Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

Differentiating intolerance of uncertainty from three related but distinct constructs

Individual differences in uncertainty have been associated with heightened anxiety, stress and approach-oriented coping. Intolerance of uncertainty (IU) is a trait characteristic that arises from negative beliefs about uncertainty and its consequences. Researchers have established the central role of IU in the development of problematic worry and maladaptive coping, highlighting the importance of this construct to anxiety disorders. However, there is a need to improve our understanding of the phenomenology of IU. The goal of this paper was to present hypotheses regarding the similarities and differences between IU and three related constructs – intolerance of ambiguity, uncertainty orientation, and need for cognitive closure – and to call for future empirical studies to substantiate these hypotheses. To assist with achieving this goal, we conducted a systematic review of the literature, which also served to identify current gaps in knowledge. This paper differentiates these constructs by outlining each definition and general approaches to assessment, reviewing the existing empirical relations, and proposing theoretical similarities and distinctions. Findings may assist researchers in selecting the appropriate construct to address their research questions. Future research directions for the application of these constructs, particularly within the field of clinical and health psychology, are discussed.     

Bias? Who is Bias? Comments to Dellsén

Philosophia - (Dellsén, Philosophical Studies, 177(12), 3661–3678, 2020) argues that a positivistic defense of science’s objectivity is incoherent because bias in the...     

At the core of cyberaggression: A group-based explanation

In this study, prototypicality of the aggressor was tested as a group-level factor predicting social media users’ active participation in cyberaggression. Participants were exposed to a fictitious conversation, in which either a prototypical versus non-prototypical user posted an aggressive comment as a reply to a provocative comment. In line with self-categorization theory, we hypothesized that bystander participants would post an aggressive comment and rate the aggression as acceptable to a greater extent in the prototypical than in the non-prototypical condition. Furthermore, we predicted that perceived normativity of aggression would mediate the effect of prototypicality. Results supported these predictions and showed that prototypical members affect the extent to which collective aggressive behaviors in online interactions are approved and enacted. These findings highlight the importance of group-level factors in the study of cyberaggression and provide important information for understanding the psychological underpinnings of collective forms of online aggression.     

Review of: Svetlana Klimova: Russian Intelligentsia in Search of an Identity (Between Dostoevsky’s Oppositions and Tolstoy’s Holism), Leiden,Brill, 2020, Hardcover,ISBN 978-90-04-44060-9, $ 82,80

Studies in East European Thought -     

Longitudinal Associations Between the Five-Factor Model of Personality and The Bi-Factor Model of Psychopathology: Continuity,Pathoplasty and Complication Effects in Adolescents

The study of the bifactor structure of psychopathology, which includes a general factor of psychopathology (or p factor) in addition to the internalizing and externalizing factors, has gained attention. However, its associations with the Five-Factor Model (FFM) of personality has been addressed in few studies, and none has examined different plausible etiological models (i.e., continuity, pathoplasty, complication) to explain its relationship, which is the aim of the present research. Additionally, the longitudinal association of the General Factor of Personality (GFP) and the p factor will be also explored. Personality and psychopathological symptoms of high school students were assessed at three time points (once a year) (n?=?655; M?=?13.79, SD?=?1.24; 49.8% girls). Confirmatory Factor Analysis (and measurement invariance across waves) were tested for the traits, the GFP and the bifactor model of psychopathology. While the bifactor model and the one-factor solution for each personality trait displayed good fit to the data and remained invariant over time, the structure of the GFP was adequate and invariant in two of the three waves. The resulting factors were included in cross-lagged panel models and showed that the FFM traits and the psychopathology factors influenced each other reciprocally. Most associations fell in line with the continuity model, but minor pathoplastic and complication effects were also reported. Similar associations were found between the GFP and the p factor. These results suggest that interventions in riskier personality profiles might prevent the development of general and more specific psychopathology spectra.

     

Adversariality in Argumentation: Shortcomings of Minimal Adversariality and A Possible Reconstruction

Argumentation - Minimal adversariality consists in the opposition of contradictory conclusions in argumentation, and its usual metaphorical expression as a game between combating arguers has seen...     

Context specificity of latent inhibition in the snail Cornu aspersum

Animal Cognition - The present study was conducted to assess the context specificity of latent inhibition (LI) in the snail Cornu aspersum, using the appetitive Pavlovian Conditioning procedure of...     

Color Selectivity of the Spatial Congruency Effect: Evidence from the Focused Attention Paradigm

The multisensory response enhancement (MRE), occurring when the response to a visual target integrated with a spatially congruent sound is stronger than the response to the visual target alone, is believed to be mediated by the superior colliculus (SC) (Stein & Meredith, 1993). Here, we used a focused attention paradigm to show that the spatial congruency effect occurs with red (SC-effective) but not blue (SC-ineffective) visual stimuli, when presented with spatially congruent sounds. To isolate the chromatic component of SC-ineffective targets and to demonstrate the selectivity of the spatial congruency effect we used the random luminance modulation technique (Experiment 1) and the tritanopic technique (Experiment 2). Our results indicate that the spatial congruency effect does not require the distribution of attention over different sensory modalities and provide correlational evidence that the SC mediates the effect.