Relational responses in tests of transposition with Rhesus monkeys

Three adult Rhesus monkeys (Macaca mulatta), one with nonrelated discrimination learning experience and two experimentally naive, were trained to discriminate between two simultaneously presented stimuli differing only in height. After exceeding the learning criteria on a VR 4 reinforcement schedule and considerable overtraining, subjects were tested for transposition. Both upward and downward and near and far tests were administered to determine the effects of distance from the original training pair on the amount of transposition. In these tests, each of the 24 stimulus pairs contained one or more novel stimuli. Training trials were interpolated to avoid extinction effects and measures were taken to avoid motivational deficits or differential rewards during testing. All three subjects responded relationally at far as well as near distances from the original training pair. Stimulus generalization, on the basis of increments of association, was found to be an inferior explanation for these data. Slight decrements on far tests can be better explained in terms of the learning-performance distinction.     

Preattentive and cognitive effects on perceptual completion at the blind spot

Our findings indicate that preattentive processes, such as the filling in of homogeneously colored areas, discrete dots, or bars across the blind spot, take into account both the color and the form that stimulate the retina around the optic disk. Perceptual completion of the “junction” of two opposite colors facing each other on opposite sides of the blind spot was resolved by simultaneous segregation of the two colors at the location of a filled-in perpendicular line that suggested a boundary separating the two colors. Orientation preference and relative salience of one color versus the other determined which color was perceptually completed in a forced-choice situation that involved perceptual completion at the intersection of a cross formed by bars of opposite colors. A 1-min exposure to these stimuli presented an ambiguous situation for perceptual completion of either color within the blind spot, and resulted in a perceptual “flip-flop” from one color to the other, much like the phenomenon that occurs in figure reversal. Instructions to speed up this reversal process led to a fivefold reduction in latency to first reversal.     

Effects of a school-based cognitive-behavioral intervention for ADHD children

Two variations of school-based cognitive-behavioral training (CBT) program were compared to each other and to a waiting-list control condition in the treatment of children with attention-deficit hyperactivity disorder (ADHD). The experimental interventions included a multicomponent condition that provided coordinated training programs for parents, teachers, and children and a teacher-only condition that offered training for classroom teachers only. Evaluation of outcome occurred at pre-intervention, post-intervention and at 6-week followup periods. Depedent measures included classroom behavior observations, teacher ratings of child behavior, child self-report, and teacher ratings of adjustment. The multicomponent CBT condition was significantly better than the other conditions at improving observed off-task/disruptive behavior at post-test. This improvement was maintained at followup, although treatment condition differences were no longer significant. There were no treatment condition differences on any other measures at postintervention or followup. It was concluded that the intervention had minimal short-term effects on the ADHD children. The results are discussed within the context of several methodological limitations of the study which serve as proposals for continued research in this area.The authors gratefully acknowledge the support and assistance of the faculty and staff at Echo Park, Cedar Park and Westview Elementary Schools (Rosemount, MN, Independent School District), and the parents and children who participated in this study. The authors would also like to extent special thanks to the principals of these schools, Mr. Robert Keaton, Mr. William Mack and Mr. Marvin Skinner, and the school psychologists servicing these schools, Ms. Sheila Peterson, Ms. Ann O'Brien, and Mr. Mark Kaloski, for their commitment and service to children with attention-deficit hyperactivity disorder.     

Family work with victims and offenders in a secure unit

Two examples of family therapy in a secure unit for violent mentally ill offenders are described. The model used incorporated ideas from reparation schemes for victims and offenders in addition to an emphasis on the circumstances of the offence.     

Local and global mechanisms of one- and two-dimensional orientation illusions

One-dimensional (1-D) orientation illusions induced on a test grating by a tilted and-surrounding 1-D inducing grating have a well-known angular function that exhibits both repulsion and attraction effects. Two-dimensional (2-D) orientation illusions are those induced on a test grating by 2-D image modulation, such as a pair of superimposed inducing gratings at different orientations, usually orthogonal (a plaid). Given the known angular functions induced by the plaid component gratings, two hypotheses were developed that predicted different plaid-induced illusion functions. Hypothesis 1 states that the 1-D component-induced effects simply add linearly; Hypothesis 2 states that there is an additional mechanism that responds to the virtual axes of mirror symmetry of the plaid and adds to the effect. The data of two experiments were consistent with the predictions from the second hypothesis but not the first. Possible neural substrates of mechanisms that extract axes of symmetry are discussed; it is suggested that such global symmetry axes may underlie the perceived orientation of complex shapes.     

