Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH+, and 10 without, WMH−) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH+ and WMH− - in right parietal and bilateral temporal areas. Both WMH− and WMH+ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH+ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood. 相似文献
Philosophia - (Dellsén, Philosophical Studies, 177(12), 3661–3678, 2020) argues that a positivistic defense of science’s objectivity is incoherent because bias in the... 相似文献
The study of the bifactor structure of psychopathology, which includes a general factor of psychopathology (or p factor) in addition to the internalizing and externalizing factors, has gained attention. However, its associations with the Five-Factor Model (FFM) of personality has been addressed in few studies, and none has examined different plausible etiological models (i.e., continuity, pathoplasty, complication) to explain its relationship, which is the aim of the present research. Additionally, the longitudinal association of the General Factor of Personality (GFP) and the p factor will be also explored. Personality and psychopathological symptoms of high school students were assessed at three time points (once a year) (n?=?655; M?=?13.79, SD?=?1.24; 49.8% girls). Confirmatory Factor Analysis (and measurement invariance across waves) were tested for the traits, the GFP and the bifactor model of psychopathology. While the bifactor model and the one-factor solution for each personality trait displayed good fit to the data and remained invariant over time, the structure of the GFP was adequate and invariant in two of the three waves. The resulting factors were included in cross-lagged panel models and showed that the FFM traits and the psychopathology factors influenced each other reciprocally. Most associations fell in line with the continuity model, but minor pathoplastic and complication effects were also reported. Similar associations were found between the GFP and the p factor. These results suggest that interventions in riskier personality profiles might prevent the development of general and more specific psychopathology spectra.
Argumentation - Minimal adversariality consists in the opposition of contradictory conclusions in argumentation, and its usual metaphorical expression as a game between combating arguers has seen... 相似文献
Animal Cognition - The present study was conducted to assess the context specificity of latent inhibition (LI) in the snail Cornu aspersum, using the appetitive Pavlovian Conditioning procedure of... 相似文献
Gender is recognized as an important social determinant of health, but past research on gender differences in psychological well-being have not produced conclusive results. This study investigated gender differences in eudaimonic well-being and life satisfaction in emerging adulthood. A cross-sectional study with a sample of 1990 emerging adults (50% males) from the Spanish general population was conducted. Participants were assessed through five questionnaires. Results showed that women scored higher than men in purpose in life and personal growth. Hierarchical multiple regression analysis revealed that the most important predictors of emerging adult men’s and women’s eudaimonic well-being and life satisfaction were higher self-confidence and lower negative self-evaluation. Other significant variables in the eudaimonic well-being of both women and men were higher score in the masculine/instrumental trait, higher emotional social support, higher educational level, and higher score in the feminine/expressive trait. Furthermore, higher instrumental social support was associated with eudaimonic well-being in females. Other predictors of women’s and men’s life satisfaction were higher score in the feminine/expressive trait, less age, higher educational level and higher instrumental social support. In addition, higher emotional social support was associated with life satisfaction in males. The results suggest that gender is important in the psychological well-being of people in emerging adulthood, although self-esteem and instrumental social support are, in both emerging adult women and men, the most important predictors of psychological well-being.
Addressing spirituality with clients from diverse spiritual backgrounds is a facet of culturally competent and ethical practice, yet various obstacles contribute to spirituality being overlooked. This article features a counseling technique used with clients who are experiencing difficulty with issues of a spiritual nature. Based on constructivist principles, the tree ring technique provides a context and process for examining clients’ spiritual conflicts, whereby the client is the expert and the counselor adopts a not‐knowing stance. 相似文献
Interoceptive exposure (IE) is a standard component of cognitive-behavioural therapy (CBT) for panic disorder and agoraphobia. The virtual reality (VR) program ‘Panic-Agoraphobia’ has several virtual scenarios designed for applying exposure to agoraphobic situations; it can also simulate physical sensations. This work examines patients' acceptability of the IE component as applied in two different ways: using VR versus traditional IE. Additionally, it explores the relationship between users' treatment expectations and satisfaction and clinically significant change. Results showed that VR and traditional IE were well accepted by all participants. Furthermore, treatment expectations predicted efficacy. 相似文献
Status is a valued workplace resource that facilitates career success, yet little is known regarding whether and how cultural orientation affects status attainment. We integrate status characteristics theory with the literature on individualism and collectivism and propose a cultural patterning in the determinants of status. Four studies (N = 379) demonstrate that cultural orientation influences the tendency to view high status individuals as competent versus warm (Study 1), uncover cultural differences in both individuals’ tendency to engage in competence and warmth behaviors to attain workplace status (Study 2) and evaluators’ tendency to ascribe status to individuals who demonstrate competence versus warmth (Study 3), and verify that cultural differences in the effects of competence and warmth on status perceptions, and in turn performance evaluations, generalize to real world interdependent groups (Study 4). Our findings advance theory on the cultural contingencies of status attainment and have implications for managing diversity at work. 相似文献