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111.
Floridi’s work, although diverse and multifaceted, portrays a solid coherence across his different lines of work. Among his wealth of interests and results, we highlight his recent work on information logics, on the ethics of information technology, and his rigorous (and vigorous) philosophical analysis of recent technological trends and developments in information technology. In the present article we illustrate, by means of some connecting arguments, the diversity and coherence of Floridi’s work. We also show how his work, although fundamentally philosophical in nature, can be used to build solid foundations for scientific and entrepreneurial endeavours of higher quality. More specifically, we discuss how the combination of results from the three lines of work referred to above can be used as ground for the organisation of higher quality programmes to augment the capabilities and effectiveness of governmental systems through information and communications technology, a trend that has been explored in many nations and that has been coined Electronic Government. Electronic Government programmes that improve the capabilities of citizens to interact with each other and with governments, as well as the capabilities of governments to listen to the needs and aspirations of citizens, have the potential to contribute to the construction of more democratic states. Electronic Government systems that rely on ready made models to prescribe to citizens how best they should interact with each other and with the public administration are, however, by construction non-democratic. Hence, it can be a moral and ethical matter for governments to choose which line of technological development they take.  相似文献   
112.
In this cross-sectional study we analyzed the links between marital quality and intimacy, body image, and psychological quality of life (PQoL) of breast cancer patients, as well as the moderating role of cancer phase (treatment, survivorship) on the aforementioned links. We also evaluated whether body image mediated the associations between marital relationship variables and PQoL. An analysis of the data from 128 patients (66 undergoing treatment, 62 survivors) indicated that the majority of links between variables were significant only during the treatment phase. Mediating effect of body image on the associations between relationship variables and PQoL was found only at the treatment phase.  相似文献   
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Excitation of the mesocorticolimbic pathway, originating from dopaminergic neurons in the ventral tegmental area (VTA), may be important for the development of exaggerated fear responding. Among the forebrain regions innervated by this pathway, the amygdala is an essential component of the neural circuitry of conditioned fear. The functional role of the dopaminergic pathway connecting the VTA to the basolateral amygdala (BLA) in fear and anxiety has received little attention. In vivo microdialysis was performed to measure dopamine levels in the BLA of Wistar rats that received the dopamine D(2) agonist quinpirole (1 μg/0.2 μl) into the VTA and were subjected to a fear conditioning test using a light as the conditioned stimulus (CS). The effects of intra-BLA injections of the D(1) antagonist SCH 23390 (1 and 2 μg/0.2 μl) and D(2) antagonist sulpiride (1 and 2 μg/0.2 μl) on fear-potentiated startle (FPS) to a light-CS were also assessed. Locomotor performance was evaluated by use of open-field and rotarod tests. Freezing and increased dopamine levels in the BLA in response to the CS were both inhibited by intra-VTA quinpirole. Whereas intra-BLA SCH 23390 did not affect FPS, intra-BLA sulpiride (2 μg) inhibited FPS. Sulpiride's ability to decrease FPS cannot be attributed to nonspecific effects because this drug did not affect motor performance. These findings indicate that the dopamine D(2) receptor pathway connecting the ventral tegmental area and the basolateral amygdala modulates fear and anxiety and may be a novel pharmacological target for the treatment of anxiety.  相似文献   
115.
How can we identify and estimate workers’ tacit knowledge? How can we design a personnel mix aimed at improving and speeding up its transfer and development? How is it possible to implement tacit knowledge sustainable projects in remote areas? In order to answer these questions, it is necessary to distinguish between types of tacit knowledge, to establish what they allow for and to consider their sources. It is also essential to find a way of managing the tacit knowledge ‘stock’ and distribution within the workforce. In short, a conceptual framework is needed to manage tacit knowledge. Based on previous works and 2 years of action research, this paper introduces such a framework and describes its partial application to support the pre-operational training and hiring in a large industrial plant in Brazil. Two contributions emerge from the research. First, the concept of ‘levels of similarity’ is introduced as a means to qualify the experience of workers and estimate the associated tacit knowledge. Second, the capability of carrying out three types of judgement properly and speedily is put forward as being a core ability of those who possess what has been called ‘collective tacit knowledge’ (Collins in Organ Stud 28(2):257–262, 2007). In practical terms, the results indicate the opportunity for companies to capitalize on the experience and tacit knowledge of their workers in a systematic way and with due recognition. Ultimately, positive impacts are expected in their absorptive capacity as well as in their management and human resources systems, accident prevention, productivity and the development of sustainable projects in remote areas.  相似文献   
116.
