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The social adjustment of the adolescent offspring of parents with bipolar affective disorder (n=41) was compared to that of the offspring of parents with nonaffective psychiatric disorders (n=22) and the offspring of normal controls (n=26). In addition, the relationship between social adjustment and cyclothymia in offspring was determined. Social adjustment was assessed using the Life Activities Inventory, a new measure developed to assess social functioning in adolescents and young adults. Cyclothymia was assessed with the General Behavior Inventory. As a group, the offspring of bipolar parents did not differ significantly from either control group on social adjustment. However, the cyclothymic offspring of bipolar parents exhibited significantly poorer social adjustment than the noncyclothymic offspring of bipolars and the offspring of psychiatric and normal controls. These findings suggest that poor social functioning in the adolescent offspring of parents with bipolar illness may be associated with the early manifestations of affective disorder. In addition, these data indicate that despite its subsyndromal intensity, cyclothymia can result in significant social impairment.This study was supported in part by National Institute of Mental Health (NIMH) Research Grant MH-39782 to Daniel N. Klein and NIMH Grants MH-33083 and MH-37195 to Richard A. Depue.  相似文献   
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A method of hardware reaction timing with millisecond accuracy, using one of the Amiga’s CIA 8520 chips, is described. The registers of this chip can be set to enable cascaded timing that functions independently of the CPU and, thereby, avoids the problems of software timing in a multitasking environment. In addition, the interfacing of a pair of reaction-time keys to one of the Amiga’s game controller connectors and a program for polling this port for keypresses are described.  相似文献   
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This study evaluated the relative efficacy of long (1 minute) and short (15 seconds) durations of negative practice for reducing self-stimulatory leg pounding of a traumatically brain-injured adult. In individual social skill training classes, long negative practice and short negative practice were administered concurrently in an alternating treatments design. Generalization of treatment effects outside of training sessions was assessed during the client's lunch period. The results revealed that both durations of negative practice were equally effective in reducing leg pounding during training sessions. However, the effects of training did not generalize to settings in which the practice contingency was not enforced. Pounding was more frequent and negative practice somewhat less effective during periods of high social stimulation.  相似文献   
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