序列学习的ERP研究综述

对近些年国外序列学习的ERP研究进行了总结.序列学习研究选取的ERP成分主要包括N200、P300、CNV、LRP、ERN、MMN等;关注的问题主要集中在意识与序列学习的关系、序列学习的表征问题以及序列学习中一些相似ERP成分的差异等方面.     

论道义论与功利论的一个根本区分:正当与善何者优先

道义论与功利论是当代西方规范伦理学的两种基本理论形态.两者的区分可以以正当与善何者优先来界定.一般来说,强调正当优先于善,并不以善来界定正当的理论是道义论理论,而以善优先于正当,并以善来规定正当的理论是功利论理论.     

Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins

Purple sweet potato color (PSPC), a class of naturally occurring anthocyanins used to color food (E163), has been reported to possess a variety of biological activities, including anti-oxidant, anti-tumor, and anti-inflammatory. The effect of PSPC on the spatial learning and memory of mice treated with d-galactose (d-gal) was evaluated by the Morris water maze; d-gal-treated mice had decreased performance compared with mice in the vehicle and PSPC groups, while the PSPC + d-gal group showed significantly shortened escape latency to platform, increased swimming speed, more target quadrant search time and more platform crossings as compared with the d-gal group. Brain functions, such as memory formation and recovery of function after injury, depend on proper regulation of the expression levels of the pre- and post-synaptic proteins. We investigated the expression of four pre-synaptic proteins (growth-associated protein-43, synapsin-I, synaptophysin, and synaptotagmin) and two post-synaptic proteins (post-synaptic density protein-95 and Ca²⁺/calmodulin-dependent protein kinase II) in the hippocampus and cerebral cortex, respectively, in response to different treatments. Western blotting analysis showed that there were significant decreases in the expression of these representative synaptic proteins in the hippocampus and cerebral cortex of d-gal-treated mice. Interestingly, these decreased expression levels of synaptic proteins could be reversed by PSPC. The levels of expression of these representative synaptic proteins in mice treated with PSPC alone were not significantly different from those in untreated mice. The results of this study suggested that memory impairment and synaptic protein loss in d-gal-treated mice may be improved by treatment with PSPC.     

老年人生命态度及其与抑郁和社会支持的关系

使用死亡态度描绘量表(修订版)、流调中心用抑郁量表和个人资源量表2000对京津地区的516位老年人进行问卷调查,探讨老年人生命态度的结构及特点,并选取几个因素探讨其对老年人生命态度的影响。结果表明:(1)生命态度的结构包含死亡恐惧、死亡逃避、自然接受、趋近接受和逃离接受五个维度。(2)在生命态度的五个维度中,自然接受和趋近接受存在显著的性别差异,死亡恐惧、自然接受和逃离接受存在显著的教育程度差异;(3)抑郁与自然接受呈显著负相关,与生命态度其他四个维度呈显著正相关;社会支持与死亡恐惧呈显著负相关,与自然接受呈显著正相关。     

自我调控学习:研究背景、方法发展与未来展望

自我调控学习(self-regulated leaming,SRL)是学生学习成功的终极问题.本文重点考察了自我调控学习的第二次研究浪潮,即有关即时测量自我调控过程研究方法的发展,如利用电脑跟踪、有声思维口头报告法、学生学习的结构化日记和微观的周期模型分析法,利用这些自我调控法,能够体现自我调控干预培训的有效性.虽然这些即时事件测量的方法仍处于雏形发展阶段,但对于自我调控学习的因果推论提供了宝贵的信息资料.本文还对今后相关重点课题和研究方法指明了方向.     

原生家庭父母冲突、 夫妻冲突解决模式与婚姻质量的关系:基于主客体互倚模型的分析

采用问卷调查法,对263对夫妻的原生家庭父母冲突、 夫妻冲突解决模式和婚姻质量进行测量.结果表明,(1)个体的原生家庭父母冲突与自身以及配偶的婚姻质量呈显著负相关;(2)丈夫的原生家庭冲突可以预测自身以及妻子的冲突解决模式,妻子的原生家庭冲突可预测丈夫的冲突解决模式;(3)丈夫夫妻冲突解决模式在双方原生家庭父母冲突对自...     

