Scientific rewards and conflicts of ethical choices in human subjects research.

The primary responsibility of the American Psychological Association's (APA) Committee on Standards in Research (CSR) is to advise the APA on issues and standards related to the protection of human participants in psychological research. A related goal is to enhance the use of good ethical practices by APA members. The purpose of this article is to foster the view of research ethics not as an affront to the integrity of sound research, but as opportunities for scientific rewards, including increased understanding of the meaning of data, enhanced recruitment, and the inclusion of more representative samples. Three ethical practices are discussed as examples of this general premise: respect for confidentiality, use of debriefing, and assurance that participants are noncoerced volunteers. The Committee's intent is to promote consideration of these issues, not to promulgate specific guidelines or procedures.     

Preference can be more powerful than detection of oddity as a test of discriminability.

Subjects presented with sets of three samples, two of distilled water and one of tap water, were significantly more consistent in choosing the tap water as preferable than they were in identifying it as the odd sample in the set. The result is opposite to the prediction of high-threshold models of sensory discrimination, which say that if a difference is not noticed, preferences will be random, whereas if a difference is noticed, preferences may still be in either direction. The result can be quantitatively explained by a model advanced by Frijters to explain an analogous anomaly found with the triangle test used in the food industry. Applying his model to the observed proportions yields essentially equivalent estimates of sensory difference (d' = 1.5, approximately) from the two tasks, and a direction of preference almost unanimously in favor of the tap water that was used. Since the model predicts that the proportion of subjects choosing the odd item will depart further from chance in the preference task than in the oddity task, the former has greater power to reject the null hypothesis of no sensory difference if one exists and if preference is overwhelmingly in one direction.     

Erikson's life cycle theory and images of God

Human life is a God-ordained pilgrimage by which persons travel toward ever-expanding images of God that emerge from the universal pattern of developmental crises. Using the work of Erik Erikson on the human life cycle and the work of Donald Capps on human sin, the author presents a way to conduct pastoral diagnosis and to provide pastoral care. By accurately tracing a person's images of God back to their potentially unresolved developmental crises, the pastoral caregiver can reopen opportunities for further and healthier resolution of the crises.     

Cuing effects and associative information in recognition memory

Item recognition requires discrimination of studied words from nonstudied words. Associative recognition requires subjects to discriminate studied word groups from recombinations of words from different groups. Cued recognition requires the same old-new discrimination as item recognition, but list items are presented as cues along with the test item. The results from three experiments show (1) little or no effect of cuing for low-frequency words, but (2) positive cuing effects for high-frequency words; (3) increasing levels of overall performance with increases in study time, but (4) unchanging effects of cuing with study time; and (5) stronger positive cuing effects for two cues than for one cue. Five models (Independent Cue Model, Matrix model, MINERVA 2, SAM, and TODAM) were fit to the data of Experiment 1. Each model has trouble with at least one aspect of the results. Theoretical implications and modifications are discussed at length.     

An investigation into the relationship between perceived control,attitude variability and the consumption of two common foods

The study reported here takes its lead from the literatures which emphasize the importance of attitude variability and the role of perceived control over action. Within-person variability and perceptions of control are investigated in the context of people's attitudes towards the consumption of two common foods. The role of attitude ambivalence is also examined. The findings indicate that higher attitude variability is associated with weaker relationships between the components of the theory of reasoned action and that attitude variability is negatively related to perceived control. Moreover, perceived control is shown to be related to different sorts of control problem for different behaviours. It is advocated that a more in-depth assessment of attitude variability and the perceived control construct is merited and that recent calls for more serious examination of attitude ambivalence are well-founded.     

Single and combined effects of methylphenidate and behavior therapy on the classroom performance of children with attention-deficit hyperactivity disorder

Twenty-four boys with attention deficit-hyperactivity disorder (ADHD) participating in an intensive summer treatment program each received b.i.d. placebo and two doses of methylphenidate (MPH, 0.3 mg/kg and 0.6 mg/kg) crossed with two classroom settings: a behavior modification classroom including a token economy system, time out and daily home report card, and a regular classroom setting not using these procedures. Dependent variables included classroom observations of on-task and disruptive behavior, academic work completion and accuracy, and daily self-ratings of performance. Both MPH and behavior modification alone significantly improved children's classroom behavior, but only MPH improved children's academic productivity and accuracy. Singly, behavior therapy and 0.3 mg/kg PMH produced roughly equivalent improvements in classroom behavior. Further, the combination of behavior therapy and 0.3 mg/kg MPH resulted in maximal behavioral improvements, which were nearly identical to those obtained with 0.6 mg/kg MPH alone.The authors gratefully acknowledge the assistance of Patricia Donovan, Michelle Berry, Mary Ingram, Patricia Wells, Beth Gnagy, Karen Greenslade, Mary Hamilton, and the entire staff of the Western Psychiatric Institute and Clinic ADHD Summer Treatment Program.     

