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161.
162.
Recent models of alcohol use in youth and young adulthood have incorporated personality change and maturation as causal factors underlying variability in developmental changes in heavy drinking. Whereas these models assume that personality affects alcohol use, the current prospective study tested the converse relation. That is, we tested whether, after accounting for the effect of traits on drinking, collegiate heavy drinking in turn predicted individual differences in change in alcohol-related aspects of personality. We also examined whether affiliation with heavy-drinking peers better accounted for this relation. Following a cohort of recent high school graduates (N=1,434) through the college years, we found evidence for transactional relations between heavy drinking and changes in impulsivity and sensation seeking. Both traits predicted increases in heavy drinking, but more important, heavy drinking predicted increases in sensation seeking and impulsivity. In final models, social influences did not underlie the effect of heavy drinking on increases in sensation seeking and impulsivity. The results of this investigation suggest that collegiate heavy drinking may negatively and pervasively impact a wide range of behaviors because of its effect on personality change.  相似文献   
163.
Little is known about how APOE ε4-related differences in cognitive performance translate to real-life performance, where training and experience may help to sustain performance. We investigated the influences of APOE ε4 status, expertise (FAA pilot proficiency ratings), and their interaction on longitudinal flight simulator performance. Over a 2-year period, 139 pilots aged 42-69 years were tested annually. APOE ε4 carriers had lower memory performance than noncarriers (p = .019). APOE interacted with Expertise (p = .036), such that the beneficial influence of expertise (p = .013) on longitudinal flight simulator performance was more pronounced for ε4 carriers. Results suggest that relevant training and activity may help sustain middle-aged and older adults' real-world performance, especially among APOE ε4 carriers.  相似文献   
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165.
Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome, is a chronic and progressive X-linked lysosomal disease that mainly affects males. It occurs in 1 in every 65,000 to 1 in 132,000 births. There are two distinct forms of the disease based on age of onset and clinical course: mild and severe. MPS II affects many organ systems including the nervous, cardiovascular, gastrointestinal and respiratory systems. Complications can include vision problems, progressive hearing loss, thickened and elastic skin, mental impairment, and enlarged liver and spleen. We herein focus on the adaptive behavior of individuals with MPS II, and the impact of MPS II on the family system. Outcomes from the Vineland-II Adaptive Behavior Scales showed that the MPS II patient sample experienced significantly lower functioning in communication, daily living skills, socialization, and motor skills compared to normative data. Patients with severe MPS II were found to have significantly lower adaptive functioning in all domains, as compared to those with mild MPS II. Length of time on ERT had no significant relationship to adaptive functioning. Results from the Peds QL Family Impact Module indicated that families of patients with MPS II experienced a lower overall health-related quality of life and overall lower family functioning (including lower emotional and cognitive functioning) than those with chronic illnesses residing in an inpatient setting.  相似文献   
166.
Childhood cognitive and test-taking abilities have long-term implications for educational achievement and health, and may be influenced by household environmental exposures and neighborhood contexts. This study evaluates whether age 5 scores on the Wechsler Preschool and Primary Scale of Intelligence-Revised (WPPSI-R, administered in English) are associated with polycyclic aromatic hydrocarbon (PAH) exposure and neighborhood context variables including poverty, low educational attainment, low English language proficiency, and inadequate plumbing. The Columbia Center for Children’s Environmental Health enrolled African-American and Dominican-American New York City women during pregnancy, and conducted follow-up for subsequent childhood health outcomes including cognitive test scores. Individual outcomes were linked to data characterizing 1-km network buffers around prenatal addresses, home observations, interviews, and prenatal PAH exposure data from personal air monitors. Prenatal PAH exposure above the median predicted 3.5 point lower total WPPSI-R scores and 3.9 point lower verbal scores; the association was similar in magnitude across models with adjustments for neighborhood characteristics. Neighborhood-level low English proficiency was independently associated with 2.3 point lower mean total WPPSI-R score, 1.2 point lower verbal score, and 2.7 point lower performance score per standard deviation. Low neighborhood-level educational attainment was also associated with 2.0 point lower performance scores. In models examining effect modification, neighborhood associations were similar or diminished among the high PAH exposure group, as compared with the low PAH exposure group. Early life exposure to personal PAH exposure or selected neighborhood-level social contexts may predict lower cognitive test scores. However, these results may reflect limited geographic exposure variation and limited generalizability.  相似文献   
167.
Churches provide an innovative and underutilized setting for diabetes self-management programs for Latinos. This study sought to formulate a conceptual framework for designing church-based programs that are tailored to the needs of the Latino community and that utilize church strengths and resources. To inform this model, we conducted six focus groups with mostly Mexican-American Catholic adults with diabetes and their family members (N = 37) and found that participants were interested in church-based diabetes programs that emphasized information sharing, skills building, and social networking. Our model demonstrates that many of these requested components can be integrated into the current structure and function of the church. However, additional mechanisms to facilitate access to medical care may be necessary to support community members’ diabetes care.  相似文献   
168.
This article uses the Mobile Youth Survey (MYS) to quantitatively evaluate Elijah Anderson's seminal theory of African-American youth in Philadelphia, the Code of the Street. Using longitudinal data and Structural Equation Modeling, we identify characteristics that lead underclass youth to adopt or to reject a “street code” mentality. Like other studies of Anderson's Code of the Streets, we examine family and peer relationships, neighborhood control and stability, victimization and negative emotional reactions as predictors of adolescents' street code orientation. At the same time, we introduce for the first time, hopelessness, defined as a state of mind in which individuals have a negative perception of their future, into the intellectual and social equation. Results show that hopelessness plays an instrumental role in adopting street code beliefs. Specifically, adolescents reporting greater hopelessness in 2004 were more likely to identify with the street code in 2005; by extension, adolescents who identified with the street code in 2005 were also more involved in violence.  相似文献   
169.
This study presents an examination of characteristics of men who engage in bareback sex for purposes of bug chasing and bug giving. Drawing on personal ads posted on an Internet website geared for men seeking male sexual partners, the present analysis focuses on identifying characteristics of men seeking to become HIV infected (bug chasers) and men seeking to intentionally infect others with HIV (bug givers). Nearly one in ten ads posted during a one-year period are identified as from bug chasers or bug givers and serve as the sample for analysis. Results reveal a profile of bug chasers and bug givers, with demographic, appearance, sexual activity preferences, and degree of openness differences between the two groups.  相似文献   
170.
Two experiments investigated the possibility that external statements in the Rotter I-E scale are more depressing in tone than internal statements, and thus depressed subjects may respond to external items due to item mood level rather than locus of control content. Results of Experiment 1 revealed that the external alternative was rated as more depressing than its internal counterpart for the majority Of the 23 I-E items (18 for females and 15 for males), while a small number of I-E items (3 for females and 6 for males) contained internal and external statements rated as balanced for depressing Content. For two I-E items the internal alternative was rated as more depressing. Results of Experiment 2 revealed that endorsement of external items was significantly related to self-reported depression for both total I-E score and for the item subset where external statements(as revealed in Experiment 1) were the more depressing of the item pair. External endorsement was not significantly related to depression for the I-E item subset where options are balanced for mood level, while endorsement of internal statements was related to depression only for the item subset where the internal option was rated as more depressing. These results were interpreted as supporting prior research which demonstrated mood response set using altered Rotter I-E scale items, Implications for use of the Rotter I-E scale in the study of depression were discussed.  相似文献   
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