Optimism and coping as determinants of psychosocial adjustment to rheumatoid arthritis

Psychosocial adjustment in 66 patients with chronic rheumatoid arthritis, with a mean duration of 12 years with the disease, were evaluated in a prospective design, with 62% of the sample followed up 16 months later. It was predicted that dispositional optimism would predict adjustment over time and that perceived support and perceived control would be related to psychosocial adjustment at the time of concurrent measurement. At Time 1, psychosocial adjustment was associated with greater optimism and perceived support and less disability. Optimism at Time 1 was the only significant predictor of changes in adjustment at Time 2 controlling for Time 1 adjustment and Time 2 disability. It was found that optimism temporally precedes increases in psychosocial adjustment. In terms of coping strategies, wishful thinking was related to poorer social adjustment, whereas problem-focused coping was marginally related to positive adjustment. Neither coping strategy predicted adjustment across time. Optimism at Time 1 did predict problem-focused coping at Time 2. Perceived social support regarding a specific circumstance at a given point in time enables one to persist in solving a task. Interventions to enhance the quality of life of individuals coping with progressive deteriorative disease must look at the influence of their behavior and attitude on those who provide care for them.     

Data selection and responsible conduct: Was millikan a fraud?

This paper addresses a problem in reporting scientific research. The problem is how to distinguish between justifiable and unjustifiable data selection. Robert Millikan is notorious for an infamous remark that he used all his data when in fact he had used a selection. On this basis he has been accused of fraud. There is a tension here — historians and his defenders see his selection as understandable and legitimate, while current statements about the Responsible Conduct of Research imply his selection was illegitimate. This paper discusses two main issues that arise in assessing his conduct, whether he was intentionally misleading and whether he actually did mislead the scientific community about some facts of nature. It is argued that he was not intentionally misleading, and that it is unlikely that he misled the scientific community.     

Measuring and predicting the effects of alcohol consumption on contrast sensitivity for stationary and moving gratings

Contrast sensitivity was measured for 12 healthy young males while sober, after ingestion of an alcohol placebo, and after ingestion of alcohol (95% grain alcohol; mean estimated blood alcohol level = .088%). Observations were made for both stationary gratings and gratings that traveled through a circular path and required pursuit eye movements. The significant alcohol-related reduction in contrast sensitivity was 2.6 times greater for moving (.29-log-unit reduction) than for stationary gratings (.11-log-unit reduction). The loss in contrast sensitivity for the moving gratings of high spatial frequency (12 cpd) was particularly severe (.37 log unit). Estimated blood alcohol level was correlated with the loss in contrast sensitivity for moving gratings (r = .61), but not with the loss for stationary gratings. Estimated blood alcohol level was strongly correlated with the difference between the loss in contrast sensitivity to moving and stationary gratings (r = .75). These results are consistent with reports that alcohol consumption degrades the ability to make pursuit eye movements. Subjects’ perceived intoxication level was not a reliable predictor of any index of visual performance.     

Tests of human olfactory function: Principal components analysis suggests that most measure a common source of variance

It is not known whether nominally different olfactory tests actually measure dissimilar perceptual attributes. In this study, we administered nine olfactory tests, including tests of odor identification, discrimination, detection, memory, and suprathreshold intensity and pleasantness perception, to 97 healthy subjects. Aprincipal components analysis performed on the intercorrelation matrix revealed four meaningful components. The first was comprised of strong primary loadings from most of the olfactory test measures, whereas the second was comprised of primary loadings from intensity ratings given to a set of suprathreshold odorant concentrations. The third and fourth components had primary loadings that reflected, respectively, mean suprathreshold pleasantness ratings and a response bias measure derived from a yes/no odor identification signal detection task. In an effort to adjust for potential confounding influences of age, gender, smoking, and years of schooling on the component structure, a matrix of residuals from a multiple regression analysis, which included these variables, was also analyzed. A similar component pattern emerged. Overall, these findings suggest, in healthy subjects spanning a wide age range, that (1) a number of nominally distinct tests of olfactory function are measuring a common source of variance, and (2) some suprathreshold odor intensity and pleasantness rating tests may be measuring sources of variance different from this common source.