Order‐constrained linear optimization

Despite the fact that data and theories in the social, behavioural, and health sciences are often represented on an ordinal scale, there has been relatively little emphasis on modelling ordinal properties. The most common analytic framework used in psychological science is the general linear model, whose variants include ANOVA, MANOVA, and ordinary linear regression. While these methods are designed to provide the best fit to the metric properties of the data, they are not designed to maximally model ordinal properties. In this paper, we develop an order‐constrained linear least‐squares (OCLO) optimization algorithm that maximizes the linear least‐squares fit to the data conditional on maximizing the ordinal fit based on Kendall's τ. The algorithm builds on the maximum rank correlation estimator (Han, 1987, Journal of Econometrics, 35, 303) and the general monotone model (Dougherty & Thomas, 2012, Psychological Review, 119, 321). Analyses of simulated data indicate that when modelling data that adhere to the assumptions of ordinary least squares, OCLO shows minimal bias, little increase in variance, and almost no loss in out‐of‐sample predictive accuracy. In contrast, under conditions in which data include a small number of extreme scores (fat‐tailed distributions), OCLO shows less bias and variance, and substantially better out‐of‐sample predictive accuracy, even when the outliers are removed. We show that the advantages of OCLO over ordinary least squares in predicting new observations hold across a variety of scenarios in which researchers must decide to retain or eliminate extreme scores when fitting data.     

Re-Considering the Structural Covariates of Gun Crime: An Examination of Direct and Moderated Effects

The prevalence of gun violence in the U.S. has resulted in extensive examination of structural covariates of gun crime. The potential influence of institutionally isolated youth and illegal gun availability remains unexplored. Similarly, studies that simultaneously examine the influence of structural disadvantage and Southern culture are scant. We examine the relationships between these measures and gun crime in a sample of U.S. cities (N = 189) through negative binomial regression of data from the NIBRS and ACS. We find illegal gun availability and structural disadvantage maintain direct relationships with city-level gun crime counts. We also report several significant moderated relationships.     

Post-retrieval disruption of a cocaine conditioned place preference by systemic and intrabasolateral amygdala β2- and α1-adrenergic antagonists