Design and implementation of a program for AIDS prevention in female prostitutes

The Companeros model of HIV infection prevention in Ciudad Juarez, Mexico, is presented as conceived by the National Institute of Drug Abuse (NIDA). 518 women who were IV drug users, sexual partners of drug addicts, or prostitutes were requested to participate, and 232 consented. Initial and follow-up AIDS assessments were utilized along with an assessment of sociodemographic variables, including knowledge, sexual behavior, use and abuse of drugs, and previous health history. Educative sessions about AIDs and sexually transmitted diseases (STDs) included group discussions and interaction, video watching, personal experiences, and sociodramas. 61% of prostitutes were 29, 12.6% were 13-19 years old, 31.1% were aged 30-39, and 8.9% were 40. 11% had no formal education, 58% had 6 years of primary and part of 3 years of secondary education, only 18.6% completed secondary education; and 13% had higher education. 19% lived in a hotel or shelter. Family disintegration reached 44%; these women did not live with their children. Only 5.2% thought they had excellent health, 51% said they had good health, 31% stated they had average health, and 12% admitted having had health problems. 14.6% had genital ulcers, 1.3% had herpes, 15% had gonorrhea, and 10% had syphilis. Since IV drug use among these women was almost nonexistent sexual relations constituted the principal risk factor. Responses to a questionnaire showed that the most frequent sexual behavior was vaginal penetration followed by fellatio; anal penetration was less common. 34.9% of the women practiced fellatio without protection, 16.3% had anal intercourse without protection. The proportion of AIDS cases in Mexico in women of reproductive age was growing at an exponential rate, possible because of misinformation about AIDS, a history of STDs, and a low rate of condom use.     

Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease.

Although visuoconstructive impairment has been reported in both Alzheimer's (DAT) and Huntington's (HD) disease, there is little knowledge concerning how this cognitive deficit differs quantitatively and qualitatively in these two progressive dementias. To address this issue, the present study compared performances on the Clock Drawing Test (CDT: command and copy) of 25 DAT patients, 25 equally demented HD patients, and 25 elderly normal controls (NC). In the command condition, both patients groups were significantly impaired compared to the NC group. Although there was no significant difference between DAT and HD patients' total quantitative scores, a qualitative error analysis revealed a number of dissociations between the two patient groups. Graphic difficulties, very common in HD patients, were virtually absent in DAT patients; in contrast, conceptual errors were almost exclusively seen in DAT patients and were related to the severity of their dementia. Perseveration and "stimulus-bound" responses were also more frequent in DAT patients, and both groups made visuospatial errors. In the copy condition, the DAT, but not the HD, patients evidenced a marked improvement in performance. These results indicate that while both DAT and HD patients have significant visuoconstructive difficulties even in the early stages of their disorders, the specific cognitive processes underlying their quantitative impairments are quite different. It is possible that the DAT patients' conceptual errors are yet another indicator of the deterioration of their semantic knowledge.     

On the Relation Between Time Perception and the Timing of Motor Action: Evidence for a Temporal Oscillator Controlling the Timing of Movement

Studies of time estimation have provided evidence that human time perception is determined by an internal clock containing a temporal oscillator and have also provided estimates of the frequency of this oscillator (Treisman, Faulkner, Naish, & Brogan, 1992; Treisman & Brogan, 1992). These estimates were based on the observation that when the intervals to be estimated are accompanied by auditory clicks that recur at certain critical rates, perturbations in time estimation occur. To test the hypothesis that the mechanisms that underlie the perception of time and those that control the timing of motor performance are similar, analogous experiments were performed on motor timing, with the object of seeing whether evidence for a clock would be obtained and if so whether its properties resemble those of the time perception clock. The prediction was made that perturbations in motor timing would be seen at the same or similar critical auditory click rates. The experiments examined choice reaction time and typing. The results support the hypothesis that a temporal oscillator paces motor performance and that this oscillator is similar to the oscillator underlying time perception. They also provide an estimate of the characteristic frequency of the oscillator.     

The social location of those holding antihomosexual attitudes

Using data from a 1985 national sample of over 2300 adults, an index of attitudes toward homosexuality was created from 13 different questions. Respondents were more likely to hold antihomosexual attitudes if they were politically conservative, religious, older, less educated, male, married or widowed, or from the South. The effects of religiosity were less pronounced among black respondents. In addition, middle-aged respondents were more liberal than younger or older respondents if they were college educated or black.