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251.
Despite the fact that data and theories in the social, behavioural, and health sciences are often represented on an ordinal scale, there has been relatively little emphasis on modelling ordinal properties. The most common analytic framework used in psychological science is the general linear model, whose variants include ANOVA, MANOVA, and ordinary linear regression. While these methods are designed to provide the best fit to the metric properties of the data, they are not designed to maximally model ordinal properties. In this paper, we develop an order‐constrained linear least‐squares (OCLO) optimization algorithm that maximizes the linear least‐squares fit to the data conditional on maximizing the ordinal fit based on Kendall's τ. The algorithm builds on the maximum rank correlation estimator (Han, 1987, Journal of Econometrics, 35, 303) and the general monotone model (Dougherty & Thomas, 2012, Psychological Review, 119, 321). Analyses of simulated data indicate that when modelling data that adhere to the assumptions of ordinary least squares, OCLO shows minimal bias, little increase in variance, and almost no loss in out‐of‐sample predictive accuracy. In contrast, under conditions in which data include a small number of extreme scores (fat‐tailed distributions), OCLO shows less bias and variance, and substantially better out‐of‐sample predictive accuracy, even when the outliers are removed. We show that the advantages of OCLO over ordinary least squares in predicting new observations hold across a variety of scenarios in which researchers must decide to retain or eliminate extreme scores when fitting data.  相似文献   
252.
The prevalence of gun violence in the U.S. has resulted in extensive examination of structural covariates of gun crime. The potential influence of institutionally isolated youth and illegal gun availability remains unexplored. Similarly, studies that simultaneously examine the influence of structural disadvantage and Southern culture are scant. We examine the relationships between these measures and gun crime in a sample of U.S. cities (N = 189) through negative binomial regression of data from the NIBRS and ACS. We find illegal gun availability and structural disadvantage maintain direct relationships with city-level gun crime counts. We also report several significant moderated relationships.  相似文献   
253.
Previous work has demonstrated post-retrieval impairment in associative learning paradigms, including those mediated by drugs of abuse, using nonspecific β-adrenergic receptor (β-AR) antagonists. Remarkably little is known about the role of the specific β-AR subtypes, or other adrenergic receptors, in these effects. The current study examined the effects of β1 and β2, as well as α1-adrenergic receptor antagonism following retrieval of a cocaine conditioned place preference (CPP). We found that rats administered the β2 antagonist ICI 118,551 (8 mg/kg intraperitoneal [IP]) or the α1 antagonist prazosin (1 mg/kg IP) following a drug-free test for CPP showed attenuated preference during a subsequent test, while the β1 antagonist betaxolol (5 or 10 mg/kg IP) and a lower dose of prazosin (0.3 mg/kg IP) had no effect. Furthermore, post-test microinfusion of ICI 118,551 (6 nmol/side) or prazosin (0.5 nmol/side) into the basolateral amygdala (BLA) also impaired a subsequent preference. Systemic or intra-BLA ICI 118,551 or prazosin administered to rats in their home cages, in the absence of a preference test, had no effect on CPP 24 h later. ICI 118,551 also attenuated the FOS response in the BLA induced by the CPP test. These results are the first to demonstrate a role for α1- and β2-specific adrenergic mechanisms in post-retrieval memory processes. These systemic and site-specific injections, as well as the FOS immunohistochemical analyses, implicate the importance of specific noradrenergic signaling mechanisms within the BLA in post-retrieval plasticity.Substantial evidence indicates that information acquired during a learning event is initially plastic, at which time memory retention can be disrupted, but is strengthened by a time-dependent consolidation process (McGaugh 2000). Recent work has focused on retrieval-induced plasticity, a process by which changes in the retention of previously acquired information are possible. The notion of reconsolidation, one theoretical mechanism by which such changes may occur, suggests that a retrieved memory enters a labile state and is vulnerable to disruption (Sara 2000; Nader 2003). Although the theoretical mechanisms underlying reconsolidation remain unclear, the behavioral effects have been demonstrated across many different learning paradigms using a variety of pharmacological manipulations (for review, see Tronson and Taylor 2007; Diergaarde et al. 2008). Studies with aversive and appetitive preparations, including drug reward-mediated learning, have demonstrated that the noradrenergic system is important for these post-retrieval memory processes (Przybyslawski et al. 1999; Debiec and Ledoux 2004; Bernardi et al. 2006; Diergaarde et al. 2006; Robinson and Franklin 2007; Abrari et al. 2008; Fricks-Gleason and Marshall 2008; Milton et al. 2008). For example, using an animal model of cocaine-conditioned behaviors, Bernardi et al. (2006) demonstrated that systemic post-retrieval administration of propranolol impaired a subsequent conditioned place preference (CPP), suggesting that β-adrenergic receptors (β-ARs) play an important role in processes occurring following drug memory retrieval.However, most of what is known about the noradrenergic system in the memory processes that follow cued reminder trials comes from studies that use nonspecific β-AR antagonists, such as propranolol. As a consequence, several issues regarding ARs and post-retrieval memory processes remain unresolved. First, because propranolol has affinity for both β1- and β2-AR subtypes, it is unclear which subtype mediates these effects. To date, no studies have examined reconsolidation-like impairments using subtype-specific β-AR antagonists, which is important because more specific medications may be equally efficacious with less adverse effects. Second, no studies to date have examined α-ARs regarding a potential role in reconsolidation-like effects. α-ARs—specifically α1-ARs—have a demonstrated role in memory consolidation (Ferry et al. 1999a,b) and may also mediate post-retrieval processes. Third, although the BLA has had a demonstrated role in reconsolidation-like effects in numerous studies, the behavioral conditions during retrieval of drug-associated memories leading to gene expression within the basolateral amygdala (BLA) have not clearly been defined. Specifically, in the CPP paradigm used here, it is unclear whether exposure to a cocaine cue alone will induce gene expression or whether a preference for the drug-associated environment needs to be expressed for BLA involvement (Franklin and Druhan 2000; Miller and Marshall 2005).Understanding the role of specific adrenergic receptors in mediating post-retrieval memory processes is particularly important in drug-induced CPP. In humans, drug-associated stimuli can facilitate drug use (Gawin 1991; See 2005) or precipitate relapse following abstinence (O''Brien et al. 1992). Thus, pharmacotherapies targeting these memory processes would benefit from a clearer understanding of the specific receptors that mediate behavioral effects (Taylor et al. 2009).Here, we first examined the effects of systemic post-test β1-, β2-, and α1-AR antagonism on cocaine CPP. We then focused on the BLA due to its involvement in reconsolidation-like effects in drug learning paradigms (e.g., Lee et al. 2005), employing microinfusions of AR antagonists and measuring FOS immunoreactivity (FOS-IR) to examine the BLA as a potential site of AR-mediated impairments.  相似文献   
254.