Previous work has demonstrated post-retrieval impairment in associative learning paradigms, including those mediated by drugs of abuse, using nonspecific β-adrenergic receptor (β-AR) antagonists. Remarkably little is known about the role of the specific β-AR subtypes, or other adrenergic receptors, in these effects. The current study examined the effects of β₁ and β₂, as well as α₁-adrenergic receptor antagonism following retrieval of a cocaine conditioned place preference (CPP). We found that rats administered the β₂ antagonist ICI 118,551 (8 mg/kg intraperitoneal [IP]) or the α₁ antagonist prazosin (1 mg/kg IP) following a drug-free test for CPP showed attenuated preference during a subsequent test, while the β₁ antagonist betaxolol (5 or 10 mg/kg IP) and a lower dose of prazosin (0.3 mg/kg IP) had no effect. Furthermore, post-test microinfusion of ICI 118,551 (6 nmol/side) or prazosin (0.5 nmol/side) into the basolateral amygdala (BLA) also impaired a subsequent preference. Systemic or intra-BLA ICI 118,551 or prazosin administered to rats in their home cages, in the absence of a preference test, had no effect on CPP 24 h later. ICI 118,551 also attenuated the FOS response in the BLA induced by the CPP test. These results are the first to demonstrate a role for α₁- and β₂-specific adrenergic mechanisms in post-retrieval memory processes. These systemic and site-specific injections, as well as the FOS immunohistochemical analyses, implicate the importance of specific noradrenergic signaling mechanisms within the BLA in post-retrieval plasticity.Substantial evidence indicates that information acquired during a learning event is initially plastic, at which time memory retention can be disrupted, but is strengthened by a time-dependent consolidation process (McGaugh 2000). Recent work has focused on retrieval-induced plasticity, a process by which changes in the retention of previously acquired information are possible. The notion of reconsolidation, one theoretical mechanism by which such changes may occur, suggests that a retrieved memory enters a labile state and is vulnerable to disruption (Sara 2000; Nader 2003). Although the theoretical mechanisms underlying reconsolidation remain unclear, the behavioral effects have been demonstrated across many different learning paradigms using a variety of pharmacological manipulations (for review, see Tronson and Taylor 2007; Diergaarde et al. 2008). Studies with aversive and appetitive preparations, including drug reward-mediated learning, have demonstrated that the noradrenergic system is important for these post-retrieval memory processes (Przybyslawski et al. 1999; Debiec and Ledoux 2004; Bernardi et al. 2006; Diergaarde et al. 2006; Robinson and Franklin 2007; Abrari et al. 2008; Fricks-Gleason and Marshall 2008; Milton et al. 2008). For example, using an animal model of cocaine-conditioned behaviors, Bernardi et al. (2006) demonstrated that systemic post-retrieval administration of propranolol impaired a subsequent conditioned place preference (CPP), suggesting that β-adrenergic receptors (β-ARs) play an important role in processes occurring following drug memory retrieval.However, most of what is known about the noradrenergic system in the memory processes that follow cued reminder trials comes from studies that use nonspecific β-AR antagonists, such as propranolol. As a consequence, several issues regarding ARs and post-retrieval memory processes remain unresolved. First, because propranolol has affinity for both β₁- and β₂-AR subtypes, it is unclear which subtype mediates these effects. To date, no studies have examined reconsolidation-like impairments using subtype-specific β-AR antagonists, which is important because more specific medications may be equally efficacious with less adverse effects. Second, no studies to date have examined α-ARs regarding a potential role in reconsolidation-like effects. α-ARs—specifically α₁-ARs—have a demonstrated role in memory consolidation (Ferry et al. 1999a,b) and may also mediate post-retrieval processes. Third, although the BLA has had a demonstrated role in reconsolidation-like effects in numerous studies, the behavioral conditions during retrieval of drug-associated memories leading to gene expression within the basolateral amygdala (BLA) have not clearly been defined. Specifically, in the CPP paradigm used here, it is unclear whether exposure to a cocaine cue alone will induce gene expression or whether a preference for the drug-associated environment needs to be expressed for BLA involvement (Franklin and Druhan 2000; Miller and Marshall 2005).Understanding the role of specific adrenergic receptors in mediating post-retrieval memory processes is particularly important in drug-induced CPP. In humans, drug-associated stimuli can facilitate drug use (Gawin 1991; See 2005) or precipitate relapse following abstinence (O''Brien et al. 1992). Thus, pharmacotherapies targeting these memory processes would benefit from a clearer understanding of the specific receptors that mediate behavioral effects (Taylor et al. 2009).Here, we first examined the effects of systemic post-test β₁-, β₂-, and α₁-AR antagonism on cocaine CPP. We then focused on the BLA due to its involvement in reconsolidation-like effects in drug learning paradigms (e.g., Lee et al. 2005), employing microinfusions of AR antagonists and measuring FOS immunoreactivity (FOS-IR) to examine the BLA as a potential site of AR-mediated impairments.     

When the expectations from a message will not be realized: Naïve theories can eliminate expectation-congruent judgments via correction

Research typically reveals that individuals like an object more when a persuasive message convinces them that this object is pleasant. In this paper, two experiments were conducted to understand the influence of such message-induced affective-expectations on judgments of experienced affect following direct encounter with an alcohol type of drink. As predicted, before trying the drink, recipients of the positive-expectation message had more positive expectations than recipients of the negative-expectation message. After drinking, participants judged the beverage to elicit affect congruent with message-induced expectations to the extent they did not endorse a naïve theory that their affective expectations congruently influence their experienced affect. In contrast, after drinking, the effect of the message disappeared when participants did endorse this naïve theory. Moderation of these effects, as well as theoretical and practical implications, are addressed.