 3) responding. Moreover, we show that a large proportion of participants resolved referential ambiguity in terms of their partner’s perspective, even when it was more cognitively difficult to do so (as tracked by online movement measures), and when the presence of a social partner had to be assumed (Studies 1 and 2). In addition, participants continued to consider their partner’s perspective during trials where visual perspectives were shared. Our results show that participants will thoroughly invest in either an other-centric or egocentric mode of responding, and that perspective-taking strategies are not always dictated by minimizing processing demands, but by more potent (albeit subtle) factors in the social context. 相似文献
73.
Facial expression and direction of gaze are two important sources of social information, and what message each conveys may ultimately depend on how the respective information interacts in the eye of the perceiver. Direct gaze signals an interaction with the observer but averted gaze amounts to "pointing with the eyes", and in combination with a fearful facial expression may signal the presence of environmental danger. We used fMRI to examine how gaze direction influences brain processing of facial expression of fear. The combination of fearful faces and averted gazes activated areas related to gaze shifting (STS, IPS) and fear-processing (amygdala, hypothalamus, pallidum). Additional modulation of activation was observed in motion detection areas, in premotor areas and in the somatosensory cortex, bilaterally. Our results indicate that the direction of gaze prompts a process whereby the brain combines the meaning of the facial expression with the information provided by gaze direction, and in the process computes the behavioral implications for the observer. 相似文献
74.
Rick Grush 《Synthese》2006,153(3):417-450
A number of recent attempts to bridge Husserlian phenomenology of time consciousness and contemporary tools and results from cognitive science or computational neuroscience are described and critiqued. An alternate proposal is outlined that lacks the weaknesses of existing accounts. 相似文献
75.
Marjukka Pajulo Nancy Suchman Mirjam Kalland Linda Mayes 《Infant mental health journal》2006,27(5):448-465
Substance abuse during early motherhood has become a significant problem and has led to accelerated efforts to develop specific treatment facilities for these mothers and children. Despite the often intensive treatment efforts in residential settings, there is surprisingly little evidence of their efficacy for enhancing the quality of caregiving. The situation of these mother‐child pairs is exceptionally complex and multilevel, and has to be taken into account in the content and structuring of treatment. Intensive work in the “here and now” focusing on the mother‐child relationship from pregnancy onwards in an effort to enhance maternal reflective capacity and mindedness is considered a key element for better treatment prognosis, in terms of both abstinence and quality of parenting. Pioneering work with such a focus is described in this article. 相似文献
76.
ABSTRACT— Real-time cognition is best described not as a sequence of logical operations performed on discrete symbols but as a continuously changing pattern of neuronal activity. The continuity in these dynamics indicates that, in between describable states of mind, mental activity does not lend itself to the linguistic labels relied on by much of psychology. We discuss eye-tracking and mouse-tracking evidence for this temporal continuity and provide geometric visualizations of mental activity, depicting it as a continuous trajectory through a state space (a multidimensional space in which locations correspond to mental states). When the state of the system travels toward a frequently visited region of that space, the destination may constitute recognition of a particular word or a particular object; but on the way there, the majority of the mental trajectory is in intermediate regions of that space, revealing graded mixtures of mental states. 相似文献
77.
Sylvia K. Harmon-Jones Rick Richardson 《British journal of psychology (London, England : 1953)》2022,113(2):455-478
Here, we examined retrospective reports of adults’ earliest autobiographical memory, the age of this report and whether the reported age was associated with exposure to early life adversity, current anxiety and childhood attachment. Across four studies, we found that reporting a later ‘earliest’ memory was associated with higher self-reported anxiety in both American (Studies 1, 2 and 4) and Australian (Study 3) samples. Furthermore, in Studies 2–4, we found that reporting a later earliest memory uniquely predicted anxiety when controlling for number of adverse childhood events (a risk factor for the development of anxiety). In Study 4, we established that this relation is partially mediated by childhood anxious attachment. Although we consistently demonstrated that later earliest memories were associated with current anxiety, we found little evidence for a relation between reported age at the time of earliest memory and childhood adversity. We also found no evidence of gender differences in the associations of interest. These results suggest that poorer memory of early childhood is associated with greater childhood anxious attachment and anxiety in adulthood. The implications of this work are discussed in terms of the adaptive nature of autobiographical memory and the development of a coherent life narrative. 相似文献
78.
79.
Michael T. Wojnowicz Melissa J. Ferguson Rick Dale Michael J. Spivey 《Psychological science》2009,20(11):1428-1435
ABSTRACT— How do minds produce explicit attitudes over several hundred milliseconds? Speeded evaluative measures have revealed implicit biases beyond cognitive control and subjective awareness, yet mental processing may culminate in an explicit attitude that feels personally endorsed and corroborates voluntary intentions. We argue that self-reported explicit attitudes derive from a continuous, temporally dynamic process, whereby multiple simultaneously conflicting sources of information self-organize into a meaningful mental representation. While our participants reported their explicit (like vs. dislike) attitudes toward White versus Black people by moving a cursor to a "like" or "dislike" response box, we recorded streaming x - and y -coordinates from their hand-movement trajectories. We found that participants' hand-movement paths exhibited greater curvature toward the "dislike" response when they reported positive explicit attitudes toward Black people than when they reported positive explicit attitudes toward White people. Moreover, these trajectories were characterized by movement disorder and competitive velocity profiles that were predicted under the assumption that the deliberate attitudes emerged from continuous interactions between multiple simultaneously conflicting constraints. 相似文献
80.
A differential reinforcement of low (DRL) rates procedure was implemented as a changing criterion design with positive punishment and response marking to reduce attention‐maintained behavior of screaming, profanity, and disruptive behaviors of three adolescent males. One participant was diagnosed with static encephalopathy and attention deficit hyperactivity disorder (ADHD) and severe mental retardation, the other two were diagnosed with Down syndrome, one with moderate mental retardation, and the other with severe mental retardation. Through response marking, a verbal warning was delivered immediately following the initial occurrence of a target behavior. A special token (positive punishment) was immediately delivered with a verbal cue and placed on a behavior board following the next occurrence of that behavior. Appropriate requests (hand‐raising) for attention was acknowledged and reinforced with verbal praise. The DRL procedure, combined with positive punishment and response marking, was successful in decreasing the frequency of targeted behaviors amongst all participants. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献