Research typically reveals that individuals like an object more when a persuasive message convinces them that this object is pleasant. In this paper, two experiments were conducted to understand the influence of such message-induced affective-expectations on judgments of experienced affect following direct encounter with an alcohol type of drink. As predicted, before trying the drink, recipients of the positive-expectation message had more positive expectations than recipients of the negative-expectation message. After drinking, participants judged the beverage to elicit affect congruent with message-induced expectations to the extent they did not endorse a naïve theory that their affective expectations congruently influence their experienced affect. In contrast, after drinking, the effect of the message disappeared when participants did endorse this naïve theory. Moderation of these effects, as well as theoretical and practical implications, are addressed.  相似文献   
255.
The theory of probabilistic mental models (PMM; G. Gigerenzer, U. Hoffrage, & H. Kleinb?lting, 1991) has had a major influence on the field of judgment and decision making, with the most recent important modifications to PMM theory being the identification of several fast and frugal heuristics (G. Gigerenzer & D. G. Goldstein, 1996). These heuristics were purported to provide psychologically plausible cognitive process models that describe a variety of judgment behavior. In this article, the authors evaluate the psychological plausibility of the assumptions upon which PMM were built and, consequently, the psychological plausibility of several of the fast and frugal heuristics. The authors argue that many of PMM theory's assumptions are questionable, given available data, and that fast and frugal heuristics are, in fact, psychologically implausible.  相似文献   
256.
General action and inaction goals can influence the amount of motor or cognitive output irrespective of the type of behavior in question, with the same stimuli producing trivial and important motor and cognitive manifestations normally viewed as parts of different systems. A series of experiments examined the effects of instilling general action and inaction goals using word primes, such as "action" and "rest." The first 5 experiments showed that the same stimuli influenced motor output, such as doodling on a piece of paper and eating, as well as cognitive output, such as recall and problem solving. The last 2 experiments supported the prediction that these diverse effects can result from the instigation of general action and inaction goals. Specifically, these last 2 studies confirmed that participants were motivated to achieve active or inactive states and that attaining them decreased the effects of the primes on behavior.  相似文献   
257.
Four experiments studied the role of GABA(A) receptors in the temporal dynamics of memory retention. Memory for an active avoidance response was a nonmonotonic function of the retention interval. When rats were tested shortly (2 min) or some time (24 h) after training, retention was excellent, but when they were tested at intermediate intervals (1-4 h), retention was poor. Activity at GABA(A) receptors was critical for impairing memory retention at the intermediate intervals because injection of the GABA(A) receptor partial inverse agonist FG7142 prior to test significantly improved performance. These retention enhancing effects of FG7142 were dose-dependent and not due to any nonspecific effects of FG7142 on activity. Our results suggest that the temporal dynamics of memory retention may be caused by variations in neurotransmission through the GABA(A) receptor in the post-training period.  相似文献   
258.
Phenomenology and the Cognitive Sciences - The goal of this paper is to illuminate the connections between agency, perception, subjectivity, space and the body. Such connections have been the...  相似文献   
259.
Relative to previous research concerning the positive association between high-performance work systems (HPWS) and employees’ voice and helping, we examined a wider range of mediators reflecting employees’ ability, motivation, and opportunity to expand their citizenship-based role definitions. Trust in the supervisor was also investigated as a boundary condition on the relationships in question. Multisource data, collected in 4 waves, from 208 supervisor–employee dyads showed that employees’ efficacy, instrumentality, and autonomy perceptions concerning voice mediated the association between employee-experienced HPWS and expanded role definition for voice. Instrumentality mediated the relationship between employee-experienced HPWS and expanded role definition for helping. The positive links between employee-experienced HPWS and both supervisor-rated helping and voice were mediated by employees’ role definitions. Trust in the supervisor positively moderated the mediated effects.  相似文献   
260.
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