The lateral and basolateral nuclei of the amygdala (LaA and BLA, respectively) serve as a filter for unconditioned and conditioned aversive information that ascends to higher structures from the brainstem, whereas the central nucleus of the amygdala (CeA) is considered to be the main output for the defense reaction. It has been shown that the dorsal periaqueductal gray (dPAG) is activated by threatening stimuli and has important functional links with the amygdala through two-way anatomical connections. In this work, we examined the influence of chemical inactivation of these nuclei of amygdala on the freezing and escape responses induced by electrical stimulation through electrodes implanted in the dPAG of Wistar rats. Each rat also bore a cannula implanted in the LaA, BLA or CeA for injections of muscimol (0.5 microg/0.5 microL) or its vehicle. The duration of freezing behavior that outlasts electrical stimulation of the dPAG was also measured. On the following day, these animals were submitted to a contextual fear-conditioning using foot shocks as unconditioned stimulus. Conditioned freezing to contextual cues previously associated with foot shocks was also inhibited by injections of muscimol into these amygdaloid nuclei. The contextual conditioned freezing behavior is generated in the neural circuits of conditioned fear in the amygdala. The data obtained also show that injections of muscimol into the three amygdaloid nuclei did not change the aversive threshold of freezing, but disrupted the dPAG post-stimulation freezing. Previous findings that the latter freezing results directly from dPAG stimulation and that it is not sensitive to a context shift suggest that it is unconditioned in nature. Thus, the amygdala can affect some, but not all, aspects of unconditioned freezing. Post-stimulation freezing may reflect the process of transferring aversive information from dPAG to higher brain structures.  相似文献   
117.
The aim of this study is twofold: on the one hand, to determine how visual space, as assessed by exocentric distance estimates, is related to physical space. On the other hand, to determine the structure of visual space as assessed by exocentric distance estimates. Visual space was measured in three environments: (a) points located in a 2-D frontoparallel plane, covering a range of distances of 20 cm; (b) stakes placed in a 3-D virtual space (range = 330 mm); and (c) stakes in a 3-D outdoors open field (range = 45 m). Observers made matching judgments of distances between all possible pairs of stimuli, obtained from 16 stimuli (in a regular squared 4 x 4 matrix). Two parameters from Stevens' power law informed us about the distortion of visual space: its exponent and its coefficient of determination (R2). The results showed a ranking of the magnitude of the distortions found in each experimental environment, and also provided information about the efficacy of available visual cues of spatial layout. Furthermore, our data are in agreement with previous findings showing systematic perceptual errors, such as the further the stimuli, the larger the distortion of the area subtended by perceived distances between stimuli. Additionally, we measured the magnitude of distortion of visual space relative to physical space by a parameter of multidimensional scaling analyses, the RMSE. From these results, the magnitude of such distortions can be ranked, and the utility or efficacy of the available visual cues informing about the space layout can also be inferred.  相似文献   
118.
The main purpose of the present study was to investigate whether in natural environment, using very large physical distances, there is a trend to overconstancy for distance estimates during development. One hundred and twenty-nine children aged 5 to 13 years old and twenty-one adults (in a control group), participated as observers. The observer's task was to bisect egocentric distances, ranging from 1.0 to 296.0 m, presented in a large open field. The analyses focused on two parameters, constant errors and variable errors, such as measuring accuracy and precision, respectively. A third analysis focused on the developmental pattern of shifts in constancy as a function of age and range of distances. Constant error analysis showed that there are two relevant parameters for accuracy, age, and range of distances. For short distances, there are three developmental stages: 5-7 years, when children have unstable responses, 7-11, underconstancy, and 13 to adulthood, when accuracy is reached. For large distances, there is a two-stage development: 5-11 years, with severe underconstancy, and beyond this age, with mild underconstancy. Variable errors analyses indicate that precision is noted for 7 year-old children, independently of the range of distances. The constancy analyses indicated that there is a shift from constancy (or slightly overconstancy) to underconstancy as a function of physical distance for all age groups. The age difference is noted in the magnitude of underconstancy that occurs in larger distances, where adults presented lower levels of underconstancy than children. The present data were interpreted as due to a developmental change in cognitive processing rather than to changes in visual space perception.  相似文献   
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The study explored the association between the perceptions 175 Chilean business students held about their parents' acceptance of academic dishonesty and their self-reports of academic dishonesty. Regressing scores for parental acceptance onto self-reported academic dishonesty indicated it accounted for a small (2.2%) but significant amount of variance beyond demographic and academic performance variables. Effect size analysis based on structure coefficients indicated that parental acceptance was the second best predictor in the equation, suggesting that parental acceptance is a correlate that merits further study.  相似文献   
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