Anhedonia is a transdiagnostic symptom found in patients with schizophrenia and depression. Current pharmacological interventions for anhedonia are unsatisfactory in a considerable proportion of patients. There has been growing interest in applying noninvasive brain stimulation (NIBS) to patients with anhedonia. However, evidence for the efficacy of NIBS for anhedonia remain inconsistent. This study systematically identified all studies that measured anhedonia and applied NIBS in patients with schizophrenia or depression. We conducted a search using the various databases in English (PubMed, EBSCOHost (PsycInfo/PsycArticles), Web of Science) and Chinese (China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform) languages, and reviewed original research articles on NIBS published from January 1989 to July 2023. Our search had identified 15 articles for quantitative synthesis, with three concerning schizophrenia samples, 11 concerning samples with depression, and one concerning both clinical samples. We conducted a meta-analysis based on the 15 included studies, and the results suggested that NIBS could improve anhedonia symptoms in schizophrenia patients and patients with depression, with a medium-to-large effect size. Our findings are preliminary, given the limited number of included studies. Future NIBS research should measure anhedonia as a primary outcome and should recruit transdiagnostic samples. 相似文献
By defining the essence of a policy problem, an issue frame shapes how individuals think about a political issue. In this research, we investigate framing effects among domain experts, an understudied yet increasingly important set of individuals in the policymaking process. Because domain experts have extensive and highly structured knowledge on a particular topic, they are likely to actively process issue frames to which they are exposed. Consequently, we hypothesize that frames consistent with experts' values will be particularly influential, whereas frames inconsistent with their values will lead to contrast effects. We test our hypotheses on a unique set of domain experts by examining professional farmers' attitudes toward no‐till agriculture. Using an experimental design, we find evidence that environmental values interact with frames to influence farmers' interest in no‐till, especially when farmers are exposed to a novel frame. 相似文献
Based on data from the 2014 Communities that Care Youth Survey, the authors examine the associations between drug use frequencies among 11 drugs. This research represents a step in determining what leads to the use of dangerous drugs like heroin, other opioids, and other not so dangerous substances. Findings indicate the highest association is between marijuana and alcohol use. Most drugs show at least a low to medium association with all other drugs. Findings indicate the difficulty in making gateway assumptions and that poly-drug use determined by peer associations is a better explanation. 相似文献
The purpose of this study was to evaluate auditory feedback for dance students on a competition team in which one peer provided auditory feedback to another peer for a selected dance movement. Some peers switched roles during the study, and increases in their performances were evaluated both as the receiver and deliverer of auditory feedback. All participants demonstrated increases in their respective target behaviors when they received auditory feedback. Several participants also displayed increases in their movements when they provided auditory feedback to their peer partner, although these increases were not as substantial as those who received feedback. 相似文献
Objective: The recommended dose of cyproterone acetate (CPA), an anti-androgen that is commonly used in the hormonal treatment of transgender women, is 50–100 mg daily. Our objective was to determine whether CPA at 25 mg daily would suppress total testosterone as effectively as 50 mg daily in transgender women.
Methods: We conducted a retrospective cohort analysis of transgender women attending an endocrinology clinic between April 1, 2009, and June 30, 2015. We used a generalized linear mixed model to compare total testosterone between patients on CPA 25 mg versus CPA 50 mg or higher. In a subgroup of patients for which the CPA dose was decreased from 50 mg to 25 mg, we compared total testosterone levels before and after the decrease.
Results: We divided the sixty-eight patients included in the study into 4 groups: group 1, CPA 25 mg (N =31); group 2, CPA 50 mg or higher (N = 19); group 3, CPA dose lowered from 50 mg to 25 mg (N = 15); group 4, CPA dose increased from 25 mg to 50 mg (N = 3). The mean total testosterone on treatment was 0.9 nmol/L (95% CI 0.7 to 1.1) in group 1 and 1.2 nmol/L (95% CI 0.9–1.5) in group 2 and were not significantly different (p = 0.087). In group 3, there was no significant difference between total testosterone levels before and after decreasing the dose of CPA from 50 mg to 25 mg, p = 0.86. Group 4 was excluded from analysis.
Conclusions: We found that 25 mg of CPA daily was effective at suppressing testosterone levels to within normal female range when used in combination with recommended estrogen therapy in transgender women. Clinicians should consider using a lower dose of CPA in order to minimize potential adverse effects. 相似文献
Despite well-documented post-adoption needs of adoptive families, most states provide no or very limited post-adoption services. This study describes Right Turn® (RT), a state-wide program for strengthening adoptive families and preventing adoption dissolution. Results suggest: (a) RT is serving its targeted audience of adoptive families with challenging problems indicated by older adopted children with a history of multiple placements, extended time in social services systems, and a host of mental health challenges; and (b) adoption training, family support when navigating access to post-adoption services, and collaboration with adoption-competent therapists appeared to have helped improve program outcomes. 相似文献
Objective: Previous research has provided evidence that colour associations and frame can influence behavioural intentions to engage in vaccination behaviours. In this study, the extension of these effects to sunscreen application behaviours was investigated. Additional colours and the manner in which colour primes were employed were also explored.
Design: Two hundred and eighty-six college students were primed with either short wavelength colours (blue/purple) or long wavelength colours (red/orange) as part of goal framed sunscreen information pamphlets.
Main outcome measures: Self-reported behavioural intentions to apply sunscreen, immediate affective reaction to stimuli material, anticipated affect towards sunscreen use, and perceived efficacy of preventing skin cancer were measured.
Results: Individuals with no prior intention to use sunscreen expressed greater behavioural intentions to do so after reading a positively framed sunscreen pamphlet that was designed using short wavelength colours. The negatively framed messages and those presented in long wavelength colours did not enhance persuasion.
Conclusions: In accordance with the Unification Theory of Framing, a match between the representations of the target behaviour, the colour prime, and the frame resulted in the greatest amount of persuasion. Creating communications with representations that match the target behaviour could be a powerful tool to increase compliance. 相似文献
