The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study

Amnestic mild cognitive impairment (aMCI) patients carry a greater risk of conversion to Alzheimer's disease (AD). Therefore, the International Working Group (IWG) on AD aims to consider some cases of aMCI as symptomatic prodromal AD. The core diagnostic marker of AD is a significant and progressive memory deficit, and the Free and Cued Selective Reminding Test (FCSRT) was recommended by the IWG to test memory in cases of possible prodromal AD. This study aims to investigate whether the performance on the FCSRT would enhance the ability to predict conversion to AD in an aMCI group. A longitudinal study was conducted on 88 aMCI patients, and neuropsychological tests were analysed on the relative risk of conversion to AD. During follow‐up (23.82 months), 33% of the aMCI population converted to AD. An impaired FCSRT TR was significantly associated with the risk of conversion to dementia, with a mean time to conversion of 25 months. The FCSRT demonstrates utility for detecting AD at its prodromal stage, thus supporting its use as a valid clinical marker.     

Self-Perceived Health among School-Aged Adolescents: a School-Based Study in Southern Brazil

This study identified which aspects regarding the dimensions of quality of life, in terms of body image, relationships with family and friends, rest and free time, school, well-being and lifestyles function as predictors of self-perceived health among school adolescents in the southern Brazil. The sample was composed of 3360 students, ninth graders in public schools in the metropolitan area of Porto Alegre/RS (Brazil). The instruments used were: a) Health Behaviour in School Children, b) Happiness Overall Life, c) Positive and Negative Affect Scale, d) General Health Questionnaire (GHQ-12), e) Brief Multidimensional Scale of Life Satisfaction in Students (BMSLSS), and f) Subscale of Cohesion of the Family Environment Scale (FES). Multiple linear regression analysis was conducted to identify the predictors of perceived health. The results revealed a model with nine predictor variables in the sense that being more satisfied with one’s own body, perceiving one’s eating habits as healthier compared to others of the same age, having a greater sense of happiness in their current life, being able to talk to one’s brothers/sisters about issues of concern, a perception of being thinner compared to other people of the same age, greater consumption of healthy food, greater presence of positive affects and being male contribute to a greater perception of health. The results show that, for this population, the health issues are beyond the concern over physical health or the presence or absence of symptoms, but also encompass behavioral, relational and psychological aspects, as well.

     

Family identity and severe mental illness: A thematic synthesis of qualitative studies

There is a growing amount of research showing that a shared social identity and the sense of belonging to a family have a potential effect on health. However, little is known about the effects of severe mental illness on family identity. The authors carried out this thematic synthesis based on a systematic review of literature on family narratives of severe mental illness and family identity. The main findings indicate that in many families (i) their identity—as a shared social identity—undergoes a transformation process by which the identity aspects of being a family are reinforced; (ii) family members often take on a caring role as their main family role; and finally, (iii) a cultural component shapes this transformation process. The authors describe implications for research and application in the mental health field. All in all, family identity is transformed by the experience of severe mental illness.     

Physical activity, sedentary leisure, short sleeping and childhood overweight

In this study, using the path analysis, the relation between physical activity, non-regulated activity, sedentary leisure, hours of sleeping, and the body mass index (BMI) was analyzed. The sample was made up of 103 students, 59 girls and 44 boys, aged between 9 and 10 1/2 years. An individual interview was performed in which the children were asked about the TV programs they watched each day of the week; the time they played with the console and the computer; the time dedicated to sports, games and other activities. The results showed that sedentary leisure (number of hours of TV, computer and console) maintains a significant and inverse relation with the hours of sleeping, non-regulated activity (games and others activities), and physical sport activity. The difference between the results of this study and the previous one is discussed, taking into account the recruitment procedure of the participants.     

External support for collaborative problem solving in a simulated provider/patient medication scheduling task

Taking medication requires developing plans to accomplish the activity. This planning challenges older adults because of age-related cognitive limits and inadequate collaboration with health providers. The authors investigated whether an external aid (medtable) supports collaborative planning in the context of a simulated patient/provider task in which pairs of older adults worked together to create medication schedules. Experiment 1 compared pairs who used the medtable, blank paper (unstructured aid), or no aid to create schedules varying in complexity of medication constraints (number of medications and medication co-occurrence restrictions) and patient constraints (available times during the day to take medication). Both aids increased problem-solving accuracy and efficiency (time per unit accuracy) compared to the no-aid condition, primarily for more complex schedules. However, benefits were similar for the two aids. In Experiment 2, a redesigned medtable increased problem-solving accuracy and efficiency compared to blank paper. Both aids presumably supported problem solving by providing a jointly visible workspace for developing schedules. The medtable may be more effective because it externalizes constraints (relationships between medication and patient information), so that participants can more easily organize information. (PsycINFO Database Record (c) 2008 APA, all rights reserved).     

