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21.
Laura A. Rabin Nadia Paré Andrew J. Saykin Michael J. Brown Heather A. Wishart Laura A. Flashman 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2013,20(3):357-376
ABSTRACT Episodic memory is the first and most severely affected cognitive domain in Alzheimer's disease (AD), and it is also the key early marker in prodromal stages including amnestic mild cognitive impairment (MCI). The relative ability of memory tests to discriminate between MCI and normal aging has not been well characterized. We compared the classification value of widely used verbal memory tests in distinguishing healthy older adults (n = 51) from those with MCI (n = 38). Univariate logistic regression indicated that the total learning score from the California Verbal Learning Test-II (CVLT-II) ranked highest in terms of distinguishing MCI from normal aging (sensitivity = 90.2; specificity = 84.2). Inclusion of the delayed recall condition of a story memory task (i.e., WMS-III Logical Memory, Story A) enhanced the overall accuracy of classification (sensitivity = 92.2; specificity = 94.7). Combining Logical Memory recognition and CVLT-II long delay best predicted progression from MCI to AD over a 4-year period (accurate classification = 87.5%). Learning across multiple trials may provide the most sensitive index for initial diagnosis of MCI, but inclusion of additional variables may enhance overall accuracy and may represent the optimal strategy for identifying individuals most likely to progress to dementia. 相似文献
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Shraga Serok Claire Rabin Yehudith Spitz 《International journal of group psychotherapy》2013,63(3):431-450
AbstractTeaching group therapy is an essential aspect of graduate studies within the helping professions. Existing models discuss four basic elements required for such training: experience, observation, supervised practice, and theory. The present paper offers a model for a group therapy seminar based on these four elements and organized along developmental concepts. Clinical observations of 120 psychology students who participated in the seminar were gathered over a five-year period. Teaching techniques included supervised observation, fish-bowl, one-way mirror, and a final paper integrating theory and practice. The seminar enabled students to practice and to theorize about group processes, both as participants and as co-leaders. Seminar outcomes and conclusions are discussed. 相似文献
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Lissek S Biggs AL Rabin SJ Cornwell BR Alvarez RP Pine DS Grillon C 《Behaviour research and therapy》2008,46(5):678-687
Though generalization of conditioned fear has been implicated as a central feature of pathological anxiety, surprisingly little is known about the psychobiology of this learning phenomenon in humans. Whereas animal work has frequently applied methods to examine generalization gradients to study the gradual weakening of the conditioned-fear response as the test stimulus increasingly differs from the conditioned stimulus (CS), to our knowledge no psychobiological studies of such gradients have been conducted in humans over the last 40 years. The current effort validates an updated generalization paradigm incorporating more recent methods for the objective measurement of anxiety (fear-potentiated startle). The paradigm employs 10, quasi-randomly presented, rings of gradually increasing size with extremes serving as CS+ and CS−. The eight rings of intermediary size serve as generalization stimuli (GSs) and create a continuum-of-similarity from CS+ to CS−. Both startle data and online self-report ratings demonstrate continuous decreases in generalization as the presented stimulus becomes less similar to the CS+. The current paradigm represents an updated and efficacious tool with which to study fear generalization—a central, yet understudied conditioning-correlate of pathologic anxiety. 相似文献
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Lillian Huang Cummins Erin C. Dunn Leora Rabin Joan Russo Katherine Anne Comtois Barbara S. McCann 《Journal of clinical psychology in medical settings》2003,10(1):51-56
Current guidelines for the evaluation and treatment of obesity recommend referring individuals with binge eating disorder (BED) to a mental health professional. However, it is unclear how familiar primary care providers are with BED. The purpose of this study was to assess providers' familiarity with BED diagnosis and treatment. Providers in two primary care clinics completed a questionnaire, which assessed perceived familiarity with BED and demonstrated familiarity with BED diagnosis and treatment. Results indicated that 61% of respondents demonstrated familiarity with the essential symptoms of BED, and 80% reported familiarity with the diagnosis of BED. However, 35% of respondents who perceived themselves as familiar with BED did not demonstrate familiarity with the most basic symptoms. These results demonstrate that while many providers in primary care are familiar with BED, steps to improve provider familiarity with the disorder and provide appropriate mechanisms to address BED are warranted. 相似文献
25.
Sheldon Cohen Jay R Kaplan Joan E Cunnick Stephen B Manuck Bruce S Rabin 《Psychological science》1992,3(5):301-304
Abstract ——We report the first experimental study of the effect of long–term (over 2 years) exposure to a stressor on cellular immune response Forty–three male cynomolgus monkeys were randomly assigned to stable or unstable social conditions for 26 months The proportion of time spent in affiliative behaviors was assessed by observations made twice weekly T–cell immune response (mitogen–stimulated cell proliferation) was assessed weekly for 3 weeks immediately following the 26–month manipulation The possibility that affiliative behavior represents an attempt to cope with social stress was supported by greater affiliation among animals m the unstable condition than in the stable condition Animals in the unstable condition also demonstrated relatively suppressed immune response More affiliative animals showed enhanced immune response, with the beneficial effects of affiliation occurring primarily among unstable animals The data are interpreted as consistent with the stress–buffering hypothesis, that IS, affiliation protects animals from the potentially pathogenic influences of chronic social stress 相似文献
26.
Rina Erez Stanley Rabin Louis Shenkman Eliezer Kitai 《Journal of religion and health》1999,38(1):67-72
The ultraorthodox Jewish community of Kfar Habbad Village is a special minority community in the Israeli context, one with particular needs because of its special religious and social commitments. This paper gives a personal account of a family physician's work in treating this population. It emphasizes the unique role of the doctor in her ongoing interaction with the rabbis of the Village and the doctor's use of community resources in order to meet the special needs of the group. 相似文献
27.
Brain activation patterns differ and generation latencies are reduced when generating verbs to repeated nouns (Raichle et al., 1994). Amnesic participants show normal magnitude of priming (Seger et al., 1997). Despite its importance in neuropsychology, verb generation priming is not well characterized psychologically. Six behavioral studies found that verb generation priming was specific to the verb rather than to the noun or the noun-verb pair, was equivalent after overt or covert generation and after reading verbs or generating verbs, was affected by levels of processing, and transferred completely across languages in bilinguals. These results indicate that verb generation priming involves priming of particular responses and happens at a conceptual level. These findings provide new insights about the significance of brain imaging and neuropsychological studies involving verb generation priming. 相似文献
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Assessing motivation for parenthood 总被引:1,自引:0,他引:1
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Although copper sulfate is an emetic stimulus, preliminary experiments failed to obtain a taste aversion in intact rats following intragastric administration as had been previously reported in the literature. Several experiments were therefore run to further investigate the capacity of intragastric copper sulfate to function as an unconditioned stimulus for taste aversion learning and the role of the vagus in mediating that learning. The results of the first series of experiments showed that intragastric administration of copper sulfate (5 mg/kg X 5H2O) was more effective in reliably producing a taste aversion in vagotomized rats than in sham-operated control rats. The second experiment examined the effects of area postrema lesions on the acquisition of a taste aversion produced by intragastrically administered copper sulfate in vagotomized rats. The results indicated that the taste aversion observed following treatment with intragastric copper sulfate in vagotomized rats could be prevented by lesions of the area postrema. The present results indicate that intragastric administration of copper sulfate is a more reliable unconditioned stimulus for taste aversion learning in vagotomized rats than in intact rats. It is not certain what factors might account for the discrepant results between the present experiments and previously published research. 相似文献