Biomagnetism from the neuropsychiatric viewpoint--principles of recent developments in diagnostic procedure

The following survey is intended to demonstrate and discuss some principle problems of biomagnetism and the application in clinical fields. The development of special technical parameters especially by the SQUID method is initiating new possibilities of research and completing the neurobiologically determinated basis and conditions of neuropsychiatric disorders. The Magnetoencephalography (MEG) will be represent an important role of a new functional diagnostic method.     

Infant hypotonia, obesity, hypogenitalism and oligophrenia--new viewpoints on the etiology and symptoms of Prader-Willi syndrome

We present four cases of Prader-Willi syndrome. Two of them have an abnormality of a chromosome 15, the other both show different chromosomal abnormalities. Translocations or deletions were found recently in the bands 15q11/12 in about 60% of the cases of Prader-Willi syndrome. The consequences for diagnosis, symptomatology and genetic counselling of the syndrome are discussed.     

Organism-environment mutuality epistemics,and the concept of an ecological niche

The concept of an ecological niche (econiche) has been used in a variety of ways, some of which are incompatible with a relational or functional interpretation of the term. This essay seeks to standardize usage by limiting the concept to functional relations between organisms and their surroundings, and to revise the concept to include epistemic relations. For most organisms, epistemics are a vital aspect of their functional relationships to their surroundings and, hence, a major determinant of their econiche. Rejecting the traditional dualism of organism and environment, an econiche is defined as the reciprocal (dual) of a functionally specified class of organisms (FSTU). From this perspective, an econiche necessarily implies a certain type of organism, and a class of functionally similar organisms implies a special econiche.The econiche concept is also discussed in relation to other ecological terms that reflect the distributional patterns of organisms, such as habitat, and the concept of an empty niche is criticized.Special thanks are due to Michael Turvery for his part in many stimulating discussions of some of the problems and concepts addressed in this paper. I am also grateful to him and to Claudia Carello, Tim Johnston, Bill Mace, Bernard Patten, Ed Reed, Robert E. Shaw, Bill Warren, and an anonymous reviewer for their comments on earlier drafts of this paper.     

Social categorization,visual cues,and social judgements

Recent research on social cognition suggests that lifelike visual and vocal information about a person may strongly mediate the impact of prior social categorical knowledge on social judgements. Other research, however, on the contribution of visual cues to impression formation, suggests that they have relatively little impact. This study sought to resolve these conflicting findings by examining the effect of visual cues on social judgements when subjects possess prior social categorical knowledge varying in salience to the experimental task. Videotaped target interviews were monitored by observers in either sound and vision or sound only, and measures were taken of the targets' perceived personality, their ‘actual’ and ‘predicted’ social performance, and social acceptance by observers. Whilst salience of categorization strongly influenced the quality of judgements, visual cues had little if any effect. However, visual cues strongly influenced subjects' confidence in all three sets of judgements, sound and vision subjects being consistently more confident than their sound only counterparts. The findings are discussed in relation to previous research in both social cognition and visual cues.     

Surface form and the spacing effect

Deficient processing theories of the spacing effect attribute poor recall of massed-repeated items to a failure to process one or both of the presentations fully. An implication of this approach is that anything that increases the probability that a repetition will receive full processing, or conversely, anything that decreases the probability that the item will be recognized as a repetition, should improve memorability of the item. The present set of experiments tested this prediction by manipulating the surface structure of repeated sentences. On the basis of previous research, it was assumed that memory for surface structure of sentences decays rapidly, and hence can contribute to initial identification of repetitions only at short spacings. Because this manipulation should hinder recognition of repetitions as repetitions, it was expected to induce full processing of massed repetitions, and thus facilitate recall of these items. This prediction was supported. When sentences were repeated verbatim (Experiment 1) or by the same speaker (Experiment 2), the typical spacing effect was obtained. However, when the surface structure or speaker changed at time of repetition, massed repetitions were recalled nearly as well (Experiment 1) or as well (Experiment 2) as their spaced counterparts.     

Parents' teaching strategies with their children: The effects of parental and child status variables

The intent of the study was to examine the effects of parental (mother and father) and child (gender and communicative status) status variables on the teaching strategies used by parents in a paper-folding task. The linguistic and nonverbal strategies of 120 parent-child groupings were analyzed during paper-folding tasks. Parents' strategies were coded according cognitive demand and directiveness. Results indicated that strategies varied as a function of children's communicative status. Parents were less directive and more demanding of nonhandicapped children compared to handicapped children. Parents' strategies seemed to be determined by children's ability to sustain discourse. Results are discussed in terms of Vygotsky's notion of the zone of proximal development.This research was partially supported by a grant from the U.S. Office of Education, Office of Special Education (Grant No. G007902000) to I. Sigel and A. McGillicuddy-DeLisi at Educational Testing Service, Princeton, and from the Biomedical Research Support Grant Program, Division of Research Resources, N.I.H. (Grant No. BRSG 507RR07025-17) to the first two authors. We acknowledge the helpful comments of two anonymous reviewers.     

Continuous monitoring of human contingency judgment across trials

Recent evidence suggests that people are sensitive to the degree of contingency between their actions and ensuing outcomes, but little is known about the way in which such contingency judgments develop as more and more information about the contingency is provided. Three experiments examined this issue in the context of a video game. In Experiment 1, it was found that contingency judgments follow growth functions: When the contingency was positive, judgments increased toward a positive asymptote, and when the contingency was negative, judgments decreased toward a negative asymptote. When the contingency was zero, judgments themselves remained close to zero but were biased by the overall frequency with which the outcome occurred. In Experiment 2, it was shown that the growth function was not the result of the anchoring of early judgments at the zero point. The bias in judgments when the contingency is zero was investigated in Experiment 3. The results are discussed in terms of rule-based analyses and contemporary theories of conditioning.     

Differential ethanol olfactory experiences affect ethanol ingestion in preweanlings but not in older rats

Preweanling (21 days old) and adult (60-80 days old) rats were exposed to ethanol odor either paired with the early stages of apomorphine-induced toxicosis, paired with the recovery from toxicosis, or unpaired with the induction of distress. Twenty four hours later, ethanol preferences were measured in a spatial olfactory test (ethanol vs lemon odor) or a drinking test (5.6% v/v ethanol vs 0.25% w/v citric acid solutions). During the olfactory test both young and adult rats expressed substantial ethanol odor aversions when previously exposed to this odor paired with toxicosis. However, changes in ethanol intake became apparent only in preweanling subjects. Preweanlings which received the ethanol odor paired with illness drank significantly less of the ethanol solution relative to controls, while subjects experiencing the odor paired with recovery from distress significantly increased their consumption of the ethanol solution. These prior aversive and appetitive olfactory experiences had no effect upon ethanol intake in adult rats. These results implicate both an ontogenetic and a sensorial factor in the regulation of ethanol intake.