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Frontostriatal networks play critical roles in grounding action semantics and syntactic skills. Indeed, their atrophy distinctively disrupts both domains, as observed in patients with Huntington's disease (HD) and Parkinson's disease, even during early disease stages. However, frontostriatal degeneration in these conditions may begin up to 15 years before the onset of clinical symptoms, opening avenues for pre‐clinical detection via sensitive tasks. Such a mission is particularly critical in HD, given that patients’ children have 50% chances of inheriting the disease. Against this background, we assessed whether deficits in the above‐mentioned domains emerge in subjects at risk to develop HD. We administered tasks tapping action semantics, object semantics, and two forms of syntactic processing to 18 patients with HD, 19 asymptomatic first‐degree relatives, and sociodemographically matched controls for each group. The patients evinced significant deficits in all tasks, but only those in the two target domains were independent of overall cognitive state. More crucially, relative to controls, the asymptomatic relatives were selectively impaired in action semantics and in the more complex syntactic task, with both patterns emerging irrespective of the subjects’ overall cognitive state. Our findings highlight the relevance of these dysfunctions as potential prodromal biomarkers of HD. Moreover, they offer theoretical insights into the differential contributions of frontostriatal hubs to both domains while paving the way for innovations in diagnostic procedures.  相似文献   
73.
The use of personality disorder (PD) categories persists, despite the evidence against them. An often overlooked reason for this is the fact that the true structure underlying the Diagnostic and Statistical Manual of Mental Disorders (DSM) taxonomy is still unknown: We cannot be certain which disorders are valid, and which ones are arbitrary mixtures of heterogeneous traits. To address this gap, we factor analyzed the Personality Diagnostic Questionnaire (PDQ–4+; Hyler, 1994 Hyler, S. E. (1994). PDQ–4+ Personality Diagnostic Questionnaire–4+. New York, NY: New York State Psychiatric Institute. [Google Scholar]) at the criterion level in a mixed clinical and nonclinical sample of 2,519 individuals. The resulting structure was more similar to current dimensional taxonomies than to the DSM classification at all hierarchical levels. Whereas paranoid and antisocial PDs—and to a lesser extent avoidant, dependent, depressive, and schizoid PDs—were fairly homogeneous, all other disorders turned out to be combinations of 2 or 3 unrelated dimensions. Our results strongly support the structure of empirically based dimensional taxonomies and relocate DSM criteria within this emerging framework, thus contributing to preserving much of the knowledge accumulated to date.  相似文献   
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The history of organizations and collectives is something alive. It is a network of memories, actions, collaborations, dreams, encounters, and disconnections that live within each of its members. The EcoDialogue Center is an academic space of the University of Veracruz for promoting dialogue between disciplines. In this article we are presenting the stories, both personal and collective, and the values and ideals that create our Center. We are using this opportunity to reflect on the cultural, geographical, emotional, intellectual, and societal conditions that have allowed this innovative process within the rules and customs of a university.  相似文献   
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In this essay, I focus on two biographical works by Hannah Arendt and Simone de Beauvoir that I read as political texts: Rahel Varnhagen: The Life of a Jewess (Arendt 1957 ) and “Must We Burn Sade?” (Beauvoir 2012 ). Reading Arendt's Varnhagen and Beauvoir's “Sade” side by side illuminates their shared preoccupation with lived experience and their common political premises: the antagonism between freedom and sovereignty, and the centrality of action and constructive relations with others. My argument is that these texts constitute an original style of political thinking, which I call politico‐biographical hermeneutics, or reading the life of others as exercises in political theory. Politico‐biographical hermeneutics, as I take it, is not a systematic methodology, but an approach to interpreting sociopolitical forces as they come to bear and are embodied and inscribed in the lived experiences, struggles, and works of representative or exemplary individuals. This approach identifies the political lessons of lived experience and supports one of the central claims of feminist philosophy, namely, that the personal and the political are not antithetical, but relational.  相似文献   
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Differences in the processing of emotions like fear and sadness have important implications for our understanding of many psychological phenomena (e.g., attentional biases, psychopathology). The late positive potential (LPP) is an established event-related potential that reflects motivated attention to emotional stimuli at the neural level with excellent temporal resolution, but has been infrequently used to study differences across emotions. Drawing on functional theories of emotion suggesting that the quick processing of fear-inducing stimuli increases chances of survival, we hypothesized that fear-inducing pictures would produce larger LPP amplitudes compared to other emotions (happy and sad) in the early time windows of the LPP (e.g., 400–700, 700–1000 ms). The results supported our hypothesis, offering new, albeit preliminary, evidence of the differential processing of threat-related stimuli on the LPP.  相似文献   
78.
Recent research indicates that people consistently make others feel a certain way (e.g. happy or stressed). This individual difference has been termed affective presence, but little is known about its correlates or consequences. The present study investigated the following: (i) whether affective presence influences others' romantic interest in a person and (ii) what types of people have positive and negative affective presence. Forty volunteers took part in a speed‐dating event, during which they dated six or seven opposite‐sex partners. A Social Relations Model analysis confirmed that individuals prompted consistent positive emotional reactions in others. Participants were more likely to want to see dates with greater positive affective presence again in the future, and positive affective presence explained the effects of perceived responsiveness on romantic interest. Associations between positive affective presence and trait predictors, including emotion regulation, emotional expressiveness, attachment style, agreeableness and extraversion, were also observed. The findings indicate that what emotionally distinguishes one individual from another lies in part in the emotional consequences of their behaviours on others. © 2013 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology.  相似文献   
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Using longitudinal data collected at four time points from 191 dyads of Mexican‐origin adolescent first‐time mothers and their mother figures, we examined changes in and socialization of traditional gender role attitudes across the transition to parenthood using latent growth curve modeling and actor – partner interdependence modeling. Longitudinal growth models indicated that, regardless of nativity status, adolescent mothers' and their foreign‐born mother figures' gender role attitudes became more egalitarian across adolescents' transition to parenthood, spanning from the 3rd trimester of pregnancy to 36 months postpartum. Furthermore, actor‐partner interdependence modeling suggested that adolescents' and their mother figures' gender role attitudes during adolescents' third trimester of pregnancy equally contributed to subsequent increases in one another's gender role attitudes at 10 months postpartum. Importantly, this reciprocal socialization process was not moderated by adolescent mothers' nor by their mother figures' nativity status. Findings suggest that it is important to understand the cultural and intergenerational family processes that contribute to the development of gender role attitudes during the transition to parenthood for adolescent mothers and their mother figures in Mexican‐origin families.  相似文献   
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