自我损耗、情绪动机对冲动决策的影响

以大学生为被试,探讨自我损耗、情绪动机对冲动决策的影响。采用2×2×2的混合实验设计,组内变量为自我损耗,组间变量为情绪动机方向和强度,使用双任务范式操作自我损耗,使用情绪动机图片启动被试的情绪动机,使用延迟折扣任务的指标k值测量冲动决策。结果发现,高趋近动机的k值大于低趋近动机,高回避动机的k值大于低回避动机。结果表明,自我损耗、情绪动机对冲动决策有明显影响。     

内隐多效性选择的ERP证据

采用事件相关电位技术,考察内隐多效性选择及其神经机制。被试的任务是认真观看配对的纯色图片刺激,并进行分类按键反应。实验结果发现,在P2上,积极启动刺激比对照刺激激发了更大的P2波幅; 对比对照刺激,积极启动刺激在左脑、大脑中部和后脑诱发了更大的P2波幅,其中右脑的效应最大。在N2上,积极启动刺激比对照刺激激发了更小的N2波幅; 对比对照刺激,积极启动刺激在左脑、大脑中部和后脑诱发了更小的N2波幅,其中右脑的效应最大。在P3上,积极启动刺激比对照刺激激发了更大的P3波幅; 对比对照刺激,积极启动刺激在左脑、大脑中部和后脑诱发了更大的P3波幅,其中右脑的效应最大。研究结果表明当外显目标与内隐目标同时被呈现时,被试趋向于做多效性选择,这可能表明无意识信息加工具有相当大的权重。且右后部脑区可能是加工多效性刺激的核心和关键区域,P3成分可能反应了内隐多效性选择的精细加工过程,能够作为内隐多效性选择的有效的ERPs指标。     

Impact of a Patient-Facing Enhanced Genomic Results Report to Improve Understanding,Engagement, and Communication

“The objective of this study was to” test the effectiveness of an enhanced genomic report on patient-centered outcome domains including communication, engagement and satisfaction. “Study design utilized” a prospective, randomized, mixed-methods desctiptive study of a whole genome sequencing results report, GenomeCOMPASS?, that was accessed by providers through the electronic health record and by patients through the associated patient portal. “The study was set in” an integrated healthcare delivery system in central Pennsylvania. “Eighty-four” parents of 46 children with undiagnosed Intellectual Disability, Autism Spectrum Disorder and/or multiple congenital anomalies who had participated in a previous study offering whole genome sequencing for their affected child were invited to enroll. Fifty-two parents enrolled. Following a traditional genetics results informing visit, the study coordinator stratified families by diagnostic result and uninformative result and then randomized families within each group to an intervention arm to receive the GenomeCOMPASS? report or to the usual care arm to receive a summary letter from the medical geneticist. A letter inviting enrollment included a baseline survey, which once returned, constituted enrollment. Surveys were administered at 3 months post-genetics visit. At 6 months, the usual care arm crossed over to receive the intervention and were administered an additional survey at 3 months. Qualitative interviews were conducted following survey completion to augment the survey data regarding the patient centered outcomes of interest. Patient reported outcomes including communication, engagement, empowerment and satisfaction. In the intervention arm, GenomeCOMPASS? reports were released to 14 families (N?=?28 parents) and of those 21 (75%) returned 3 month surveys. In the usual care arm, 12 families (N?=?24 parents) received usual care summary letters and of those 20 (83%) returned 3 month surveys. At crossover, GenomeCOMPASS? reports were released to 20 individuals and 15 (75%) returned 3 month surveys. Qualitative interviews were conducted with 5 individuals. Use of the GenomeCOMPASS? report was reported by this small group of parents to improve communication with providers and non-health professionals such as educators and therapists and led to increased engagement and high satisfaction. Providers and others involved in the children’s care also endorsed the report’s effectiveness. Reports that addressed negative findings, i.e. uninformative results, were not found to be useful. Although the number of users was small, this study supports that customizable template reports may provide a useful and durable source of information that can support and enhance the information provided by genetics professionals in traditional face-to-face encounters. Trial registration: Clinicaltrials.gov (Record 2013–0594).     

