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Tatjana A. Nazir Lianna Hrycyk Quentin Moreau Victor Frak Anne Cheylus Laurent Ott Oliver Lindemann Martin H. Fischer Yves Paulignan Yvonne Delevoye-Turrell 《Behavior research methods》2017,49(1):61-73
Research in cognitive neuroscience has shown that brain structures serving perceptual, emotional, and motor processes are also recruited during the understanding of language when it refers to emotion, perception, and action. However, the exact linguistic and extralinguistic conditions under which such language-induced activity in modality-specific cortex is triggered are not yet well understood. The purpose of this study is to introduce a simple experimental technique that allows for the online measure of language-induced activity in motor structures of the brain. This technique consists in the use of a grip force sensor that captures subtle grip force variations while participants listen to words and sentences. Since grip force reflects activity in motor brain structures, the continuous monitoring of force fluctuations provides a fine-grained estimation of motor activity across time. In other terms, this method allows for both localization of the source of language-induced activity to motor brain structures and high temporal resolution of the recorded data. To facilitate comparison of the data to be collected with this tool, we present two experiments that describe in detail the technical setup, the nature of the recorded data, and the analyses (including justification about the data filtering and artifact rejection) that we applied. We also discuss how the tool could be used in other domains of behavioral research. 相似文献
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Psychometrika - Multinomial processing trees (MPTs) are a popular class of cognitive models for categorical data. Typically, researchers compare several MPTs, each equipped with many parameters,... 相似文献
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Lateral differences in habituation of ipsilateral head-turning to repeated tactile perioral stimulation following midline head restriction was studied in 44 full-term neonates. Left-sided stimulation had a significantly greater and faster decremental effect than right-sided stimulation. Even in the absence of tactile stimulation (Control Group), head-turning to the left decreased systematically whereas head-turning to the right did not. The transient efficacy of prior midline head restriction for the elimination of lateral differences in both spontaneous head movements and responsiveness to tactile input suggests that behavioral asymmetry is already well-established in the newborn. 相似文献
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Céline De Looze Noémie Moreau Laurent Renié Finnian Kelly Alain Ghio Audrey Rico Bertrand Audoin François Viallet Jean Pelletier Caterina Petrone 《Journal of Neuropsychology》2019,13(1):22-45
Cognitive impairment (CI) affects 40–65% of patients with multiple sclerosis (MS). CI can have a negative impact on a patient's everyday activities, such as engaging in conversations. Speech production planning ability is crucial for successful verbal interactions and thus for preserving social and occupational skills. This study investigates the effect of cognitive-linguistic demand and CI on speech production planning in MS, as reflected in speech prosody. A secondary aim is to explore the clinical potential of prosodic features for the prediction of an individual's cognitive status in MS. A total of 45 subjects, that is 22 healthy controls (HC) and 23 patients in early stages of relapsing-remitting MS, underwent neuropsychological tests probing specific cognitive processes involved in speech production planning. All subjects also performed a read speech task, in which they had to read isolated sentences manipulated as for phonological length. Results show that the speech of MS patients with CI is mainly affected at the temporal level (articulation and speech rate, pause duration). Regression analyses further indicate that rate measures are correlated with working memory scores. In addition, linear discriminant analysis shows the ROC AUC of identifying MS patients with CI is 0.70 (95% confidence interval: 0.68–0.73). Our findings indicate that prosodic planning is deficient in patients with MS-CI and that the scope of planning depends on patients’ cognitive abilities. We discuss how speech-based approaches could be used as an ecological method for the assessment and monitoring of CI in MS. 相似文献
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Monocular deprivation in adult mice alters visual acuity and single-unit activity 总被引:1,自引:0,他引:1
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Fischer QS Graves A Evans S Lickey ME Pham TA 《Learning & memory (Cold Spring Harbor, N.Y.)》2007,14(4):277-286
It has been discovered recently that monocular deprivation in young adult mice induces ocular dominance plasticity (ODP). This contradicts the traditional belief that ODP is restricted to a juvenile critical period. However, questions remain. ODP of young adults has been observed only using methods that are indirectly related to vision, and the plasticity of young adults appears diminished in comparison with juveniles. Therefore, we asked whether the newly discovered adult ODP broadly reflects plasticity of visual cortical function and whether it persists into full maturity. Single-unit activity is the standard physiological marker of visual cortical function. Using a more optimized protocol for recording single-units, we find evidence of adult ODP of single-units and show that it is most pronounced in deep cortical layers. Furthermore, using visual evoked potentials (VEP), we find that ODP is equally robust in young adults and mature adults and is observable after just one day of monocular deprivation. Finally, we find that monocular deprivation in adults changes spatial frequency thresholds of the VEP, decreasing the acuity of the deprived pathway and improving the acuity of the non-deprived pathway. Thus, in mice, the primary visual cortex is capable of remarkable adaptation throughout life. 相似文献
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Gérard Moreau 《Journal of International Migration and Integration》2000,1(1):101-120
In this article the author compares integration policies in some European countries and Canada. Despite the varying political or ideological wordings and histories all countries reviewed face similar social problems in the integration of migrants. Because public authorities act with pragmatism and without any strict theoretical model, policies are more comparable that one might suppose, although sometimes differences are marked. The article first points out the similarities in the policies of each country. Cultures and languages of origin, migrants’ associations, and unemployment are discussed briefly, as well as trianing of public servants, and struggle against racism, and urban segregation. A second section shows clear distinctions between the countries’ policies in two respects: politicization and relationships between searchers and policy-makers. The author then discusses several initiatives to improve integration using pre-existing programmes in other countries as examples. These include: welcome programmes for new immigrants, preschool programmes, dropout prevention programmes, globally conceived urban projects, as well decentralization of local authority, active local participation, and strong links with research work. The article concludes by supporting the thesis that no efficient integration policy can succeed if it does not strengthen the overall social link. 相似文献