Broadening of activity with flow across neural structures

Synfire chains have long been suggested as a substrate for perception and information processing in the nervous system. However, embedding activation chains in a densely connected nervous matrix risks spread of signal that will obscure or obliterate the message. We used computer modeling and physiological measurements in rat hippocampus to assess this problem of activity broadening. We simulated a series of neural modules with feedforward propagation and random connectivity within each module and from one module to the next. We found that activity broadened as it propagated from one module to the next. This occurred over a wide array of parameters with greater broadening seen with increasing excitatory-excitatory synaptic strength. Activity broadening correlated positively with propagation velocity. Multi-electrode measurements of activity propagation in disinhibited CA1 slice demonstrated broadening of about 50% over 1 mm. Such broadening is a problem for information transfer that must be dealt with in a fully functioning nervous system.     

Do aggressive people play violent computer games in a more aggressive way? Individual difference and idiosyncratic game-playing experience.

ABSTRACT This study investigates whether individual difference influences idiosyncratic experience of game playing. In particular, we examine the relationship between the game player's physical-aggressive personality and the aggressiveness of the player's game playing in violence-oriented video games. Screen video stream of 40 individual participants' game playing was captured and content analyzed. Participants' physical aggression was measured before the game play. The results suggest that people with more physical-aggressive personality engage in a more aggressive style of playing, after controlling the differences of gender and previous gaming experience. Implications of these findings and direction for future studies are discussed.     

培训迁移影响因素研究述评

对培训迁移的研究从关注培训本身发展到关注培训以外影响其效果的因素,且焦点集中在对于企业来说更可控的因素上,主要是迁移气氛与组织特征。培训迁移气氛包括情境线索与结果两个维度。该文分析了影响培训迁移的几个主要因素,并根据已有的研究,提出了培训迁移研究未来的方向,例如,组织和个人的职业生涯管理与培训迁移的关系,以及培训类型的扩展对培训迁移带来的影响     

Online interpretation of scalar quantifiers: insight into the semantics-pragmatics interface

Scalar implicature has served as a test case for exploring the relations between semantic and pragmatic processes during language comprehension. Most studies have used reaction time methods and the results have been variable. In these studies, we use the visual-world paradigm to investigate implicature. We recorded participants’ eye movements during commands like “Point to the girl that has some of the socks” in the presence of a display in which one girl had two of four socks and another had three of three soccer balls. These utterances contained an initial period of ambiguity in which the semantics of some was compatible with both characters. This ambiguity could be immediately resolved by a pragmatic implicature which would restrict some to a proper subset. Instead in Experiments 1 and 2, we found that participants were substantially delayed, suggesting a lag between semantic and pragmatic processing. In Experiment 3, we examined interpretations of some when competitors were inconsistent with the semantics (girl with socks vs. girl with no socks). We found quick resolution of the target, suggesting that previous delays were specifically linked to pragmatic analysis.     

Father, Mother and Me: Parental Value Orientations and Child Self-identity in Asian American Immigrants

Relations between Asian American parental value orientations and children’s self-identity in the domains of achievement and relationship were examined. Sixty-nine Asian American youths (15 males) of East Asian origin (51 Chinese, 18 Koreans) interviewed their parents (30 fathers) for their life stories as first-generation Asian Americans. They also told their life stories as second-generation Asian Americans. Fathers and mothers upheld Confucian values, which were associated with children’s autonomous sense of self in achievement domain and relational sense of self in relationship domain. Furthermore, fathers and mothers had differential influences on children’s self-identity, and sons and daughters responded differently to parental value socializations. Findings are discussed with respect to parent–child relationships and continuity of ethnic values in contemporary Asian American families.     

民族认同在民族间态度中的积极作用

社会认同理论提出后,民族认同与民族间态度的关系受到社会心理学家的关注。社会认同理论认为群体认同是群体间态度的基础,过分的民族认同容易产生消极的民族间态度。而发展取向研究认为民族认同与积极的民族间态度的具有正向关系,研究者通过一系列的研究发现,发展成熟的民族认同与积极的民族间态度具有正相关的关系。     

治疗糖尿病创新药物研究

本论文从治疗2型糖尿病药物应用现状出发,通过对2型糖尿病病理的认识,新发现的主要受体和相关药靶等方面进行分析。指出随着对糖尿病认识的深入发展,治疗糖尿病创新药物研究的发展趋势也发生了相应的变化,就是从局部治疗到全身综合考虑,从药物外部直接地干预到增强自身调节功能。为治疗2-型糖尿病药物发展指明了方向。     

系统论引领帕金森病治疗思路

帕金森病的病因不单是多巴胺的缺失或减少,西医学的多巴胺替代疗法忽略了帕金森痛发病的复杂性和整体性;中医的辨证论治缺乏对系统内部的深入研究,带有很大的主观性和盲目性.而在系统论指导下的结构还原,深化了对帕金森病的中西医发病机制的系统认识.中西医结合治疗是还原论和系统论的统一,是帕金森病系统治疗的最佳形式.     

循证医学与实事求是

循证医学主张"慎重、准确和明智地应用当前所能获得的最好的研究依据;结合临床医生的个人专业技能和多年临床经验;考虑患者的价值扣愿望,将三者完美地结合制定出患者的治疗措施."贯穿着临床医学对患者进行"以人为本"科学救死扶伤的实事求是理念.要使"循证医学"卓有成效,应当抓住二大关键:实事求是,维护"证据"的真实性,提高医术的可靠性.     

经尿道前列腺电切术中保温与否对患者凝血功能的比较

探讨经尿道前列腺电切术(TURP)中实施保温治疗对凝血功能的影响.60例TURP患者,随机分为加压空气调温毯保温组(Ⅰ组)和对照组(Ⅱ组).观察体温、血浆凝血酶原时间(PT)、部分激活凝血活酶时间(APTT)、纤维蛋白原(FIB)、血小板计数(PLT)、血红蛋白(Hb)和红细胞压积(Hot)的变化.结果显示Ⅱ组手术后体温明显低于手术前(P<0.05).Ⅱ组术后各时点与T0相比PT、APTT明显延长,FIB和PLT显著降低(P<0.05);Ⅱ组与Ⅰ组各时点相比PT、APTT明显延长,FIB和PLT显著降低(P<0.05).认为TURP期间实施加压空气调温毯保温治疗能维持机体凝血功能稳定,心脏事件发生率较低.