Reinforcement in an in vitro analog of appetitive classical conditioning of feeding behavior in Aplysia: blockade by a dopamine antagonist

In a recently developed in vitro analog of appetitive classical conditioning of feeding in Aplysia, the unconditioned stimulus (US) was electrical stimulation of the esophageal nerve (En). This nerve is rich in dopamine (DA)-containing processes, which suggests that DA mediates reinforcement during appetitive conditioning. To test this possibility, methylergonovine was used to antagonize DA receptors. Methylergonovine (1 nM) blocked the pairing-specific increase in fictive feeding that is usually induced by in vitro classical conditioning. The present results and previous observation that methylergonovine also blocks the effects of contingent reinforcement in an in vitro analog of appetitive operant conditioning suggest that DA mediates reinforcement for appetitive associative conditioning of feeding in Aplysia.     

Triadic transferences of pathological family images

Traditionally, self-object and psychosexual transferences have been thought of as dyadic processes. This paper emphasizes the importance of seeing the triadic transferences that are contained within the more visible dyadic transferences. Triadic transferences are the partial recreation of replicas of pathological family images that were constructed from experiences with father-motherchild triads during childhood. Detecting them lessens the likelihood of therapeutic impasses occurring which resemble family of origin dyadic alliances. Childhood development and developmental arrest are discussed from a triadic perspective. In a healthy psychological family a triadic heterosexual family image is constructed which contains a triadic self and a resolved Oedipus.Revision of a paper presented at the 12th International Congress of the International Association for Child and Adolescent Psychiatry and Allied Professions, Kyoto, Japan, July 20, 1990. A preliminary version, entitled Triadic Transferences, was presented at the 12th Annual Meeting of the American Family Therapy Association, Philadelphia, PA, June 21, 1990.The masculine gender form is used for convenience, but with the recognition that statements apply to both genders.     

Effects of the medical resonance therapy music® on haemodynamic parameter in children with autonomic nervous system disturbances

The present investigation is dedicated to the effects of the Medical Resonance Therapy Music^® (MRT-Music) on basic haemodynamic parameter in children with transient arterial hypertension due to disturbances of the autonomic nervous system with different degrees of initial sympatheticotonia. After the nuclear accident at Chernobyl many children developed blood pressure too high for their age norm. Having already observed a decrease in high blood pressure in pregnant women during Medical Resonance Therapy Music (Gerasimovich, Einysh, 1999; Gerasimovich, Sidorenko, 1995; Sidorenko, Tetiorkina, Korotkov, 1997) we studied the effects of the Medical Resonance Therapy Music^® (MRT-Music) on such children—with very positive results: the treatment with the music preparations demonstrated a clear sympatholythic effect and led the disturbed haemodynamic state back to its healthy age norm.     

Effects of the medical resonance therapy music in the complex treatment of epileptic patients

The purpose of the study was to evaluate the effectiveness of Medical Resonance Therapy Music (MRT-Music) as a psycho-physiological method for the treatment of epilepsy in severe epileptic patients, whose attacks persevered despite comprehensive drug treatments. Under investigation were frequency and severity of epileptic attacks, the subjective state, the dynamics of the inter-paroxysmal symptoms and the individual parameters of the functional asymmetry of the brain (IPFA). Frequency and severity of the paroxysms changed positively in 80 percent of the cases: frequency of attacks were reduced by 75 percent and many attacks manifested in the form of abortive variants. The paroxysmal component, the degree of amnesia and the polymorphism of the attacks were reduced. Such positive changes were 4 times less frequent in the control group. Changes in subjective state were 90 percent positive: the patients felt more healthy, were calmer, had a better mood and fewer ups and downs in mood, released tension, and reduced unrest, wrath, and irritation. The evaluation of the Minnesota Multiphasic Personality Inventory (MMPI) showed clear improvements in the inter-paroxysmal clinical picture, particularly in those paramaters that characterise the general degree of sickness, psychasthenic and paranoid traits, hypochondria, aggression and depressive states. Similar positive changes in the control group were observed two times less frequently. The changes of the IPFA-values were positive in 73.3 percent of the patients (27.8 percent in controls), had differently directed shiftings, were dependent on the initial level, and were determined by the location of the epileptic focus. *** DIRECT SUPPORT *** A31BB039 00004     

