Effects of multiple exposures to D-cycloserine on extinction of conditioned fear in rats

Previous research has shown that an acute, post-training injection of D-cycloserine (DCS) facilitates extinction of conditioned fear in rats; however, the effects of multiple exposures to DCS in this situation are not known. In Experiment 1, rats were conditioned (light-shock pairings) and 24 h later given six extinction (light-alone) trials followed by an injection of DCS (15 mg/kg) or saline. The next day, all rats were tested for light-elicited freezing. In Experiment 2, the effect of DCS on extinction was tested in the same manner, except that rats were pre-exposed to DCS (0, 1, or 5 injections) just prior to conditioning. In Experiment 3, rats received five pre-exposures of DCS but conditioning occurred either 2 or 28 days after the last pre-exposure. The results showed that DCS facilitated extinction of conditioned freezing to the light CS when no drug pre-exposure had occurred, but pre-exposure to DCS just prior to conditioning disrupted the facilitation of extinction effect. When 28 days were interposed between pre-exposure and conditioning, the facilitatory effects of DCS on extinction were restored. These findings suggest that DCS has significant clinical value but that behavioral desensitization may occur with multiple exposures; however, desensitization is not permanent and is reduced by the passage of time.     

Don't stand so close to me: the effects fo self-construal in interpersonal closeness

Abstract— Three studies investigated the effects of self-construal activation on behavior conducive to interpersonal proximity. Study 1 revealed that compared with control participants, participants who were primed with the independent (or personal) self sat further away from where they anticipated another person would sit in a waiting room. Results of Study 2 indicated that participants primed with the interdependent (or social) self sat closer to the anticipated other person than did those primed with the independent self. Finally, Study 3 used the chronic self-construal of participants to predict the seating distance in dyadic settings. Results showed that greater independence of participants' self-construals was associated with greater spatial distance during the interaction. Together, the studies provide clear evidence that self-construal activation automatically influences interpersonal behavior as reflected in the actual distance between the self and others. Results are discussed in terms of the functions and motives connected to self-construals.     

Developmental outcome of drug-exposed children through 30 months: a comparison of Bayley and Bayley-II

This study examined the effects of the Bayley Scales of Infant Development (BSID) version on developmental outcomes among drug-exposed children, some of whom received an intervention. Developmental outcome was evaluated with the BSID at 12 and 18 months and with the BSID-II at 24 and 30 months. In the repeated measures analyses, children scored higher on the BSID Mental Developmental Index (MDI; p < .01) and Psychomotor Developmental Index (PDI; p < .01) than on the BSID-II MDI and PDI. Version x Time (p < .01) and Version x Group (p < .01) interactions were also found for the MDI but not the PDI. PDI scores decreased on both the BSID and the BSID-II (p < .01). Over the first 2 years postpartum, mean MDI and PDI scores decreased among these high-risk, drug-exposed children.     

Antecedents of sexual and non-sexual aggression in young Singaporean men

This study investigated factors that have previously been implicated in male sexual aggression towards women, using a structural equation modelling approach to assess their relative influence on sexually coercive behaviours in young Singaporean men. Variables were classified under three major headings: childhood experience, personality, and attitudes facilitating violence. Non-sexual aggression against women was included in order to investigate its relationship to sexual aggression as well as its own causal antecedents. Results suggest that sexual and non-sexual aggression have different antecedents, and confirm the primacy of sexual variables (sexual experience, child sexual abuse) as antecedents to sexual aggression. Contrary to the hypothesis that sexual aggression is primarily aggressive in motivation, belligerence exerted only indirect effects on sexual aggression. Attitudinal variables (e.g. attitudes supportive of sexual aggression) contributed modestly to sexual but not to non-sexual aggression. Antisociality exerted indirect effects on both sexual aggression (via sexual experience and acceptance of interpersonal violence) and on non-sexual aggression (via belligerence). Parental violence contributed exclusively to non-sexual aggression. Finally, some cross-cultural differences in sexually coercive behaviour are highlighted.     

Object-centered attention in 8-month-old infants

We examined the extent to which visual orienting in 8-month-old infants shows evidence of being guided by object-based representations. Infants’ preferences to look at conspicuous targets presented on one of two stationary objects were measured following an event (cue) which directed their covert attention to one of the objects. The results indicate that by 8 months of age a cue presented on one part of an object directs attention to the whole object (object-centered attention). This then affects responses to targets that appear elsewhere on the cued object.     

Racial Mistrust and Deviant Behaviors Among Ethnically Diverse Black Adolescent Boys1

While it has been suggested that mistrust of the dominant White society may be an important protective factor for some members of racial minorities, the question of whether mistrust may also be related to nonnormative behaviors among minority members has not been explored. Using survey data from Miami, Florida, this study empirically tests this hypothesis among a sample of African American, Haitian, and other Caribbean island Black adolescent boys. Bivariate analyses suggest a strong relationship between racial mistrust and conventional forms of delinquency for all three ethnic groups. These findings also held in multivariate analyses in which six traditional predictors of deviance were statistically controlled. The authors conclude that racial mistrust adds a new dimension to empirical prediction models. In addition, they conclude that issues associated with racial mistrust should be considered when developing and implementing prevention strategies.     

Brief report: A clinical tracking system for helping see the forest through the trees

Adults with developmental disabilities who display behavior disorders repressent some of our field's biggest challenges. Those who provide direct support for such individuals are sometimes frightened and often frustrated by the occurrence of these behaviors parrticularly if neither they nor the agencies for whom they work have been successful in alleviating them. Under such circumstances the agency may secure the services of a consultant. At such times the consultant may find it diffcult to obtain information [from which to generate plausible hypothese and design interventionl plans] that is not unduly influenced by the emotions of the moment. This article describes a stop-gap system that can be used under such circumstsances to gather and analyze valuable longitudinal behavioual ecological data. The basic assumptions and strategies of this system are explained and illustrated through three case studies.