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131.
João Quevedo Mônica Vianna Doriana Daroit Antônio G. Born Carlos R. Kuyven Rafael Roesler Jorge A. Quillfeldt 《Neurobiology of learning and memory》1998,69(3):320-325
Wistar rats with cannulae bilaterally implanted in the CA1 region of the dorsal hippocampus were trained in a step-down inhibitory avoidance task. Through these cannulae they received an infusion of 28 or 280 ng per side of the L-type voltage-dependent calcium channel antagonist nifedipine, or of its vehicle (20% dimethyl sulfoxide in saline). The two doses of the drug were studied by administration 0 or 30 min after training; in addition, the higher dose was studied by infusion 10 min before training. A retention test was carried out 24 h after the training session. The highest dose of nifedipine administered 0 min post-training enhanced test session performance of the animals compared to the control group; the effect of the lower dose was not statistically significant. There was no effect of the drug given 30 min post-training or 10 min pretraining. Despite the inability to discriminate direct neural from indirect vascular effects, these results are consistent with previous reports on nootropic actions of the dihydropyridine class of calcium channel blockers. The data are at variance with the amnestic effect of intrahippocampal nifedipine described by Lee and Lin (1991,Life Sciences,48,1333–1340), which may be attibuted to the different range of doses studied here. This might resemble the inverted U-shaped dose–response curve observed with another dihydropyridine, nimodipine, by other authors. 相似文献
132.
The Psychological Record - According to Epstein (1985), extinction is one of the main processes for creative problem solving. To test this assertion, we present an experiment in which we... 相似文献
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134.
Psychometric Properties of the Objectified Body Consciousness Scale (OBCS) in Spanish Preadolescents
Sicilia Alvaro Alcaraz-Ibáñez Manuel Granero-Gallegos Antonio Lirola María-Jesús Burgueño Rafael 《Sex roles》2020,82(3-4):241-251
Sex Roles - Objectification theory postulates that the body is constructed as a sexual object and is subject to observation and evaluation in such a way that a person may feel that their body is an... 相似文献
135.
Identifying protective factors present at schools located in neighborhoods with high structural violence is fundamental to help prevent the perpetuation of violence . Therefore, the aim of this study was to observe how some school micro‐system variables, such as school environment and interpersonal relationships that adults establish with adolescents, may lead to bullying behaviors or, on the contrary, to positive bystander behavior in the bully‐victim dynamic. The sample was composed of 5,774 adolescents from 71 schools located in violent neighborhoods in Lima (Peru). 31.9 per cent of the sample experienced verbal violence and the prevalence of cyberbullying was 24.6%. Boys were more prone to experience both types of bullying than girls, although no differences were seen in the probability of becoming aggressors during early and late adolescence. The protective model showed that a positive atmosphere based on a supportive environment with clear rules encouraged adults at school to show more support and to provide more orientation in bullying situations, thus promoting a positive bystander behavior between peers. Opposite results were observed in the risk model. Actions at the micro‐system school level are discussed to enhance protective factors and reduce risk factors. 相似文献
136.
Rafael de Almeida Oliveira Luciane Aparecida Pascucci Sande de Souza 《Journal of motor behavior》2017,49(3):235-243
The process by which the brain controls single-joint movements (SJM) is still not well understood. Some studies have defined rules describing the duration and magnitude of the agonist and antagonist muscles. Therefore, the purpose of this study was to analyze scientific publications about the electromyographic characteristics of SJM performed by patients with Parkinson's disease. A bibliographical review of the years 1989–2015 was performed using keywords such as electromyography, upper limb, and Parkinson's disease. After applying the inclusion criteria, 8 articles were included for analysis. The literature indicates that despite the lack of studies, it is possible to assume that considering the SJM, those with Parkinson's disease only control the magnitude of electromyography activation, being consistent only with the pulse-height theory control. 相似文献
137.
Helena García-Llana Maria-Auxiliadora Bajo Javier Barbero Rafael Selgas Gloria Del Peso 《Psychology, health & medicine》2017,22(4):474-482
Healthcare professionals currently working in Advanced Chronic Kidney Disease (ACKD) units must cope with difficult situations regarding assisting patients with the dialysis decision-making process, and they are often untrained for these conversations. Although we have evidence from the literature that these skills can be learned, few professionals feel confident in this area. A Communication and Bioethical Training (CoBiT) Program for ACKD staff (physicians, nurses and allied health professionals) was developed to improve their ability and self-confidence in conducting these conversations. A four-stage study was conducted: (1) development of the CoBiT program, beginning with the creation of an interdisciplinary focus group (N = 10); (2) design of a questionnaire to assess self-confidence based on the areas identified by the focus group. The face validity of the instrument was tested using an inter-judge methodology (N = 6); (3) design of the format and contents of the program; (4) piloting the program. Thirty-six health professionals took an 8-h workshop based on role-playing methodology. Participants assessed their self-confidence in their communication skills before and after the program using self-report measures. The results show that after the program, participants reported significantly higher levels of self-confidence measured with a five-point Likert scale (p < 0.001). Participants felt that communication with colleagues of other professions significantly increased after the workshop (p = 0.004). The CoBiT program improves ACKD Unit healthcare professionals’ self-confidence in their ability to perform a specific communication task. 相似文献
138.
Calderón-Garcidueñas L Mora-Tiscareño A Ontiveros E Gómez-Garza G Barragán-Mejía G Broadway J Chapman S Valencia-Salazar G Jewells V Maronpot RR Henríquez-Roldán C Pérez-Guillé B Torres-Jardón R Herrit L Brooks D Osnaya-Brizuela N Monroy ME González-Maciel A Reynoso-Robles R Villarreal-Calderon R Solt AC Engle RW 《Brain and cognition》2008,68(2):117-127
Exposure to air pollution is associated with neuroinflammation in healthy children and dogs in Mexico City. Comparative studies were carried out in healthy children and young dogs similarly exposed to ambient pollution in Mexico City. Children from Mexico City (n: 55) and a low polluted city (n:18) underwent psychometric testing and brain magnetic resonance imaging MRI. Seven healthy young dogs with similar exposure to Mexico City air pollution had brain MRI, measurement of mRNA abundance of two inflammatory genes cyclooxygenase-2, and interleukin 1 beta in target brain areas, and histopathological evaluation of brain tissue. Children with no known risk factors for neurological or cognitive disorders residing in a polluted urban environment exhibited significant deficits in a combination of fluid and crystallized cognition tasks. Fifty-six percent of Mexico City children tested showed prefrontal white matter hyperintense lesions and similar lesions were observed in dogs (57%). Exposed dogs had frontal lesions with vascular subcortical pathology associated with neuroinflammation, enlarged Virchow-Robin spaces, gliosis, and ultrafine particulate matter deposition. Based on the MRI findings, the prefrontal cortex was a target anatomical region in Mexico City children and its damage could have contributed to their cognitive dysfunction. The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children. 相似文献
139.
Harris RS 《The American psychologist》2008,63(4):275-6; discussion 277-9
140.