The picture superiority effect in recognition memory: A developmental study using the response signal procedure

Items studied as pictures are better remembered than items studied as words even when test items are presented as words. The present study examined the development of this picture superiority effect in recognition memory. Four groups ranging in age from 7 to 20 years participated. They studied words and pictures, with test stimuli always presented as words, and time to respond to test stimuli was manipulated. The picture superiority effect showed a clear developmental trend. In the condition in which participants had ample response time, a significant picture superiority effect appeared in all but the youngest group. With short response time, a significant picture superiority effect appeared only among 11- and 20-year-old groups, while a significant reverse of the picture superiority effect was detected in the youngest group. These results were interpreted as suggesting that different memory processes (familiarity and recollection) contribute differently to the picture superiority effect at different stages of development.     

Control and synchronization of laser bursting and its implications in neuroscience

We present experimental and numerical evidence of control and synchronization of burst events in modulated CO₂ lasers. Bursts appear randomly in each laser as trains of large amplitude spikes intercalated by a small amplitude chaotic regime. Experimental data and model display the frequency locking of bursts in a suitable interval of coupling strengths. The analogy with neuronal bursting will also be discussed in view of the role of bursting synchronization in cognitive functions.     

Is amenorrhea a clinically useful criterion for the diagnosis of anorexia nervosa?

Aim of the study was to evaluate the clinical characteristics and the treatment outcome of underweight patients with eating disorder (ED) not otherwise specified without amenorrhea (EDNOS-WA), compared with classical anorexia nervosa (AN) cases. Seventy-three consecutive female patients (57 AN, and 16 EDNOS-WA) were evaluated before and after a 20-week cognitive behaviour inpatient treatment (CBT-I). Assessment included anthropometry, the Eating Disorder Examination (EDE), the Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), and the Temperament and Character Inventory (TCI). At logistic regression analysis, amenorrhea was only predicted by baseline BMI and intense exercise, not by psychopathological variables. Response to CBT-I was good and similar between groups, without differences in the dropout rate or time-to-dropout. Our data lend support to the hypothesis that the criterion “amenorrhea” is of no clinical utility in the diagnosis and treatment of AN and could be removed in the forthcoming DSM-V proposal.     

Endocrinology of menopausal transition and its brain implications

The central nervous system is one of the main target tissues for sex steroid hormones, which act on both through genomic mechanisms, modulating synthesis, release, and metabolism of many neuropeptides and neurotransmitters, and through non-genomic mechanisms, influencing electrical excitability, synaptic function, morphological features, and neuron-glia interactions. During the climacteric period, sex steroid deficiency causes many neuroendocrine changes. At the hypothalamic level, estrogen withdrawal gives rise to vasomotor symptoms, to eating behavior disorders, and altered blood pressure control. On the other hand, at the limbic level, the changes in serotoninergic, noradrenergic, and opioidergic tones contribute to the modifications in mood, behavior, and nociception. Hormone replacement therapy (HRT) positively affects climateric depression throughout a direct effect on neural activity and on the modulation of adrenergic and serotoninergic tones and may modulate the decrease in cognitive efficiency observed in climaterium. The identification of the brain as a de novo source of neurosteroids, suggests that the modifications in mood and cognitive performances occurring in postmenopausal women may also be related to a change in the levels of neurosteroids. These findings open new perspectives in the study of the effects of sex steroids on the central nervous system and on the possible use of alternative and/or auxiliary HRT.     

Plotinus’ Account of the Cognitive Powers of the Soul: Sense Perception and Discursive Thought

This paper focuses on Plotinus?? account of the soul??s cognitive powers of sense perception and discursive thought, with particular reference to the treatises 3. 6 [26], 4. 4 [28] and 5. 3 [49] of the Enneads. Part 1 of the paper discusses Plotinus?? direct realism in perception. Parts 2 and 3 focus on Plotinus?? account of knowledge in Enneads 5. 3 [49] 2?C3. Plotinus there argues that we make judgements regarding how the external world is by means of discursive reasoning. This latter claim, however, is in tension with what Plotinus argues elsewhere regarding our perceptual apprehension of the external world (3. 6 [26] 1; 4. 4 [28] 23). This puzzle is addressed in Part 3 of the paper, which investigates Plotinus?? view that there exist some sense perceptions of which we are unaware. Finally, Part 4 looks at Plotinus?? understanding of Plato??s famous wax block analogy, in 5. 3 (49). The overall conclusion of the paper is that Plotinus?? account of knowledge is radically different from that of the Cartesian tradition.     

In vitro analog of classical conditioning of feeding behavior in aplysia

The feeding behavior of Aplysia californica can be classically conditioned using tactile stimulation of the lips as a conditioned stimulus (CS) and food as an unconditioned stimulus (US). Moreover, several neural correlates of classical conditioning have been identified. The present study extended previous work by developing an in vitro analog of classical conditioning and by investigating pairing-specific changes in neuronal and synaptic properties. The preparation consisted of the isolated cerebral and buccal ganglia. Electrical stimulation of a lip nerve (AT4) and a branch of the esophageal nerve (En2) served as the CS and US, respectively. Three protocols were used: paired, unpaired, and US alone. Only the paired protocol produced a significant increase in CS-evoked fictive feeding. At the cellular level, classical conditioning enhanced the magnitude of the CS-evoked synaptic input to pattern-initiating neuron B31/32. In addition, paired training enhanced both the magnitude of the CS-evoked synaptic input and the CS-evoked spike activity in command-like neuron CBI-2. The in vitro analog of classical conditioning reproduced all of the cellular changes that previously were identified following behavioral conditioning and has led to the identification of several new learning-related neural changes. In addition, the pairing-specific enhancement of the CS response in CBI-2 indicates that some aspects of associative plasticity may occur at the level of the cerebral sensory neurons.     

Beyond the Psychosexual: The Body–Mind Relationship Discussion of “Somatic Experiencing”

The author discusses the importance of focusing on the body in analytic work since it functions as an important springboard for the patient to discover his or her unique existence. It also helps develop a dialogue between the mind and the body’s sensory level. This is a more archaic domain than the more often emphasized psychoanalytic tradition of organizing our thinking psychosexually. The author also underscores the differences between psychoanalysis and Somatic Experiencing and the risks and advantages of modulating or heightening sensory experience.