Stimulus generalization of conditioned taste aversion in rats

Relatively little information is available regarding the intradimensional stimulus generalization of conditioned taste aversion (CTA). Experiment 1 employed a between-groups generalization test to examine the extent to which conditioned flavor aversion to one sucrose solution generalized to other concentrations of sucrose in adult rats. Evidence of a gradient of aversion was obtained. Because generalization gradients in other tasks have been found to flatten over a retention interval, Experiment 2 investigated the effects of delayed testing (2, 7, or 21 days) upon the slope of the generalization gradient. The generalization gradient flattened at the intervals, suggesting that subjects forgot the specific attributes of the conditioning concentration and avoided generalized stimuli as if they were the original CS. Experiment 3 used a long delay between taste and toxicosis to degrade the associative contingency and found no evidence that the generalization gradients found in the first two experiments could be explained in terms of enhanced neophobia due to poisoning. These findings provide further evidence (cf. A. W. Logue, 1979, Psychological Bulletin, 86, 276-296; M. Domjan, 1980, in J. S. Rosenblatt, R. A. Hinde, C. Beer, & M. Busnel (Eds.), Advances in the study of behavior, Vol. 11, New York: Academic Press) that CTA shares a number of similarities with other learning processes. Further, they illustrate that stimulus forgetting can be detected in a paradigm considered relatively immune to retention loss.     

君子不忧不惧：君子人格与心理健康——自我控制与真实性的链式中介

基于儒学经典命题提出君子人格通过自我控制与真实性的链式中介对心理健康产生正向效应的假设, 运用多种方法进行验证(总样本量为1169)。结果表明, 君子人格正向预测同时测量的心理健康(研究1)和6个月后测量的自尊、核心自我评价、情感平衡, 负向预测心理症状(研究4); 君子人格正向预测自我控制特质(研究1)和自我控制决策(研究3和研究4), 受到情境模拟操纵的自我控制提升心理健康与真实性(研究2), 受到回忆启动操纵的真实性提升心理健康(研究3); 链式中介作用也得到了同时和跨时间点测量、统计控制和实验控制等多方法结果的支持。君子人格水平较高的人, 更易自我控制, 由此感到自己的行为与真实自我更加一致与贯通, 因此具有更积极的心理状态。     

Retrograde amnesia: forgetting back

Recently, the field of animal memory research has seen a resurgence of interest in the mechanisms underlying retrograde amnesia (RA) and in the use of RA as a technique for studying memory processes. A recent report from a major neuroscience lab, which demonstrated RA for an old reactivated memory, revitalized the debate regarding the widely accepted memory-consolidation theory of RA. Here, we discuss a number of the characteristics of RA and consider the findings that led to the development of the memory-consolidation hypothesis, as well as those suggesting an alternative retrieval-deficit explanation.     

论医学的人本体及其文化内核

人和"人的世界"是系统的存在与演化过程,人和"人的世界"是文化的世界和流变。人,是人和"人的世界"的本体,文化是人和"人的世界"的内核及其展开。医学世界也是系统的存在与演化过程,是医学文化的展开与流变。医学人是医学世界的本体,医学文化内核及其展开形成医学世界,医学世界是医学文化流变的世界。     

多通道变化盲:理论、方法与进展

人们在特定条件下通常难以探测到事物的变化,这种现象发生在视、听、触感觉通道分别称为变化盲视、变话盲听和变化盲触。文章主要对以下四个方面进行详细的探讨:变化盲视及视觉表征理论、变化盲听及听觉信息加工机制、变化盲触及体表空间表征、多通道变化盲及空间注意和空间表征跨通道一致性本质。此外,文章还对多通道变化盲的理论深度和拓展方向及相关应用研究进行了展望。     

腹膜间皮细胞EMT在腹膜纤维化中的研究进展及意义

腹膜透析是终末期肾衰患者肾脏替代治疗的重要手段,腹膜纤维化导致腹透效能下降及超滤衰竭,制约着腹膜透析的应用.腹膜间皮细胞上皮细胞间充质转化是腹膜纤维化的起始和可逆环节,因此预防和逆转EMT的发生发展可能是阻止和延缓腹膜纤维化、超滤衰竭的最佳策略,并将带来巨大的社会和经济效益.     

Hypothermia-induced anterograde amnesia: is memory loss attributable to impaired acquisition?

The present investigation examined whether the poor test performance observed in studies of anterograde amnesia reflects a memory deficit or is a by-product of weaker initial learning resulting from impaired sensory, motivational, or associative processes. Two experiments were performed which utilized latent extinction (Experiment 1) and delay of punishment (Experiment 2) manipulations in order to assess the nature of original learning in rats trained under either hypothermic (29 degrees C) or normothermic conditions. Results from both experiments provided evidence that hypothermia treatment administered prior to training had relatively little influence on the animal's ability to acquire a passive avoidance response. Therefore, the rapid forgetting observed in hypothermia-induced anterograde amnesia is most likely due to memory deficits rather than an artifact of poorer acquisition.