On the ethics of facial transplantation research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements usually applied to health care research. We summarize the achievements of transplant surgery to date, focusing in particular on the safety and efficacy of immunosuppressive medications. We also emphasize the importance of risk/benefit assessments that take into account the physical, aesthetic, psychological, and social dimensions of facial disfiguration, reconstruction, and transplantation. Finally, we maintain that the time has come to move facial transplantation research into the clinical phase.     

Ethical Issues and At-Risk Behaviors in Marriage and Family Therapy: A Qualitative Study of Awareness

This exploratory study investigated perceptions of and relationship with professional ethics of therapists-in-training. A focus group of marriage and family therapy doctoral students explored self-awareness and at-risk behaviors regarding ethical competence and compliance. A grounded theory analysis of data is presented as a conditional matrix, which offers a theory of development between therapists and their perception of ethics. The Practitioner-Relationship Ethics Model represents findings of interaction between confidence in ethical principles, field experience, use of justification, and at-risk behaviors. Implications and limitations of these findings are presented, as are suggestions for research.     

The role of cortical cholinergic pre- and post-synaptic receptors in taste memory formation

A number of studies have implicated cholinergic activity in the mediation of learning and memory processes. However, the specific role of muscarinic receptors in memory formation mechanisms is less known. The aim of the present study is to evaluate the effects of muscarinic antagonist M2 presynaptic receptor, AFDX-116 (0.5mM) and M1 and M3 post-synaptic receptor pirenzepine (100mM), as well as a non-selective muscarinic antagonist, scopolamine (136mM), in the insular cortex (IC) during acquisition and retrieval of conditioned taste aversion (CTA). In addition, we evaluate the effects of those antagonists in cortical ACh release by in vivo microdialysis and the effects on the induction of in vivo LTP in the BLA-IC projection. The results showed that the cortical microinjections of scopolamine and pirenzepine, but not AFDX-116, produced significant disruption in the acquisition of CTA, without effects during retrieval. Microinjections of scopolamine and AFDX-116 produced significant cortical ACh release, while infusions of pirenzepine did not produce any release. Application of scopolamine and pirenzepine diminished induction of LTP in the BLA-IC projection, but not AFDX-116, as compared with vehicle. The induction of BLA-CI LTP seems to be modulated by post-synaptic muscarinic acetylcholine receptors and not by pre-synaptic muscarinic receptors. These results suggest a differential involvement of cholinergic receptors during acquisition and retrieval of aversive memory formation, as well as a differential role of muscarinic receptors in the biochemical and electrophysiological processes that may underlay aversive memory.     

Gesture production and text structure

In the present pilot study, we examined the relationship between gesture and verbal production. Subjects were asked to read a story and then to narrate what they remembered. We analyzed verbal production according to Kintsch's procedure and obtained a list of hierarchically organized propositions that represented the meaning of subject's narration. Propositions were subdivided into High- and Low-level propositions. Further, we analyzed gesture production by identifying hand or arm movement that accompanied subject's narration. Each gesture was associated with the word simultaneously produced, and then with the proposition to which the word belonged. Analysis showed subjects were more likely to produce gestures in association with High- rather than with Low-level propositions. High-level propositions may elicit the production of gestures which, in turn, mark the importance of verbal meaning conveyed simultaneously.     

The Syzygy,Reformulation and New Perspectives: Dreams,Anima-Animus and Gender1

The main objective of this qualitative and quantitative research paper is to explore the occurrences and relations of the anima, animus and androgynous in dreams, with particular emphasis on the consideration of the androgynous in the human psyche. The sample consists of 9 series of dreams (141 dreams in total), from 9 dreamers, 7 women (female sex/gender) and 2 men (male sex/gender), aged 25–57, heterosexual, undergoing Jungian psychotherapy, and presenting couple-related themes. Statistical results and qualitative analysis offer new input for the re-vision of the classical anima-animus model, and the addition of in-depth explorations into the androgynous, paving the way for a new model of psychopathology and psychotherapeutic clinical work, in transition.     

Peer and Teacher-Selected Peer Buddies for Adolescents With Autism Spectrum Disorders: The Role of Social,Emotional, and Mentalizing Abilities

This study examined mentalizing abilities, social behavior, and social impact of adolescents who expressed the willingness to become peer buddies for adolescents with Autism Spectrum Disorders, and adolescents selected by their teachers and peers. Twenty-seven teachers and 395 adolescents from public high schools completed mentalizing abilities, social status, behavioral, and peer buddy nomination measures. Findings suggest that social status and preference play a significant role in the selection of peer buddies by both teachers and classmates. Furthermore, more advanced Theory of Mind (ToM) abilities and the engagement in prosocial behaviors differentiated peers selected as buddies from other classmates. When compared with nonparticipating students, adolescents who expressed willingness to participate were more often girls, and were more prosocial. Agreement between teacher and peer nominations of best peer was moderate.     

Cultural and communicative memories: contrasting Argentina’s 1976 coup d’état and the 2001 economic-political-social crisis

Studies on collective memory have recently addressed the distinction between cultural and communicative memory as a way to understand how the source of a memory affects its structure or form. When a groups’ memory is mediated by memorials, documentaries or any other cultural artifacts, collective memory is shaped by cultural memory. When it is based mostly in communication with other people, its source is communicative memory. We address this distinction by studying two recent events in Argentinean history: the 2001 economic-political-social crisis (communicative memory) and the 1976 coup (cultural memory). We also examine the political ideology and the type of memory involved in collective memory. The memory of the studied events may occur during the lifetime of the rememberer (Lived Memory) or refer to distant events (Distant Memory). 100 participants responded to a Free Recall task about the events of 2001 in Argentina. Narrative analysis allowed comparing these recalls with our 1976 study. Results show: 1) Cultural memories are more contextualised, more impersonal and less affective. 2) Communicative memories are more personal and affective. Study shows how collective memory form changes when it has a different prevalent source.     

Using Liberation Psychology and Dialectical Humanism to Understand Latinx Adolescents’ Life Satisfaction and Depressive Symptoms

The authors conducted a study to examine how the presence of meaning in life, search for meaning in life, hope, family importance, and enculturation influenced Latinx adolescent students’ depressive symptoms and life satisfaction. Two regression models revealed there was a statistically significant relationship between predictor variables, life satisfaction, and depression. The article concludes with a discussion regarding the importance of these findings and recommendations for practice and research. Los autores llevaron a cabo un estudio para examinar cómo la presencia de sentido en la vida, la búsqueda de sentido en la vida, la esperanza, la importancia de la familia y la enculturación influyeron en los síntomas depresivos y satisfacción vital de estudiantes adolescentes Latinx. Dos modelos de regresión revelaron que existe una relación estadísticamente significativa entre las variables de predicción, la satisfacción vital y la depresión. Este artículo concluye con una discusión en torno a la importancia de estos hallazgos, así como recomendaciones para la práctica y la investigación.     

Aging in cognitive control of social processing: evidence from the attention network test

ABSTRACT

Aging seems to be associated with impairment of attentional network functioning. It is not known whether social information can modulate this age-related decline. We used three variants of Attention Network test to examine the age-related decline of attentional effects in response to stimuli with and without social-cognitive content. Three groups of younger, middle-aged, and older participants performed the ANT, using fish, drawings, or photographs of faces looking to the left or right as target and flanker stimuli. The results showed that both executive attention and alerting were more resistant to the age-related decline with social stimuli and that orienting attention scores showed a progressive increase with age in the presence of this kind of stimuli. These findings underline the importance of social information in modulating and contrasting the age-related decline and support the status of human faces as a special class of visual stimuli for the human attentional systems.