不同加工与记忆编码关系的ERP研究

通过事件相关电位(ERPs)记录,探讨了深、浅2种加工与记忆编码的相互关系。研究结果表明,（1）在深、浅两种加工条件下,首次使用汉字材料,获得了ERP相继记忆效应（Dm),随后再认正确的ERPs比随后再认不正确的ERPs有更大的晚正成分。（2）深加工的Dm效应始于N2波的前支（230－280ms)和N2波之后（395－800ms);而浅加工的Dm效应发生在345－490ms之间。深、浅加工的Dm效 涉及不同的脑区,这一结果支持深、浅两种加工的Dm效应可能是分离的结论。     

1993~2013年常驻高海拔地区军人心理健康状态的横断历史研究

研究为探索常驻高海拔地区军人心理健康水平如何随社会年代变迁而改变,运用了横断历史元分析的方法,对1993年至2013年38篇采用90项症状自评量表(SCL-90)的文献调查数据进行分析,考察了11454名常驻高海拔地区军人在该量表上9个因子得分随年代变化的趋势.结果发现:(1)SCL-90的7个因子均值与年代负相关,且不受期刊类型等的影响.20年来,7个因子下降了5%~15%不等.其中,强迫变化最大,抑郁、焦虑、人际敏感、偏执和精神病性均变化明显.这说明,常驻高海拔地区军人心理健康虽有所波动但整体水平逐步提升,变化幅度大致属于中等程度.(2)当年军费占GDP比值、居民消费水平指数与SCL-90部分因子均值负相关显著;5年前的居民消费水平指数与7个因子显著负相关.这说明,国防建设的经济投入和居民消费水平可能是影响常驻高海拔地区军人心理健康水平的重要因素.     

青少年大五人格对网络成瘾的影响:家庭功能的中介作用

目的:探究家庭功能在人格特征与网络成瘾之间的中介作用。方法:973名中学生被试完成基本人口学问卷、网络成瘾量表、人格五因素问卷、家庭功能评定量表。结果:(1)人格特征可以显著预测网络成瘾。其中,情绪性人格可以显著正向预测网络成瘾,责任心、宜人性显著负向预测网络成瘾。(2)家庭功能在情绪性、责任心对网络成瘾的影响具有部分中介作用、在宜人性对网络成瘾的影响具有完全中介作用。结论:在治疗中,可针对网络成瘾者的家庭功能进行积极干预,从而减轻其成瘾症状。     

Four-phonon model of soft-matter quasicrystals for studying thermodynamics

Four-phonon model of soft-matter quasicrystals is proposed, in which there are three solid phonons and one fluid phonon. With this model, the vibration spectrum of soft-matter quasicrystals can be obtained. The generalized Debye frequency, generalized Debye temperature and the thermodynamic functions of soft-matter quasicrystals are observed. The results on the specific heat of soft-matter quasicrystals demonstrate the contributions of both solid phonons and fluid phonon, respectively.     

化疗在局部晚期鼻咽癌中的适度应用

鼻咽癌是我国高发恶性肿瘤之一,发病率为头颈部恶性肿瘤之首。鼻咽癌对放疗、化疗均敏感。单纯的放射治疗虽然能够使早期患者获得很好的局部控制率,但是对于局部晚期患者而言,其5年生存率难以令人满意,治疗失败主要是因为区域复发和远处转移。化学治疗对放疗起到了补充作用,临床应用目前主要有同期化疗、辅助化疗、诱导化疗三种。本文对过去20年间化疗在局部晚期鼻咽癌治疗中的应用归纳总结。     

元认知在线监控和离线监控与一般元认知能力的关系

该研究探索元认知在线监控和离线监控与一般元认知能力之间的关系,采用跟踪击键任务、学习判断任务和大学生元认知能力量表,对40名大学生进行研究。结果表明:(1)元认知离线监控对一般元认知能力各个子成分的预测作用受元认知在线监控的影响;(2)元认知在线、离线监控对一般元认知能力的预测作用是彼此独立的。