缘起论对于佛教道德哲学的基础意义

此有生无灭即彼有生无灭的缘起论是佛教道德哲学的核心理论,体现了佛教伦理的关系性思维。佛教依此建立起道德哲学体系中四谛、八正道、十二因缘、四法印等基本原理,体现出无我、平等、慈悲、民主、超越等基本伦理精神,显示了佛教作为道德性宗教的特色。     

维吾尔族与汉族的大学生在汉语歧义词消解中的语境促进效应及反应抑制效应

词汇歧义是语言的普遍现象。在汉语中, 歧义词的种类繁多, 是少数民族学生汉语学习困难的重要原因之一。通过两个实验, 考察在不同加工时间条件下维吾尔族和汉族的大学生在汉语歧义词消解中的语境促进效应及抑制效应。结果发现, 两个民族的大学生均出现了语境促进效应, 但在短时加工条件下, 汉族大学生的语境促进效应显著大于维吾尔族大学生, 在长时加工条件下, 两个民族的大学生的语境促进效应并无显著差异。在短时加工条件下, 仅汉族大学生可以有效地抑制无关信息的干扰; 在长时加工条件下, 两个民族的大学生均可以有效地抑制无关信息的干扰。整个研究表明, 在汉语歧义词消解中, 随着加工时间增加, 维吾尔族大学生的语境促进效应和对无关信息的抑制均可以达到与汉族大学生相近的水平。     

催产素对学习和记忆的调节效应：来自动物与人类的研究证据

作为一种神经肽, 催产素对于个体社会认知和情绪加工有着非常重要的调节作用, 其中就包括对在人们工作和生活中扮演着关键角色的学习和记忆活动的影响。采用不同模态技术的动物和人类研究一致表明了外源性催产素对于学习和记忆具有重要的调节作用, 这一作用可能是外源性催产素通过与多巴胺奖赏通路、边缘系统等学习和记忆关键脑网络中广泛分布的催产素受体相结合, 进而调整其功能状态实现的; 但与此同时, 催产素对学习和记忆的促进或抑制作用会因实验范式、刺激材料、给药时间、位置和剂量等因素的不同而存在差异。未来需要协同动物和人类研究的各自优势, 采用规范化的实验任务设置和给药程序克服当前该领域的研究局限, 并积极发掘催产素在干预相关精神疾病患者学习和记忆加工缺陷中的应用潜力。     

Cognitive control in belief‐laden reasoning during conclusion processing: An ERP study

Belief bias is the tendency to accept conclusions that are compatible with existing beliefs more frequently than those that contradict beliefs. It is one of the most replicated behavioral findings in the reasoning literature. Recently, neuroimaging studies using functional magnetic resonance imaging (fMRI) and event‐related potentials (ERPs) have provided a new perspective and have demonstrated neural correlates of belief bias that have been viewed as supportive of dual‐process theories of belief bias. However, fMRI studies have tended to focus on conclusion processing, while ERPs studies have been concerned with the processing of premises. In the present research, the electrophysiological correlates of cognitive control were studied among 12 subjects using high‐density ERPs. The analysis was focused on the conclusion presentation phase and was limited to normatively sanctioned responses to valid–believable and valid–unbelievable problems. Results showed that when participants gave normatively sanctioned responses to problems where belief and logic conflicted, a more positive ERP deflection was elicited than for normatively sanctioned responses to nonconflict problems. This was observed from ?400 to ?200 ms prior to the correct response being given. The positive component is argued to be analogous to the late positive component (LPC) involved in cognitive control processes. This is consistent with the inhibition of empirically anomalous information when conclusions are unbelievable. These data are important in elucidating the neural correlates of belief bias by providing evidence for electrophysiological correlates of conflict resolution during conclusion processing. Moreover, they are supportive of dual‐process theories of belief bias that propose conflict detection and resolution processes as central to the explanation of belief bias.