Bidimensional regression: assessing the configural similarity and accuracy of cognitive maps and other two-dimensional data sets

Bidimensional regression is a method for comparing the degree of resemblance between 2 planar configurations of points and, more generally, for assessing the nature of the geometry (Euclidean and non-Euclidean) between 2-dimensional independent and dependent variables. For example, it can assess the similarity between location estimates from different tasks or participant groups, measure the fidelity between cognitive maps and actual locations, and provide parameters for psychological process models. The authors detail the formal similarity between uni- and bidimensional regression, provide computational methods and a new index of spatial distortion, outline the advantages of bidimensional regression over other techniques, and provide guidelines for its use. The authors conclude by describing substantive areas in psychology for which the method would be appropriate and uniquely illuminating.     

Global-scale location and distance estimates: common representations and strategies in absolute and relative judgments

The authors examined whether absolute and relative judgments about global-scale locations and distances were generated from common representations. At the end of a 10-week class on the regional geography of the United States, participants estimated the latitudes of 16 North American cities and all possible pairwise distances between them. Although participants were relative experts, their latitude estimates revealed the presence of psychologically based regions with large gaps between them and a tendency to stretch North America southward toward the equator. The distance estimates revealed the same properties in the representation recovered via multidimensional scaling. Though the aggregated within- and between-regions distance estimates were fitted by Stevens's law (S. S. Stevens, 1957), this was an averaging artifact: The appropriateness of a power function to describe distance estimates depended on the regional membership of the cities. The authors conclude that plausible reasoning strategies, combined with regionalized representations and beliefs about the location of these relative to global landmarks, underlie global-scale latitude and distance judgments.     

The ethical limits in expanding living donor transplantation

The past decade has witnessed the emergence of novel methods to increase the number of living donors. Although such programs are not likely to yield high volumes of organs, some transplant centers have gone to great lengths to establish one or more of them. I discuss some of the ethical and policy issues raised by five such programs: (1) living-paired and cascade exchanges; (2) unbalanced living-paired exchanges; (3) list-paired exchanges; (4) nondirected donors; and (5) nondirected donors catalyzing cascade exchanges. I argue that living-paired and cascade exchanges are ethically sound, but will lead to only a few additional transplants. Unbalanced exchanges and list-paired exchanges raise ethical issues that should limit their permissibility. Nondirected donations can be ethically sound with adherence to strict eligibility criteria and fair allocation procedures. Nondirected donors catalyzing cascade exchanges can be ethically sound provided that individuals with blood types O and B are not made worse off.     

Flirting with virtual reality

Psychoanalysis encourages patients to experience a virtual reality of the psychoanalytic relationship, in which both image and wish can be experimented with. Originally, the patient's awareness was supposed to move back and forth between the virtual and the actual, in a flickering and uncertain fashion. That is uncomfortable, and analysts have often preferred the domain of virtuality or of actuality, or have denied the distinction altogether. Recent philosophical developments and doubts about transference neurosis and reconstruction further tempt analysts to relax the flickering uncertainty of virtual and actual. Patient and analyst may gain comfort but lose something in the process.     

Impaired oral reading in two atypical dyslexics: a comparison with a computational lexical-analogy model

A computational model of reading was developed based upon the notion that the structural relationship between orthography and phonology is of greater importance than the dimension of semantics for the reading aloud of single words. Degradation of this model successfully simulated the reading performance of two patients with atypical acquired dyslexia. The first patient CAV, studied and described in the literature by Warrington in 1981, presented with unusual concrete word dyslexia, i.e., he had a category-specific reading deficit for concrete words compared with abstract words. The second patient BG is a phonological dyslexic who, although displaying a strong concreteness effect (concrete words read better than abstract words), was able to read functors individually perfectly well, a pattern that is rarely if ever seen. The computational model was used to generate a set of words for which it was predicted that BG would show no concreteness effect. The results of BG's reading of these words were consistent with this prediction, thereby providing greater support for the validity of the model. It is concluded that a computational approach that attempts not only to reproduce the core symptoms of the major varieties of acquired dyslexia but also to simulate clinical data from specific patients has much to contribute to the understanding of cognitive deficits and to the design of effective rehabilitation strategies.     

Forgetting all else: on the antecedents and consequences of goal shielding

Six studies explore the role of goal shielding in self-regulation by examining how the activation of focal goals to which the individual is committed inhibits the accessibility of alternative goals. Consistent evidence was found for such goal shielding, and a number of its moderators were identified: Individuals' level of commitment to the focal goal, their degree of anxiety and depression, their need for cognitive closure, and differences in their goal-related tenacity. Moreover, inhibition of alternative goals was found to be more pronounced when they serve the same overarching purpose as the focal goal, but lessened when the alternative goals facilitate focal goal attainment. Finally, goal shielding was shown to have beneficial consequences for goal pursuit and attainment.     

Predictive genetic testing for conditions that present in childhood

There is a general consensus in the medical and medical ethics communities against predictive genetic testing of children for late onset conditions, but minimal consideration is given to predictive testing of asymptomatic children for disorders that present later in childhood when presymptomatic treatment cannot influence the course of the disease. In this paper, I examine the question of whether it is ethical to perform predictive testing and screening of newborns and young children for conditions that present later in childhood. I consider the risks and benefits of (1) predictive testing of children from high-risk families; (2) predictive population screening for conditions that are untreatable; and (3) predictive population screening for conditions in which the efficacy of presymptomatic treatment is equivocal. I conclude in favor of parental discretion for predictive genetic testing, but against state-sponsored predictive screening for conditions that do not fulfill public health screening criteria.     

Spatial location judgments: a cross-national comparison of estimation bias in subjective North American geography

We examined alternate explanations for distortions in the subjective representation of North American geography. One explanation, based on physical proximity, predicts that bias in location estimates should increase with the distance from a participant's home city or region. An alternative is that biases arise from combining accurate and inaccurate beliefs about the cities and the superordinate regions to which they belong, including beliefs that may have social or cultural origins. To distinguish these, Canadians from Alberta and Americans from Texas judged the latitudes of cities in Canada, the U.S., and Mexico. The Texans' estimates of Mexican locations were 16" (approximately 1,120 miles) more biased than their estimates of Canadian locations that were actually about 840 miles farther away. This finding eliminates proximity as a primary source of geographic biases and underscores the role of categorical beliefs as an important source of biased judgments.     

The impact of conflict of interest on trust in science

Conflicts of interest have an erosive effect on trust in science, damaging first the attitude of the public toward scientists and their research, but also weakening the trusting interdependence of scientists. Disclosure is recognized as the key tool for management of conflicts, but rules with sanctions must be improved, new techniques for avoidance of financial conflicts by alternative funding of evaluative research must be sought, and there must be new thinking about institutional conflicts of interest. Our profession is education, and both the public and research professionals of all ages would benefit from greater understanding of how science should and does work. An earlier version of this paper was presented at an International Conference on “Conflict of Interest and its Significance in Science and Medicine” held in Warsaw, Poland on 5–6 April, 2002.