Behavioral engineering: the use of response priming to improve prescribed self-medication

A major problem in outpatient treatment has been the extreme irregularity with which patients use medication prescribed for them. As a new approach to resolving this problem, a portable operant apparatus was developed based on response priming and escape reinforcement. The apparatus sounded a tone at the time that a pill was to be taken. When the user turned a knob to terminate the tone, the apparatus delivered the pill into the user's hand. The apparatus was evaluated with six normal adults using a medically inert pill. A greater proportion of the pills were taken by each subject when using the special apparatus as compared with the use of a portable alarm timer or the usual wristwatch. These results demonstrate a new approach for increasing the regularity of self-administration of medicines.     

The differential optomotor response of the four-eyed fish Anableps anableps.

The perception of motion is important for the survival and reproduction of many animals, including fish. In the laboratory, support for this idea comes from the observation that many fish show a tendency to follow a series of stripes revolving around a circular aquarium. This response, known as the optomotor response (OMR), is recognized as an innate behavior in many species. The 'four-eyed' fishes of the genus Anableps are an unusual fish from Central and South America and actually have only two eyes. Each eye is divided into upper and lower halves internally and externally. This peculiar dual visual system allows Anableps to feed on creatures that swim or land near or on the water surface or to flee from flying predators attacking from above. It was hypothesized that Anableps should also possess the OMR. We used the OMR as a test to investigate potential differential visual processing in Anableps on normal and 'blinded' fish (the eyes are actually covered--not physically blinded). It was found that the OMR does exist in Anableps and that the strength of this response is dependent on the visual field being tested--a stronger OMR was seen as a result of visual stimulation from the aerial environment.