Evidence for the thalamic targets of the medial hypothalamic defensive system mediating emotional memory to predatory threats

Previous studies from our laboratory have documented that the medial hypothalamic defensive system is critically involved in processing actual and contextual predatory threats, and that the dorsal premammillary nucleus (PMd) represents the hypothalamic site most responsive to predatory threats. Anatomical findings suggest that the PMd is in a position to modulate memory processing through a projecting branch to specific thalamic nuclei, i.e., the nucleus reuniens (RE) and the ventral part of the anteromedial nucleus (AMv). In the present study, we investigated the role of these thalamic targets in both unconditioned (i.e., fear responses to predatory threat) and conditioned (i.e., contextual responses to predator-related cues) defensive behaviors. During cat exposure, all experimental groups exhibited intense defensive responses with the animals spending most of the time in the home cage displaying freezing behavior. However, during exposure to the environment previously associated with a cat, the animals with combined RE + AMv lesions, and to a lesser degree, animals with single AMv unilateral lesions, but not animals with single RE lesions, presented a reduction of contextual conditioned defensive responses. Overall, the present results provide clear evidence suggesting that the PMd’s main thalamic targets (i.e., the nucleus reuniens and the AMv) seem to be critically involved in the emotional memory processing related to predator cues.     

Assessing the Validity of Data Synthesis Methods to Estimate Religious Populations

The present study tests the validity of a data synthesis approach to population estimates of religiously defined groups. This is particularly important in places like the United States, where there is no definitive source of official data on its population's religious composition, and researchers must rely on costly, large‐scale surveys, or congregational membership studies. Each approach has limitations, especially for estimation of small religious groups and for estimation within small geographic areas. Without official statistics, the degree of bias in estimates is unknown. Data synthesis, specifically Bayesian multilevel estimation with poststratification, offers a useful alternative that maximizes the utility of data across all sources to estimate multiple groups from the same sources of data. This method also facilitates comparison of groups. This study provides evidence of the validity of the approach by synthesizing data from Canada, a country that includes questions about religious identification in its national census.     

Social Support as a School Victimisation Risk Factor

This study examined three sources of social support, peer groups, school and parents, and their impact on the risk of relational, verbal and physical bullying victimization in a representative sample of secondary school adolescents of Talavera de la Reina (Spain). Correlation analysis was used to establish associations and regression analysis in order to confirm the independent effect of each social support type with victimization. The results showed that low social support perception from peers, school and parents increased the risk of relational, verbal and physical bullying victimization. Additionally, the perception of lower parental social support increased the likelihood of relational and verbal bullying victimization, while the hypothesis that low perception of parental social support entailed a higher risk for physical victimization was not confirmed. These findings are discussed in light of previous studies.     

Enabling Action: Reflections upon Inclusive Participatory Research on Health with Women with Disabilities in the Philippines

People with disabilities experience health disparities arising from social, environmental, and system-level factors. Evidence from a range of settings suggests women with disabilities have reduced access to health information and experience barriers to screening, prevention, and care services. This results in greater unmet health needs, particularly in relation to sexual and reproductive health. Women with disabilities are also more likely to experience physical and sexual violence than women without disabilities, further undermining their health. Community-based participatory research (CBPR) can generate knowledge and underpin action to address such health disparities and promote health equity. However, the potential and challenges of disability inclusion in CBPR, particularly in contexts of poverty and structural inequality such as those found in low- and middle-income countries, are not well documented. In this paper, we reflect on our experience of implementing and evaluating W-DARE, a three-year program of disability-inclusive CBPR aiming to increase access to sexual and reproductive health and violence-response services for women with disabilities in the Philippines. We discuss strategies for increasing disability inclusion in research and use a framework of reflexive solidarity to consider the uneven distribution of the benefits, costs, and responsibilities for action arising from the W-DARE program.     

Perspectives on Marital Love and Satisfaction in Mexican American and Anglo-American Couples

Aspects of intimacy and satisfaction were explored for a volunteer sample of 54 Mexican American (classified as either Hispanic-oriented or bicultural) and 30 Anglo-American married couples. Data were collected by questionnaire through network sampling. Measures included the Acculturation Rating Scale for Mexican Americans, a background inventory, the Love Attitudes Scale, and the Dyadic Adjustment Scale. Ethnic differences occurred for 3 love attitudes and 2 sex attitudes (e.g. Hispanic-oriented respondents were more pragmatic about love and less idealistic about sex). Passionate love was correlated with marital satisfaction for Anglo-Americans and both groups of Mexican Americans. Partner similarity was evident in all 3 groups, and marital satisfaction was best predicted for all groups by passionate love scores. Implications for counseling are discussed.