Creative thinking in adolescents with attention deficit hyperactivity disorder (ADHD).

A widened attentional focus, that is typically associated with ADHD, has been postulated to be accompanied by enhanced creative ability. However, creativity has been only limitedly examined in ADHD. Performance across several creativity measures were investigated in three groups: adolescents with ADHD, those with conduct disorder, and a healthy control sample. The ADHD group exhibited selective cognitive advantages and disadvantages by demonstrating an enhanced ability in overcoming the constraining influence of examples, but a reduced capacity to generate a functional invention during an imagery task. These findings are interpreted with reference to inhibitory control mechanisms and the contextual modulation of creative cognition.     

Determinants of lexical access in speech production: Role of word frequency and age of acquisition

The main determinants of lexical access in speech are considered to be a word's age of acquisition (AoA) and its frequency of occurrence in a speaker's experience. It is unclear whether and how these variables interact, although they are commonly observed to be correlated, for the few studies that address the issue have reported inconsistent findings. An influential view of AoA in lexical processing (Ellis and Lambon Ralph, 2000) predicts stronger frequency effects for items acquired later in life than for those acquired at an early age. Five experiments were designed to investigate the possible interaction of AoA and frequency effects in speech. We found that the interaction between word frequency and AoA was not robust and that, contrary to expectation, the effect of word frequency was greater for words acquired earlier in life than for those acquired later. The implications of our findings are discussed.     

Vocational choice and career planning. Spanish adaptation of Holland's Self-Directed Search (SDS-R)

The Self-Directed Search is a career-planning guide that works similarly to a vocational and professional interests inventory. A preliminary study allows detection of 68 ítems that need to be rectified, since they do not meet psychometric and semantic criteria. The current study demonstrates reliability and validity of the new adaptation. It is applied to a sample of 1460 subjects from different educational levels. As for reliability, the discrimination index of the items and internal consistency of the scales have improved. Additionally, procedures performed to verify validity (content, construct and concurrent) demonstrate that the instrument has acceptable validity. On balance, we can conclude that the instrument has sufficient scientific and technical credibility for application to the Spanish population.     

Anxiolytic-like activity of SB-205384 in the elevated plus-maze test in mice

Recent studies point to a major role for alpha2-containing GABA-A receptors in modulating anxiety. However, the possible implication of GABA-A receptors containing the alpha3 subunit on anxiety is less known. The aim of this study was to examine the effects of SB-205384 (0.5-4 mg/kg, i.p.), an alpha3 subunit positive modulator of GABA-A receptor, on anxiety tested in the elevated plus-maze in male mice, using classical and ethological parameters. Mice treated with SB-205384 showed an increase in the frequency of entries and the time spent in open arms, as well as a reduction in the time spent in closed arms, as compared with the control group. A notable increase of "head-dipping" unprotected and a reduction of "stretched-attend posture" protected was also evident. These findings indicate that SB-205384 exhibits an anxiolytic-like profile in the elevated plus-maze test, suggesting that GABA-A receptors which contain the alpha3 subunit might be involved in regulation of anxiety.     

Determinants of instrumental extinction in terrestrial toads (Bufo arenarum)

Previous research in a water-reinforced instrumental training situation with toads (Bufo arenarum) has shown that performance in both acquisition and extinction is poorer after partial, rather than continuous reinforcement training. In Experiment 1, the performance of a group receiving 24 trials on a 50% partial reinforcement schedule was poorer in acquisition and extinction than that of continuously reinforced groups matched for trials or reinforcements. However, partially reinforced toads extinguished at the same rapid rate as a continuously reinforced group that received training only on the days in which the partial toads received water reinforcement. In Experiment 2, extinction was faster after 10 reinforced acquisition trials than after 30 trials. This evidence suggests that the deleterious effects of partial reinforcement in toads can be explained by a combination of two factors, namely, the distribution of reinforced trials across days and the total number of reinforcements.     

Cortical memory mechanisms and language origins

We have previously proposed that cortical auditory-vocal networks of the monkey brain can be partly homologized with language networks that participate in the phonological loop. In this paper, we suggest that other linguistic phenomena like semantic and syntactic processing also rely on the activation of transient memory networks, which can be compared to active memory networks in the primate. Consequently, short-term cortical memory ensembles that participate in language processing can be phylogenetically tracked to more simple networks present in the primate brain, which became increasingly complex in hominid evolution. This perspective is discussed in the context of two current interpretations of language origins, the "mirror-system hypothesis" and generativist grammar.