Behavioral profile of L‐655,708, a selective ligand for the benzodiazepine site of GABA‐A receptors which contain the α5 subunit,in social encounters between male mice

GABA‐A receptor is a transmembrane hetero‐oligomeric protein which consists of five subunits, the combination of which confers unique pharmacological properties to the receptor. It is well‐known that the GABAergic system is involved in the modulation of aggression. However, the role of α5/GABA‐A receptors has not been explored. In this study, we examined the effect of L‐655,708 (0.625‐5 mg/kg), a selective ligand for the benzodiazepine site of GABA‐A receptors which contain the α5 subunit, on agonistic behavior elicited by isolation in male mice. Individually housed mice were exposed to an anosmic “standard opponent” 30 min after drug administration, and the encounters were videotaped and evaluated using an ethologically based analysis. L‐655,708 (5 mg/kg) exhibited an ethopharmacological profile characterized by a marked reduction of the time spent in offensive behavior (threat and attack) without affecting immobility, accompanied by a significant increase of avoidance/flee and nonsocial exploration behaviors, suggesting that the antiaggressive effect of the drug is unselective. Overall, this behavioral profile might indicate the existence of an anxiogenic‐like activity of L‐655,708 in mice. Aggr. Behav. 30:319–325, 2004. © 2004 Wiley‐Liss, Inc.     

The influence of an early interview on long‐term recall: a comparative analysis

Because of burgeoning participation by children in forensic situations there is significant concern about children's memory for stressful events. Influence of timing of the first interview and interview frequency on long‐term recall were evaluated by comparing three groups of 3‐ to 9‐year‐olds 1 year after an injury requiring emergency room treatment. One group had one interview, a year after injury; another group had two interviews, immediately and a year later; the third group had three interviews, immediately, 6 months and a year after injury. The type of event and timing of the initial interview influenced completeness and accuracy of recall after 1 year. All children showed extensive recall but having an immediate interview was associated with greater completeness and accuracy for 3–4‐year‐olds but not older children. This suggests a social influence: a highly structured and organized early interview may have beneficial effects on memory for preschoolers. Implications for questioning and testimony are discussed. Copyright © 2004 John Wiley & Sons, Ltd.     

Politics and Prioritization of Evil

In this essay I question an assumption of Card's, which seems to place the (Kantian'style) ethical in a directive relationship with respect to the political. I call attention to the rupture between the two as a marker of modernity and suggest that the political is not only a sphere of power but also a value‐sedimented field, with the values in question developing historically as in the case of liberal democracy.     

De‐escalation after repeated negative feedback: emergent expectations of failure

Research on willingness to make marginal investments (e.g., the escalation and sunk cost literatures) has often focused on project completion decisions, such as the “radar‐blank plane.” This paper discusses a fundamentally different type of marginal investment decision, that of couples deciding whether to continue infertility treatment in the face of repeated failures. Two experiments based on this context show that when people face multiple independent chances to achieve a valued goal but are unsure about chances of success, premature quitting or “de‐escalation” is the norm. Repeated negative feedback appears to induce individuals to see each successive failure as more and more diagnostic. As a result, even a short series of failed attempts evokes beliefs that future attempts will also fail. These emergent expectations of failure, generated by causal attribution processes, associative learning, and/or discounting of ambiguous information, appear very compelling and induce people to forgo profitable marginal investments. Copyright © 2004 John Wiley & Sons, Ltd.     

How does preference reversal appear and disappear? Effects of the evaluation mode

Preference reversal is a systematic change in the preference order between options when different response methods are used (e.g., choice vs. judgment). The present study focuses on procedures used to elicit preferences according to an evaluability hypothesis. Two experiments compared joint vs. separate evaluations and explicit vs. non‐explicit joint evaluations. Subjects had to express preferences between high‐variance gambles (HVGs) and low‐variance gambles (LVGs) either by choosing one gamble to play in a lottery or by assigning gambles minimum selling prices. We show that HVGs are preferred in both choice and pricing conditions when gambles are evaluated separately, and LVGs are preferred in both choice and selling conditions when gambles are evaluated in pairs: i.e., when the evaluation mode is held constant, classic preference reversal disappears. These results support the evaluability hypothesis, and suggest that preferences depend on whether subjects are allowed to compare the options they are asked to choose from or judge, independently of the nature of the scale (i.e., attractiveness vs. minimum selling price) they are required to adopt. Copyright © 2004 John Wiley & Sons, Ltd.     

Choosing How to Choose: Institutional Pressures Affecting the Adoption of Personnel Selection Procedures

The gap between science and practice in personnel selection is an ongoing concern of human resource management. This paper takes Oliver's framework of organizations' strategic responses to institutional pressures as a basis for outlining the diverse economic and social demands that facilitate or inhibit the application of scientifically recommended selection procedures. Faced with a complex network of multiple requirements, practitioners make more diverse choices in response to any of these pressures than has previously been acknowledged in the scientific literature. Implications for the science‐practitioner gap are discussed.     

Maternal insightfulness and preschoolers' emotion and behavior problems: Reciprocal influences in a therapeutic preschool program

Mothers' insightfulness, which involves understanding the motives underlying the child's behavior in a complete, open, and accepting way, was examined both at the beginning and at the end of a therapeutic preschool program for preschoolers using the Insightfulness Assessment (Oppenheim & Koren‐Karie, 2002). The goal of the study was to examine the links between improvement in mothers' insightfulness and reduction in children's behavior problems. Thirty‐two children referred to a therapeutic preschool program for a range of behavioral and emotional problems and their mothers participated in the study. Results showed that mothers who shifted from noninsightfulness before treatment to insightfulness after treatment had children whose behavior problems decreased whereas mothers who did not make such gains had children whose behavior problems increased. The social skills of all children improved during treatment. The possible mechanisms linking the gains of mothers and children are discussed within the framework of attachment theory.     

AQS security scores: What do they represent? A study in construct validation

In a sample of 129 Dutch 15‐month‐old infants, attachment security was assessed both with the Attachment Q‐Set (AQS; Waters, 1995) and with a short version of Ainsworth, Blehar, Waters, and Wall's (1978) Strange Situation (SSS). Infants classified as secure using the SSS had significantly higher AQS scores than insecure and disorganized infants in particular. At the AQS item level, disorganized infants were described as significantly more noncompliant, fussy, and angry relative to secure infants. When security as assessed using the SSS was controlled, the observed quality of parental interactive behavior, parental ego‐resilience, high levels of infant task orientation and pleasure, and low levels of infant anger proneness were found to explain significant and unique portions of the variance in the AQS security scores. The apparently unfavorable set of characteristics associated with low AQS security scores suggests such scores to predict later developmental problems. ©2004 Michigan Association for Infant Mental Health.