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111.
Research indicates that apoliprotein E (ApoE) plays a role in the development of Alzheimer's disease (AD) and possibly in the cognitive decline associated with normative aging. More recently, researchers have shown that ApoE is expressed in olfactory brain structures, and a relationship among ApoE, AD, and olfactory function has been proposed. In the current analyses, we investigated the contribution of ApoE and odor identification in decline trajectories associated with normative cognitive aging in various domains, using longitudinal data on cognitive performance available from the Swedish Adoption/Twin Study of Aging. Data on both ApoE status and olfactory functioning were available from 455 individuals ranging in age from 50 to 88 years at the first measurement occasion. Odor identification was measured via a mailed survey. Cognitive performance was assessed in up to 5 waves of in-person testing covering a period of 16 years. Latent growth curve analyses incorporating odor identification and ApoE status indicated a main effect of odor identification on the performance level in three cognitive domains: verbal, memory, and speed. A main effect of ApoE on rates of decline after age 65 was found for verbal, spatial, and speed factors. The consistency of results across cognitive domains provides support for theories that posit central nervous system-wide origins of the olfaction-cognition-ApoE relationship; however, olfactory errors and APOE ε4 show unique and differential effects on cognitive trajectory features. 相似文献
112.
Torre K Balasubramaniam R Rheaume N Lemoine L Zelaznik HN 《Psychonomic bulletin & review》2011,18(2):339-346
1/f (β) noise represents a specific form of (long-range) correlations in a time series that is pervasive across many sensorimotor variables. Recent studies have shown that the precise properties of the correlations demonstrated by a group of test participants may vary as a function of experimental conditions or factors characterizing the group. Our purpose in the present study was to clarify whether long-range correlations affect sensorimotor performance generally or in a task-specific manner and whether each individual produces characteristic long-range correlations that are reliable across several runs of the same task. We analyzed the series of time intervals produced by 43 participants in two timing tasks: unimanual rhythmic tapping and circle drawing. We found that a participant's 1/f (β) properties in tapping were not related to the 1/f (β) properties in circle drawing. However, within each task, individual differences were reliable, and a Cronbach's alpha of .59 showed a high degree of within-subjects reproducibility of the long-range correlations. Thus, long-range correlations represent a consistent and distinctive characteristic of individuals performing a particular task, rather than a ubiquitous generic property of sensorimotor time series. The implications of these results are discussed from both a theoretical and a methodological perspective. 相似文献
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Kangas A Zieber N Hayden A Quinn PC Bhatt RS 《Attention, perception & psychophysics》2011,73(8):2657-2667
Learning can be highly adaptive if associations learned in one context are generalized to novel contexts. We examined the development of such generalization in infancy in the context of grouping. In Experiment 1, 3- to 4-month-olds and 6- to 7-month-olds were habituated to shapes grouped via the organizational principle of common region and were tested with familiar and novel pairs as determined by the principle of proximity. Older infants generalized from common region to proximity, but younger infants did not. Younger infants failed to generalize when the task was easier (Experiment 2), and their failure was not due to inability to group via proximity (Experiment 3). However, in Experiment 4, even younger infants generalized grouping on the basis of connectedness to proximity. Thus, the ability to transfer learned associations of shapes to novel contexts is evident early in life, although it continues to undergo quantitative change during infancy. Moreover, the operation of this generalization mechanism may be induced by means of bootstrapping onto functional organizational principles, which is consistent with a developmental framework in which core processes scaffold learning. 相似文献
114.
Studenka BE Zelaznik HN Balasubramaniam R 《Quarterly journal of experimental psychology (2006)》2012,65(6):1086-1100
An internal clock-like process has been implicated in the control of rhythmic movements performed for short (250-2,000 ms) time scales. However, in the past decade, it has been claimed that a clock-like central timing mechanism is not required for smooth cyclical movements. The distinguishing characteristic delineating clock-like (event) from non-clock-like (emergent) timing is thought to be the kinematic differences between tapping (discrete-like) and circle drawing (smooth). In the archetypal event-timed task (tapping), presence of perceptual events is confounded with the discrete kinematics of movement (table contact). Recently, it has been suggested that discrete perceptual events help participants synchronize with a metronome. However, whether discrete tactile events directly elicit event timing has yet to be determined. In the present study, we examined whether a tactile event inserted into the circle drawing timing task could elicit event timing in a self-paced (continuation) timing task. For a majority of participants, inserting an event into the circle drawing task elicited timing behaviour consistent with the idea that an internal timekeeper was employed (a correlation of circle drawing with tapping). Additionally, some participants exhibited characteristics of event timing in the typically emergently timed circle drawing task. We conclude that the use of event timing can be influenced by the insertion of perceptual events, and it also exhibits persistence over time and over tasks within certain individuals. 相似文献
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Journal of Indian Council of Philosophical Research - 相似文献
118.
Zachary C. Irving Aaron Glasser Alison Gopnik Verity Pinter Chandra Sripada 《Cognitive Science》2020,44(10):e12908
Although mind-wandering research is rapidly progressing, stark disagreements are emerging about what the term “mind-wandering” means. Four prominent views define mind-wandering as (a) task-unrelated thought, (b) stimulus-independent thought, (c) unintentional thought, or (d) dynamically unguided thought. Although theorists claim to capture the ordinary understanding of mind-wandering, no systematic studies have assessed these claims. Two large factorial studies present participants (N = 545) with vignettes that describe someone's thoughts and ask whether her mind was wandering, while systematically manipulating features relevant to the four major accounts of mind-wandering. Dynamics explains between four and 40 times more variance in participants' mind-wandering judgments than other features. Our third study (N = 153) tests and supports a unique prediction of the dynamic framework—obsessive rumination contrasts with mind-wandering. Our final study (N = 277) used vignettes that resemble mind-wandering experiments. Dynamics had significant and large effects, while task-unrelatedness was nonsignificant. These results strongly suggest that the central feature of mind-wandering is its dynamics. 相似文献
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