Attentional Bias for Threat: Evidence for Delayed Disengagement from Emotional Faces

The present paper reports three new experiments suggesting that the valence of a face cue can influence attentional effects in a cueing paradigm. Moreover, heightened trait anxiety resulted in increased attentional dwell-time on emotional facial stimuli, relative to neutral faces. Experiment 1 presented a cueing task, in which the cue was either an "angry", "happy", or "neutral" facial expression. Targets could appear either in the same location as the face (valid trials) or in a different location to the face (invalid trials). Participants did not show significant variations across the different cue types (angry, happy, neutral) in responding to a target on valid trials. However, the valence of the face did affect response times on invalid trials. Specifically, participants took longer to respond to a target when the face cue was "angry" or "happy" relative to neutral. In Experiment 2, the cue-target stimulus onset asynchrony (SOA) was increased and an overall inhibition of return (IOR) effect was found (i.e., slower responses on valid trials). However, the "angry" face cue eliminated the IOR effect for both high and low trait anxious groups. In Experiment 3, threat-related and jumbled facial stimuli reduced the magnitude of IOR for high, but not for low, trait-anxious participants.These results suggest that: (i) attentional bias in anxiety may reflect a difficulty in disengaging from threat-related and emotional stimuli, and (ii) threat-related and ambiguous cues can influence the magnitude of the IOR effect.     

On the reality of the conjunction fallacy

Attributing higher "probability" to a sentence of form p-and-q, relative to p, is a reasoning fallacy only if (1) the word probability carries its modern, technical meaning and (2) the sentence p is interpreted as a conjunct of the conjunction p-and-q. Legitimate doubts arise about both conditions in classic demonstrations of the conjunction fallacy. We used betting paradigms and unambiguously conjunctive statements to reduce these sources of ambiguity about conjunctive reasoning. Despite the precautions, conjunction fallacies were as frequent under betting instructions as under standard probability instructions.     

Evidence for age-related equivalence in the directed forgetting paradigm

The directed forgetting paradigm involves, under particular experimental circumstances, inhibitory mechanisms, which operate to the successful forgetting of irrelevant words. The item-by-item cueing method (e.g., Basden & Basden, 1996) was used to investigate the directed forgetting effect in young and old adults. Processing of the experimental words was manipulated between subjects by asking participants to perform either a deep or a shallow orienting task on each word of the study list before the occurrence of the cue (to remember of to forget). Results indicated that the instruction to process deeply both to-be-remembered and to-be-forgotten words led to equivalent directed forgetting effects in young and old adults. These results are discussed with respect to the implications they have for the Inhibitory Deficit theory (e.g., Hasher & Zacks, 1988), which suggests that cognitive aging is mainly characterized by a reduction in the efficiency of inhibitory processes.     

Building Models for the Relationship Between Attitudes Toward Suicide and Suicidal Behavior: Based on Data from General Population Surveys in Sweden,Norway, and Russia

Our aim was to build a model delineating the relationship between attitudes toward suicide and suicidal behavior and to assess equivalence by applying the model on data from different countries. Representative samples from the general population were approached in Sweden, Norway, and Russia with the Attitudes Toward Suicide (ATTS) questionnaire. Data on experience of suicidal behavior among significant others and self‐reported suicidal expressions were also collected. Structural equation modeling resulted in gender and country specific models where experience of suicidal behavior among significant others and self‐reported suicidal expressions earlier in life predicted attitudes, and attitudes predicted current suicidal expressions. The models included the attitude factors acceptance of suicide, condemnation, and preventability; age and level of education were also incorporated. The different models reveal possible ways to better understand gender and culture‐specific paths between attitudes and suicidal behaviors, and their relevance in a suicide prevention context is considered.     

A Review of “Suicidal Intent” Within the Existing Suicide Literature

The results of a systematic literature review that investigated suicide intent are presented. Of the 44 relevant articles identified, 17 investigated the relationships between various suicide risk factors and suicide intent and 25 publications investigated the relationships between suicide intent and various suicide outcomes. Despite recent advancements in the definition and nomological validity of suicide intent, a high degree of variability in the empirical measurement and analysis of suicide intent was found. Such variability limits future research related to measuring suicidal risk and outcomes, reporting suicide intent, or the meaningful comparison of diagnostic approaches or treatments across multiple studies.